Motif ID: Mga

Z-value: 0.575


Transcription factors associated with Mga:

Gene SymbolEntrez IDGene Name
Mga ENSMUSG00000033943.9 Mga

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_1198973050.125.2e-01Click!


Activity profile for motif Mga.

activity profile for motif Mga


Sorted Z-values histogram for motif Mga

Sorted Z-values for motif Mga



Network of associatons between targets according to the STRING database.



First level regulatory network of Mga

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 2.853 ENSMUST00000168589.1
 Sla
src-like adaptor
chr4_+_43381979 1.910 ENSMUST00000035645.5
ENSMUST00000144911.1
 Rusc2

RUN and SH3 domain containing 2

chr11_+_49203465 1.457 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
 Zfp62


zinc finger protein 62


chr11_+_49203285 1.449 ENSMUST00000109198.1
ENSMUST00000137061.2
 Zfp62

zinc finger protein 62

chr6_-_41636389 1.358 ENSMUST00000031902.5
 Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr15_-_43869993 1.319 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr10_+_81575257 1.308 ENSMUST00000135211.1
 Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr8_+_12984246 1.268 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
 Mcf2l


mcf.2 transforming sequence-like


chr9_+_57940104 1.129 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr10_+_81575306 1.106 ENSMUST00000146916.1
 Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr14_-_55900188 1.099 ENSMUST00000111325.3
 Sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr11_+_113657375 1.017 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
 Cog1


component of oligomeric golgi complex 1


chrY_-_6681243 0.975 ENSMUST00000115940.1
 Gm21719
predicted gene, 21719
chr8_+_83165348 0.960 ENSMUST00000034145.4
 Tbc1d9
TBC1 domain family, member 9
chr1_+_171419027 0.956 ENSMUST00000171362.1
 Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr5_-_138619751 0.906 ENSMUST00000085852.4
ENSMUST00000110905.2
 Zfp68

zinc finger protein 68

chr5_+_149265035 0.874 ENSMUST00000130144.1
ENSMUST00000071130.3
 Alox5ap

arachidonate 5-lipoxygenase activating protein

chr3_+_13946368 0.783 ENSMUST00000171075.1
ENSMUST00000108372.2
 Ralyl

RALY RNA binding protein-like

chr1_+_52008210 0.768 ENSMUST00000027277.5
 Stat4
signal transducer and activator of transcription 4
chr6_-_149188648 0.737 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
 Amn1


antagonist of mitotic exit network 1


chr5_-_138619702 0.701 ENSMUST00000063262.4
 Zfp68
zinc finger protein 68
chr4_-_117125618 0.701 ENSMUST00000183310.1
 Btbd19
BTB (POZ) domain containing 19
chrX_+_35888808 0.700 ENSMUST00000033419.6
 Dock11
dedicator of cytokinesis 11
chr8_+_3353415 0.686 ENSMUST00000098966.3
 A430078G23Rik
RIKEN cDNA A430078G23 gene
chr16_-_9994921 0.653 ENSMUST00000115835.1
 Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr17_-_32350569 0.645 ENSMUST00000050214.7
 Akap8l
A kinase (PRKA) anchor protein 8-like
chr8_+_3393018 0.608 ENSMUST00000004684.6
ENSMUST00000145394.1
 Arhgef18

rho/rac guanine nucleotide exchange factor (GEF) 18

chr3_+_89773562 0.590 ENSMUST00000038356.8
 Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr5_-_86676346 0.588 ENSMUST00000038448.6
 Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr4_+_95967322 0.564 ENSMUST00000107083.1
 Hook1
hook homolog 1 (Drosophila)
chr10_+_18055711 0.558 ENSMUST00000154718.1
ENSMUST00000126390.1
ENSMUST00000164556.1
ENSMUST00000150029.1
 Reps1



RalBP1 associated Eps domain containing protein



chr2_+_83644435 0.532 ENSMUST00000081591.6
 Zc3h15
zinc finger CCCH-type containing 15
chr13_+_29016267 0.531 ENSMUST00000140415.1
 A330102I10Rik
RIKEN cDNA A330102I10 gene
chr1_+_75435930 0.522 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
 Gmppa






