Motif ID: Msx1_Lhx9_Barx1_Rax_Dlx6

Z-value: 0.540


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Raxmm10_v2_chr18_-_65939048_65939089-0.512.4e-03Click!
Msx1mm10_v2_chr5_-_37824580_37824584-0.336.3e-02Click!
Lhx9mm10_v2_chr1_-_138848576_138848603-0.291.1e-01Click!
Dlx6mm10_v2_chr6_+_6863769_6863797-0.096.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Msx1_Lhx9_Barx1_Rax_Dlx6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_134747241 3.521 ENSMUST00000015138.9
Eln
elastin
chr5_-_62766153 3.493 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_136171722 3.101 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr9_+_118478344 3.000 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478182 2.952 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr1_-_155417394 2.870 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr8_+_54954728 2.808 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr2_+_116067213 2.740 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr1_-_155417283 2.514 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr7_+_126950518 2.192 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr9_-_40346290 2.095 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr16_+_45093611 1.967 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr7_+_126950687 1.933 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr2_-_116067391 1.894 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr4_-_14621805 1.853 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr16_+_42907563 1.621 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr17_-_90088343 1.492 ENSMUST00000173917.1
Nrxn1
neurexin I
chr7_+_126950837 1.488 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr11_-_87359011 1.466 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr19_+_26749726 1.458 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_-_83487708 1.294 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr17_-_49564262 1.259 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr6_-_126645784 1.247 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr16_-_74411292 1.234 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr10_+_39612934 1.226 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr2_-_45117349 1.132 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr10_+_73821857 1.121 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr1_+_104768510 1.115 ENSMUST00000062528.8
Cdh20
cadherin 20
chr17_+_3397189 1.090 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr1_-_158356258 1.084 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr1_-_79440039 1.081 ENSMUST00000049972.4
Scg2
secretogranin II
chr5_-_77115145 1.045 ENSMUST00000081964.5
Hopx
HOP homeobox
chr18_+_23415400 1.039 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr11_-_26210553 0.998 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr5_-_123141067 0.985 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr16_-_42340595 0.967 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr4_-_14621494 0.931 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr18_+_57468478 0.923 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr12_+_49382791 0.877 ENSMUST00000179669.1
Foxg1
forkhead box G1
chr18_-_37969742 0.865 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr16_-_97170707 0.847 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr13_+_23574381 0.845 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr11_-_98053415 0.835 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr15_-_66812593 0.820 ENSMUST00000100572.3
Sla
src-like adaptor
chr6_+_63255971 0.805 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr10_-_25200110 0.799 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr16_-_45724600 0.748 ENSMUST00000096057.4
Tagln3
transgelin 3
chr3_+_55461758 0.684 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr8_-_109251698 0.677 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr9_+_32116040 0.669 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr7_-_73541738 0.648 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr15_-_8710734 0.648 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_79771305 0.639 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr13_+_83732438 0.626 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr4_+_97777780 0.612 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr15_-_8710409 0.606 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_-_81493725 0.585 ENSMUST00000119121.1
Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr12_-_91849081 0.580 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr3_+_68572245 0.564 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr2_+_20737306 0.559 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr6_+_8948608 0.542 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr2_-_77703252 0.533 ENSMUST00000171063.1
Zfp385b
zinc finger protein 385B
chr4_+_108719649 0.521 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr2_-_79456750 0.516 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr5_-_62765618 0.513 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_29888570 0.508 ENSMUST00000171691.1
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr3_+_62419668 0.506 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chrX_+_166344692 0.504 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr12_+_38780817 0.489 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr6_+_145934113 0.486 ENSMUST00000032383.7
Sspn
sarcospan
chrX_-_143933204 0.473 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr12_+_38780284 0.466 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr15_+_21111452 0.463 ENSMUST00000075132.6
Cdh12
cadherin 12
chr9_+_45370185 0.459 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr19_+_26750939 0.435 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_29071597 0.434 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr12_+_52699297 0.423 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr11_+_102285161 0.391 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr4_-_14621669 0.375 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr18_+_37819543 0.368 ENSMUST00000055935.5
Pcdhga9
protocadherin gamma subfamily A, 9
chr3_+_96268654 0.363 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chr12_+_74297474 0.360 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr2_-_6721606 0.329 ENSMUST00000150624.2
ENSMUST00000142941.1
ENSMUST00000100429.4
ENSMUST00000182879.1
Celf2



CUGBP, Elav-like family member 2



chr6_-_57535422 0.329 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr4_+_21848039 0.326 ENSMUST00000098238.2
ENSMUST00000108229.1
Sfrs18

serine/arginine-rich splicing factor 18

chr1_+_132298606 0.322 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr3_+_86070915 0.318 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chrX_-_143933089 0.314 ENSMUST00000087313.3
Dcx
doublecortin
chr8_+_83666827 0.302 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr11_-_119547744 0.283 ENSMUST00000026670.4
Nptx1
neuronal pentraxin 1
chr13_+_42680565 0.281 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr16_-_4880284 0.276 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr2_+_71528657 0.275 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr17_+_75005523 0.275 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr13_-_113663670 0.269 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr5_-_23616528 0.268 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr5_+_13398688 0.262 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_-_155056784 0.259 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr3_+_151437887 0.255 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr12_+_38783503 0.250 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr9_-_103222063 0.247 ENSMUST00000170904.1
Trf
transferrin
chr14_-_108914237 0.247 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chrX_-_75416533 0.244 ENSMUST00000033542.4
Mtcp1
mature T cell proliferation 1
chr2_+_73271925 0.243 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr3_-_94412883 0.222 ENSMUST00000181305.1
1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr2_-_64975762 0.220 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr13_+_80883403 0.219 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3
chr16_-_63864114 0.219 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr13_-_23574196 0.209 ENSMUST00000105106.1
Hist1h2bf
histone cluster 1, H2bf
chr2_+_106693185 0.207 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr5_+_14025305 0.193 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_-_6721890 0.193 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr8_+_45658666 0.190 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr5_+_64812336 0.185 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr10_+_127421124 0.185 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr15_-_79285502 0.182 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr17_-_29007925 0.178 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr3_+_66219909 0.176 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr11_+_116843278 0.174 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr8_+_56551090 0.173 ENSMUST00000040218.5
ENSMUST00000110322.3
Fbxo8

