Motif ID: Mtf1

Z-value: 1.451


Transcription factors associated with Mtf1:

Gene SymbolEntrez IDGene Name
Mtf1 ENSMUSG00000028890.7 Mtf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mtf1mm10_v2_chr4_+_124802543_1248026780.531.5e-03Click!


Activity profile for motif Mtf1.

activity profile for motif Mtf1


Sorted Z-values histogram for motif Mtf1

Sorted Z-values for motif Mtf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mtf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 83 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_94172618 30.229 ENSMUST00000034214.6
 Mt2
metallothionein 2
chr8_+_94179089 19.181 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr11_-_32222233 11.658 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr11_+_63133068 10.582 ENSMUST00000108700.1
 Pmp22
peripheral myelin protein 22
chr11_+_63132569 9.995 ENSMUST00000108701.1
 Pmp22
peripheral myelin protein 22
chr1_+_191906743 7.423 ENSMUST00000044954.6
 Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr1_+_135729147 6.860 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr4_+_134496996 5.541 ENSMUST00000095074.3
 Paqr7
progestin and adipoQ receptor family member VII
chr6_-_39118211 5.490 ENSMUST00000038398.6
 Parp12
poly (ADP-ribose) polymerase family, member 12
chr12_+_24572276 4.730 ENSMUST00000085553.5
 Grhl1
grainyhead-like 1 (Drosophila)
chr14_-_26170283 4.497 ENSMUST00000100809.4
 Plac9b
placenta specific 9b
chr5_+_105415738 4.411 ENSMUST00000112707.1
 Lrrc8b
leucine rich repeat containing 8 family, member B
chr9_-_14381242 3.676 ENSMUST00000167549.1
 Endod1
endonuclease domain containing 1
chr4_+_129984833 3.192 ENSMUST00000120204.1
 Bai2
brain-specific angiogenesis inhibitor 2
chr4_+_129985098 3.101 ENSMUST00000106017.1
ENSMUST00000121049.1
 Bai2

brain-specific angiogenesis inhibitor 2

chr8_-_54529951 2.904 ENSMUST00000067476.8
 Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr1_-_166002613 2.864 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
 Pou2f1



POU domain, class 2, transcription factor 1



chr9_-_56635624 2.579 ENSMUST00000114256.1
 Lingo1
leucine rich repeat and Ig domain containing 1
chr10_+_70245083 2.579 ENSMUST00000046807.6
 Slc16a9
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr3_-_121815212 2.534 ENSMUST00000029770.5
 Abcd3
ATP-binding cassette, sub-family D (ALD), member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.1 56.8 GO:0061687 detoxification of inorganic compound(GO:0061687)
1.1 20.6 GO:0032060 bleb assembly(GO:0032060)
0.2 11.7 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1 6.9 GO:0070527 platelet aggregation(GO:0070527)
0.1 5.5 GO:0048477 oogenesis(GO:0048477)
0.7 5.2 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.8 4.7 GO:0002934 desmosome organization(GO:0002934)
0.0 4.4 GO:0098656 anion transmembrane transport(GO:0098656)
0.5 3.7 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.3 2.6 GO:0046415 urate metabolic process(GO:0046415)
0.1 2.6 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.8 2.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.3 2.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 2.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.7 2.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 1.8 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.6 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.5 1.5 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.0 1.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 1.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 20.6 GO:0043218 compact myelin(GO:0043218)
0.0 17.7 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 11.7 GO:0000139 Golgi membrane(GO:0000139)
0.1 7.4 GO:0030315 T-tubule(GO:0030315)
0.0 7.3 GO:0005925 focal adhesion(GO:0005925)
0.0 5.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.3 3.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 2.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.7 2.0 GO:0044194 cytolytic granule(GO:0044194)
0.2 1.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.9 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 38.0 GO:0008270 zinc ion binding(GO:0008270)
0.4 20.3 GO:0005507 copper ion binding(GO:0005507)
0.1 11.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.5 7.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 5.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 5.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 4.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 3.7 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 3.1 GO:0004519 endonuclease activity(GO:0004519)
0.1 2.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.5 2.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 2.2 GO:0034046 poly(G) binding(GO:0034046)
0.2 2.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 2.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 2.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.5 1.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.6 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) NADPH:sulfur oxidoreductase activity(GO:0043914) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.4 GO:0042169 SH2 domain binding(GO:0042169)