Motif ID: Meis2

Z-value: 1.314


Transcription factors associated with Meis2:

Gene SymbolEntrez IDGene Name
Meis2 ENSMUSG00000027210.14 Meis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis2mm10_v2_chr2_-_116064512_1160645980.824.8e-09Click!


Activity profile for motif Meis2.

activity profile for motif Meis2


Sorted Z-values histogram for motif Meis2

Sorted Z-values for motif Meis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_194619815 8.630 ENSMUST00000027952.5
 Plxna2
plexin A2
chr7_+_44850393 5.592 ENSMUST00000136232.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr4_+_128058962 5.068 ENSMUST00000184063.1
 Csmd2
CUB and Sushi multiple domains 2
chr11_+_78324200 5.001 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr19_+_42247544 4.799 ENSMUST00000122375.1
 Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr5_-_100159261 4.561 ENSMUST00000139520.1
 Tmem150c
transmembrane protein 150C
chr9_-_121495678 4.492 ENSMUST00000035120.4
 Cck
cholecystokinin
chr5_-_109558957 4.475 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2
chr3_-_82074639 4.422 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr12_-_24493656 4.197 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr6_+_49822710 4.114 ENSMUST00000031843.6
 Npy
neuropeptide Y
chr1_-_52727457 3.954 ENSMUST00000156876.1
ENSMUST00000087701.3
 Mfsd6

major facilitator superfamily domain containing 6

chr17_+_8924109 3.929 ENSMUST00000149440.1
 Pde10a
phosphodiesterase 10A
chr18_+_36939178 3.921 ENSMUST00000115662.2
 Pcdha2
protocadherin alpha 2
chr15_-_100599864 3.908 ENSMUST00000177247.2
ENSMUST00000177505.2
 Pou6f1

POU domain, class 6, transcription factor 1

chr8_+_120114144 3.765 ENSMUST00000108948.1
ENSMUST00000034281.6
ENSMUST00000108951.1
 6430548M08Rik


RIKEN cDNA 6430548M08 gene


chr3_-_107518001 3.743 ENSMUST00000169449.1
ENSMUST00000029499.8
 Slc6a17

solute carrier family 6 (neurotransmitter transporter), member 17

chr9_-_86880414 3.723 ENSMUST00000074501.5
ENSMUST00000098495.3
ENSMUST00000074468.6
ENSMUST00000036347.6
 Snap91



synaptosomal-associated protein 91



chr7_+_48959089 3.699 ENSMUST00000183659.1
 Nav2
neuron navigator 2
chr3_-_84270782 3.522 ENSMUST00000054990.4
 Trim2
tripartite motif-containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 8.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.2 7.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 6.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
1.0 5.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 5.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.5 5.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 4.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.7 4.5 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.4 4.5 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
1.0 4.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.8 4.1 GO:0019732 antifungal humoral response(GO:0019732)
0.5 4.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 4.0 GO:0036503 ERAD pathway(GO:0036503)
0.5 3.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 3.9 GO:0046069 cGMP catabolic process(GO:0046069)
1.2 3.7 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.9 3.7 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.7 3.7 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 3.6 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.3 3.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 8.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 6.7 GO:0042641 actomyosin(GO:0042641)
0.7 6.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 5.9 GO:0043195 terminal bouton(GO:0043195)
0.5 5.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 5.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 5.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 4.8 GO:0097060 synaptic membrane(GO:0097060)
0.9 4.7 GO:0044316 cone cell pedicle(GO:0044316)
0.3 4.5 GO:0043203 axon hillock(GO:0043203)
0.1 4.5 GO:0043198 dendritic shaft(GO:0043198)
0.2 3.9 GO:0001891 phagocytic cup(GO:0001891)
0.7 3.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 3.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 3.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 3.5 GO:0061700 GATOR2 complex(GO:0061700)
0.2 3.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 3.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 3.1 GO:0016363 nuclear matrix(GO:0016363)
0.4 2.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 8.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 7.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.7 6.4 GO:0004383 guanylate cyclase activity(GO:0004383)
1.5 5.9 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 5.2 GO:0005125 cytokine activity(GO:0005125)
0.8 5.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 4.3 GO:0003779 actin binding(GO:0003779)
0.2 4.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 4.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 4.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 3.9 GO:0030553 cGMP binding(GO:0030553)
0.1 3.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.7 3.7 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 3.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 3.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 3.5 GO:0017022 myosin binding(GO:0017022)
0.1 3.2 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 3.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 3.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.9 GO:0030552 cAMP binding(GO:0030552)