F-box protein 8

chr3_-_116253467 0.165 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr1_-_172027251 0.162 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr3_+_32436151 0.152 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr7_-_73537621 0.150 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr12_-_48559971 0.144 ENSMUST00000169406.1
Gm1818
predicted gene 1818
chr1_-_152625212 0.143 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr12_+_111814170 0.143 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr17_+_46161021 0.142 ENSMUST00000024748.7
ENSMUST00000172170.1
Gtpbp2

GTP binding protein 2

chr8_+_45658731 0.141 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr12_+_38783455 0.139 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr5_-_137684665 0.132 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr15_+_92597104 0.129 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr8_+_107031218 0.129 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr15_-_67113909 0.124 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr2_-_33086366 0.119 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr10_+_18469958 0.118 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr10_+_127420334 0.110 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chrM_+_7005 0.101 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr12_+_38781093 0.096 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr10_+_115569986 0.093 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr9_+_61372359 0.091 ENSMUST00000178113.1
ENSMUST00000159386.1
Tle3

transducin-like enhancer of split 3, homolog of Drosophila E(spl)

chr7_+_64501949 0.088 ENSMUST00000138829.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr7_+_64501687 0.081 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr5_+_34999046 0.079 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr13_+_16011851 0.078 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr8_+_4238733 0.075 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr1_-_52190901 0.074 ENSMUST00000156887.1
ENSMUST00000129107.1
Gls

glutaminase

chr13_+_36117349 0.074 ENSMUST00000021857.5
ENSMUST00000099582.2
Fars2

phenylalanine-tRNA synthetase 2 (mitochondrial)

chrM_+_2743 0.072 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr18_-_24603791 0.064 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr4_+_13751297 0.064 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_61364507 0.063 ENSMUST00000049064.2
Rap2b
RAP2B, member of RAS oncogene family
chr6_-_102464667 0.062 ENSMUST00000032159.6
Cntn3
contactin 3
chr12_+_55089202 0.057 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chr2_-_6722187 0.051 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr4_-_97584612 0.051 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr17_+_45734506 0.046 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr7_+_102210335 0.044 ENSMUST00000140631.1
ENSMUST00000120879.1
ENSMUST00000146996.1
Pgap2


post-GPI attachment to proteins 2


chr7_+_25681158 0.042 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr5_-_137531204 0.040 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr8_-_84662841 0.038 ENSMUST00000060427.4
Ier2
immediate early response 2
chr3_+_94413244 0.037 ENSMUST00000166032.1
ENSMUST00000045245.5
Tdrkh

tudor and KH domain containing protein

chr7_+_64502090 0.036 ENSMUST00000137732.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr8_+_4238815 0.036 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr4_+_5724304 0.033 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr5_+_34999070 0.032 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr11_-_97700327 0.025 ENSMUST00000018681.7
Pcgf2
polycomb group ring finger 2
chr1_+_10993452 0.024 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr18_-_24603464 0.023 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr3_+_90600203 0.017 ENSMUST00000001047.7
S100a3
S100 calcium binding protein A3
chr13_-_36117269 0.015 ENSMUST00000053265.6
Lyrm4
LYR motif containing 4
chr7_-_45103747 0.015 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr4_+_154964117 0.011 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr7_+_123123870 0.010 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr16_-_37384915 0.007 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr5_-_137531952 0.006 ENSMUST00000140139.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr4_+_116720920 0.003 ENSMUST00000045542.6
ENSMUST00000106459.1
Tesk2

testis-specific kinase 2


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.9 5.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 3.2 GO:0019532 oxalate transport(GO:0019532)
0.4 1.2 GO:0050975 sensory perception of touch(GO:0050975)
0.4 1.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 1.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 1.8 GO:0016198 axon choice point recognition(GO:0016198)
0.3 1.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 0.8 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 5.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 1.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 3.1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.2 1.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 1.1 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 1.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 1.1 GO:0050957 equilibrioception(GO:0050957)
0.1 0.3 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1 0.3 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.1 0.2 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 2.8 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.2 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.8 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.2 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.3 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) axonogenesis involved in innervation(GO:0060385) facioacoustic ganglion development(GO:1903375)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.8 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 3.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 0.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.6 GO:0060074 synapse maturation(GO:0060074)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 1.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.4 GO:0098792 xenophagy(GO:0098792)
0.0 1.8 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.2 GO:2000249 negative regulation of cell-matrix adhesion(GO:0001953) regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0071953 elastic fiber(GO:0071953)
0.3 3.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.2 GO:0071565 nBAF complex(GO:0071565)
0.1 2.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.5 GO:0043205 fibril(GO:0043205)
0.1 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.1 GO:0031045 dense core granule(GO:0031045)
0.1 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 1.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.8 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.3 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.4 GO:0001618 virus receptor activity(GO:0001618)
0.3 3.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.3 3.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 1.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 1.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 1.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 6.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 2.0 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.2 GO:0046790 virion binding(GO:0046790)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.8 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 1.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0070699 activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699)
0.0 1.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0031690 adrenergic receptor binding(GO:0031690)