GDP-mannose pyrophosphorylase A






chr7_-_24316590 0.482 ENSMUST00000108436.1
ENSMUST00000032673.8
 Zfp94

zinc finger protein 94

chr5_-_138619653 0.478 ENSMUST00000129832.1
 Zfp68
zinc finger protein 68
chr5_-_120777628 0.412 ENSMUST00000044833.8
 Oas3
2'-5' oligoadenylate synthetase 3
chr2_+_55411790 0.390 ENSMUST00000155997.1
ENSMUST00000128307.1
 Gm14033

predicted gene 14033

chr1_+_75436002 0.376 ENSMUST00000131545.1
ENSMUST00000141124.1
 Gmppa

GDP-mannose pyrophosphorylase A

chr16_-_45844303 0.356 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr7_-_30880263 0.339 ENSMUST00000108125.2
 Cd22
CD22 antigen
chr2_-_129371131 0.338 ENSMUST00000028881.7
 Il1b
interleukin 1 beta
chr3_+_124321031 0.337 ENSMUST00000058994.4
 Tram1l1
translocation associated membrane protein 1-like 1
chr2_+_144527718 0.321 ENSMUST00000028914.2
ENSMUST00000110017.2
 Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr12_-_54695885 0.317 ENSMUST00000067272.8
 Eapp
E2F-associated phosphoprotein
chr10_-_86011833 0.312 ENSMUST00000105304.1
ENSMUST00000061699.5
 Bpifc

BPI fold containing family C

chr8_-_84104773 0.299 ENSMUST00000041367.7
 Dcaf15
DDB1 and CUL4 associated factor 15
chr9_-_85749308 0.293 ENSMUST00000039213.8
 Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr6_-_56923927 0.293 ENSMUST00000031793.5
 Nt5c3
5'-nucleotidase, cytosolic III
chr12_-_54695813 0.258 ENSMUST00000110713.3
 Eapp
E2F-associated phosphoprotein
chr15_+_51877429 0.241 ENSMUST00000137116.2
ENSMUST00000161651.1
ENSMUST00000059599.9
 Utp23


UTP23, small subunit (SSU) processome component, homolog (yeast)


chr12_+_84316830 0.234 ENSMUST00000045931.10
 Zfp410
zinc finger protein 410
chr11_-_21572193 0.222 ENSMUST00000102874.4
 Mdh1
malate dehydrogenase 1, NAD (soluble)
chr12_-_54695829 0.203 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
 Eapp



E2F-associated phosphoprotein



chr7_-_3720382 0.202 ENSMUST00000078451.6
 Pirb
paired Ig-like receptor B
chr7_+_24081888 0.173 ENSMUST00000068975.3
 Zfp180
zinc finger protein 180
chr13_-_8870999 0.150 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
 Wdr37


WD repeat domain 37


chr7_+_5080214 0.148 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
 Epn1



epsin 1



chr17_+_7945653 0.135 ENSMUST00000097423.2
 Rsph3a
radial spoke 3A homolog (Chlamydomonas)
chr19_-_40588374 0.132 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
 Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chr5_-_31108218 0.130 ENSMUST00000182776.1
ENSMUST00000182444.1
 Slc30a3

solute carrier family 30 (zinc transporter), member 3

chr10_+_115384951 0.110 ENSMUST00000036044.8
 Zfc3h1
zinc finger, C3H1-type containing
chrX_+_163909132 0.103 ENSMUST00000033734.7
ENSMUST00000112294.2
 Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr4_-_62525036 0.100 ENSMUST00000030091.3
 Pole3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr14_+_64652524 0.076 ENSMUST00000100473.4
 Kif13b
kinesin family member 13B
chr14_+_79397772 0.043 ENSMUST00000022600.2
 Mtrf1
mitochondrial translational release factor 1
chr5_+_100196611 0.042 ENSMUST00000066813.1
 Gm9932
predicted gene 9932
chr4_+_62525369 0.038 ENSMUST00000062145.1
 4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr19_+_47228804 0.036 ENSMUST00000111807.3
 Neurl1a
neuralized homolog 1A (Drosophila)
chr17_-_6948283 0.032 ENSMUST00000024572.9
 Rsph3b
radial spoke 3B homolog (Chlamydomonas)
chr15_+_51877742 0.028 ENSMUST00000136129.1
 Utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr10_+_75212065 0.014 ENSMUST00000105421.2
 Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chr14_-_18893376 0.009 ENSMUST00000151926.1
 Ube2e2
ubiquitin-conjugating enzyme E2E 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.1 1.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.6 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.4 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.1 0.3 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.6 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 2.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) stress response to metal ion(GO:0097501)
0.0 0.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.9 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.1 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.0 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)