Motif ID: Msx2_Hoxd4

Z-value: 0.880

Transcription factors associated with Msx2_Hoxd4:

Gene SymbolEntrez IDGene Name
Msx2 ENSMUSG00000021469.8 Msx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Msx2mm10_v2_chr13_-_53473074_53473074-0.105.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Msx2_Hoxd4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_62766153 13.245 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_62765618 7.116 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_159737510 4.771 ENSMUST00000111669.3
Tnr
tenascin R
chr3_+_62419668 4.405 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr6_-_36811361 4.230 ENSMUST00000101534.1
Ptn
pleiotrophin
chr15_-_37459327 3.166 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr2_-_63184253 3.035 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr1_-_163725123 2.846 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr12_+_74297474 2.751 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr14_-_88471396 2.680 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr12_+_38783503 2.652 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr1_-_190170671 2.105 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr1_+_165788681 2.098 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr3_-_66296807 2.076 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr4_+_136143497 2.013 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr15_+_92597104 1.794 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr1_+_165788746 1.749 ENSMUST00000161559.2
Cd247
CD247 antigen
chr17_-_90088343 1.746 ENSMUST00000173917.1
Nrxn1
neurexin I
chr2_-_63184170 1.640 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr14_+_54259227 1.603 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr15_-_37458523 1.547 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr2_-_144527341 1.524 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr4_-_82850721 1.419 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr11_-_87826023 1.383 ENSMUST00000103177.3
Lpo
lactoperoxidase
chr18_+_4920509 1.343 ENSMUST00000126977.1
Svil
supervillin
chr4_+_102570065 1.311 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr11_-_109472611 1.282 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr5_-_107875035 1.261 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr2_+_4017727 1.250 ENSMUST00000177457.1
Frmd4a
FERM domain containing 4A
chr1_-_190170178 1.238 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr1_+_180109192 1.228 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chrX_+_101640056 1.212 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr15_-_79285502 1.207 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr7_-_73541738 1.202 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr16_-_44016387 1.161 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr6_-_136171722 1.152 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr18_+_52767994 1.091 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr13_+_51408618 1.082 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr3_+_68869563 1.064 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr17_-_25785324 0.982 ENSMUST00000150324.1
Haghl
hydroxyacylglutathione hydrolase-like
chr7_-_73537621 0.979 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr10_+_39612934 0.964 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr3_+_19957037 0.934 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chrX_-_94123359 0.932 ENSMUST00000137853.1
ENSMUST00000088102.5
ENSMUST00000113927.1
Zfx


zinc finger protein X-linked


chr4_-_141078302 0.932 ENSMUST00000030760.8
Necap2
NECAP endocytosis associated 2
chrX_+_56454871 0.902 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr3_-_110143937 0.895 ENSMUST00000051253.3
Ntng1
netrin G1
chr3_-_146495115 0.889 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr3_+_52268337 0.881 ENSMUST00000053764.5
Foxo1
forkhead box O1
chr5_-_146220901 0.880 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
Rnf6



ring finger protein (C3H2C3 type) 6



chr13_-_95250166 0.871 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
Pde8b



phosphodiesterase 8B



chr4_-_40722307 0.824 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr14_-_36919314 0.806 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr11_+_103133303 0.799 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr7_+_97400003 0.784 ENSMUST00000032882.8
Ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr11_+_103133333 0.760 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr1_-_152625212 0.748 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chrX_+_159708593 0.712 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr10_+_75037066 0.709 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr18_+_37513652 0.701 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr5_-_84417359 0.683 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr12_-_85374696 0.674 ENSMUST00000040766.7
Tmed10
transmembrane emp24-like trafficking protein 10 (yeast)
chr10_+_115569986 0.666 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr3_-_85741389 0.643 ENSMUST00000094148.4
Fam160a1
family with sequence similarity 160, member A1
chr2_-_176144697 0.622 ENSMUST00000178872.1
Gm2004
predicted gene 2004
chr1_+_33908172 0.615 ENSMUST00000182513.1
ENSMUST00000183034.1
Dst

dystonin

chr2_-_73453918 0.596 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr2_-_45112890 0.592 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr4_-_129121889 0.590 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr5_-_23616528 0.589 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr1_+_157458554 0.580 ENSMUST00000046743.4
ENSMUST00000119891.1
BC026585

cDNA sequence BC026585

chr7_-_121074501 0.577 ENSMUST00000047194.2
Igsf6
immunoglobulin superfamily, member 6
chr4_-_149126688 0.560 ENSMUST00000030815.2
Cort
cortistatin
chr2_+_109280738 0.554 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chrX_-_8132770 0.539 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
Wdr13



WD repeat domain 13



chr13_+_76098734 0.537 ENSMUST00000091466.3
Ttc37
tetratricopeptide repeat domain 37
chr17_-_46327949 0.534 ENSMUST00000047970.7
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr2_-_45110336 0.525 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr7_-_115824699 0.521 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr15_+_41830921 0.521 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chrX_-_103981242 0.507 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr15_-_50890396 0.495 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr18_+_37518341 0.491 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr9_-_114390633 0.489 ENSMUST00000084881.4
Crtap
cartilage associated protein
chr2_-_33086366 0.477 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr9_+_30942541 0.472 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr2_-_164389095 0.468 ENSMUST00000167427.1
Slpi
secretory leukocyte peptidase inhibitor
chr9_-_55919605 0.468 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr1_-_133661318 0.452 ENSMUST00000027736.6
ENSMUST00000179598.1
Zc3h11a
Zbed6
zinc finger CCCH type containing 11A
zinc finger, BED domain containing 6
chr6_-_124779686 0.446 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr6_-_106800051 0.411 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chrX_-_143933089 0.398 ENSMUST00000087313.3
Dcx
doublecortin
chr12_+_52516077 0.387 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr4_+_124657646 0.382 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr1_+_191025350 0.380 ENSMUST00000181050.1
A230020J21Rik
RIKEN cDNA A230020J21 gene
chrX_-_143933204 0.375 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr9_+_32116040 0.367 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr19_+_26749726 0.366 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_144570687 0.346 ENSMUST00000106211.1
Sep15
selenoprotein
chr11_+_95010277 0.346 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr3_+_138065052 0.327 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr18_+_59062462 0.304 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr1_-_133921393 0.302 ENSMUST00000048432.5
Prelp
proline arginine-rich end leucine-rich repeat
chr18_-_43477764 0.291 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr18_+_37320374 0.286 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr10_-_13324160 0.283 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr7_-_29906524 0.281 ENSMUST00000159920.1
ENSMUST00000162592.1
Zfp27

