Motif ID: Meox2

Z-value: 0.666


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_371085460.309.4e-02Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

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Top targets:


Showing 1 to 20 of 149 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_25980039 3.238 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr14_+_26119811 3.124 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26259109 2.509 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr8_-_46294592 1.971 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr16_+_42907563 1.951 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr5_-_62766153 1.487 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_10320229 1.382 ENSMUST00000053066.6
 Qk
quaking
chr14_+_25979401 1.377 ENSMUST00000173580.1
 Duxbl1
double homeobox B-like 1
chr11_-_110095937 1.363 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr14_+_33923582 1.154 ENSMUST00000168727.1
 Gdf10
growth differentiation factor 10
chr3_-_152982240 1.142 ENSMUST00000044278.5
 St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr14_+_26119173 1.054 ENSMUST00000174564.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 1.054 ENSMUST00000172517.1
 Duxbl3
double homeobox B-like 3
chr3_+_53845086 0.976 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr11_-_110095974 0.965 ENSMUST00000100287.2
 Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr10_-_88683021 0.961 ENSMUST00000004473.8
 Spic
Spi-C transcription factor (Spi-1/PU.1 related)
chr3_+_107291215 0.946 ENSMUST00000029502.7
 Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr19_-_9559204 0.937 ENSMUST00000090527.3
 Stxbp3b
syntaxin-binding protein 3B
chr3_+_127553462 0.930 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr7_-_5413145 0.907 ENSMUST00000108569.2
 Vmn1r58
vomeronasal 1 receptor 58

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 2.0 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.1 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.5 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 1.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 1.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 0.9 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.9 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 0.7 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 0.7 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.2 0.7 GO:0007128 meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.2 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.6 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.5 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.5 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.0 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 1.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.4 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)