zinc finger protein 27

chr4_-_148160031 0.278 ENSMUST00000057907.3
Fbxo44
F-box protein 44
chr18_-_37969742 0.247 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr18_-_3281712 0.245 ENSMUST00000182204.1
ENSMUST00000154705.1
ENSMUST00000182833.1
ENSMUST00000151084.1
Crem



cAMP responsive element modulator



chr9_-_71163224 0.226 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr6_+_29361410 0.226 ENSMUST00000156163.1
Calu
calumenin
chr11_-_74724670 0.213 ENSMUST00000021091.8
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr10_-_14718191 0.211 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr3_+_144570409 0.206 ENSMUST00000082437.3
Sep15
selenoprotein
chr7_+_123123870 0.197 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr13_+_75967704 0.174 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chr15_+_21111452 0.152 ENSMUST00000075132.6
Cdh12
cadherin 12
chrM_+_2743 0.140 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr13_-_75943812 0.133 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3

Rho-related BTB domain containing 3

chr1_+_72284367 0.124 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr18_+_34840575 0.122 ENSMUST00000043484.7
Reep2
receptor accessory protein 2
chr4_-_148159838 0.121 ENSMUST00000151127.1
ENSMUST00000105705.2
Fbxo44

F-box protein 44

chr7_+_65693447 0.120 ENSMUST00000143508.1
Tm2d3
TM2 domain containing 3
chr9_-_89705017 0.107 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr9_-_107770945 0.105 ENSMUST00000183248.1
ENSMUST00000182022.1
ENSMUST00000035199.6
ENSMUST00000182659.1
Rbm5



RNA binding motif protein 5



chr1_+_186749368 0.102 ENSMUST00000180869.1
A430105J06Rik
RIKEN cDNA A430105J06 gene
chr17_+_46161021 0.093 ENSMUST00000024748.7
ENSMUST00000172170.1
Gtpbp2

GTP binding protein 2

chr16_+_14705832 0.077 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr10_-_33624587 0.076 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr8_-_70527645 0.071 ENSMUST00000132867.1
Kxd1
KxDL motif containing 1
chr17_-_24073479 0.070 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr6_-_13871477 0.060 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr17_-_14694223 0.052 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr7_+_96522342 0.046 ENSMUST00000129737.1
Tenm4
teneurin transmembrane protein 4
chrM_-_14060 0.044 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr3_+_106113229 0.037 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr2_+_180710117 0.036 ENSMUST00000029090.2
Gid8
GID complex subunit 8 homolog (S. cerevisiae)
chr1_-_172632931 0.023 ENSMUST00000027826.5
Dusp23
dual specificity phosphatase 23
chr9_-_112187766 0.022 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_-_31179901 0.013 ENSMUST00000101411.2
ENSMUST00000140793.1
Gtf3c2

general transcription factor IIIC, polypeptide 2, beta

chr7_-_101845300 0.013 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chr6_+_136518820 0.009 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr6_+_37870786 0.004 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.4 4.2 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
1.1 3.3 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.5 1.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 1.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.7 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 0.9 GO:0035106 operant conditioning(GO:0035106)
0.2 0.7 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 4.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 0.6 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.2 1.1 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 0.9 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 1.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 1.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 2.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 0.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 0.9 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.1 0.5 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 1.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 2.8 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 2.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 2.0 GO:0071398 cellular response to fatty acid(GO:0071398)
0.1 1.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.9 GO:0046688 response to copper ion(GO:0046688)
0.1 1.0 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 1.4 GO:0007097 nuclear migration(GO:0007097)
0.1 0.9 GO:0060746 parental behavior(GO:0060746)
0.1 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 3.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.0 GO:0001783 B cell apoptotic process(GO:0001783)
0.1 0.6 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 4.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0046689 response to mercury ion(GO:0046689)
0.0 1.1 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 1.6 GO:0019915 lipid storage(GO:0019915)
0.0 4.7 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 1.0 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.0 1.5 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0072534 perineuronal net(GO:0072534)
1.0 3.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 0.5 GO:0055087 Ski complex(GO:0055087)
0.2 0.6 GO:0031673 H zone(GO:0031673)
0.1 1.2 GO:0070688 MLL5-L complex(GO:0070688)
0.1 1.2 GO:0071439 clathrin complex(GO:0071439)
0.1 1.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 4.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.9 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 1.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0000346 transcription export complex(GO:0000346)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 21.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.4 3.3 GO:0050693 LBD domain binding(GO:0050693)
0.3 4.8 GO:0046625 sphingolipid binding(GO:0046625)
0.2 4.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 1.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 4.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 1.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 2.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.6 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.4 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.8 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 2.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.6 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.4 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.1 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)