Motif ID: Mybl1

Z-value: 1.205


Transcription factors associated with Mybl1:

Gene SymbolEntrez IDGene Name
Mybl1 ENSMUSG00000025912.10 Mybl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl1mm10_v2_chr1_-_9700209_9700329-0.467.7e-03Click!


Activity profile for motif Mybl1.

activity profile for motif Mybl1


Sorted Z-values histogram for motif Mybl1

Sorted Z-values for motif Mybl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mybl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_32276400 7.018 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_-_69921190 5.401 ENSMUST00000108607.1
 Eif5a
eukaryotic translation initiation factor 5A
chr14_-_48662740 5.348 ENSMUST00000122009.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chrX_-_106485214 4.392 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr9_+_78191966 4.135 ENSMUST00000034903.5
 Gsta4
glutathione S-transferase, alpha 4
chr8_+_83715504 3.996 ENSMUST00000109810.1
 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr11_-_106999369 3.567 ENSMUST00000106768.1
ENSMUST00000144834.1
 Kpna2

karyopherin (importin) alpha 2

chr11_+_59306920 3.506 ENSMUST00000000128.3
ENSMUST00000108783.3
 Wnt9a

wingless-type MMTV integration site 9A

chr7_+_126862431 3.464 ENSMUST00000132808.1
 Hirip3
HIRA interacting protein 3
chr11_-_69921329 3.214 ENSMUST00000108613.3
ENSMUST00000043419.3
ENSMUST00000070996.4
 Eif5a


eukaryotic translation initiation factor 5A


chr4_+_65124174 3.150 ENSMUST00000084501.3
 Pappa
pregnancy-associated plasma protein A
chr2_+_174450678 3.041 ENSMUST00000016399.5
 Tubb1
tubulin, beta 1 class VI
chr6_+_30723541 3.038 ENSMUST00000115127.1
 Mest
mesoderm specific transcript
chr2_+_118814195 2.989 ENSMUST00000110842.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding
chr11_+_32296489 2.981 ENSMUST00000093207.3
 Hba-a2
hemoglobin alpha, adult chain 2
chr8_+_83715177 2.936 ENSMUST00000019576.8
 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr2_+_118814237 2.895 ENSMUST00000028803.7
ENSMUST00000126045.1
 Knstrn

kinetochore-localized astrin/SPAG5 binding

chr11_-_106999482 2.893 ENSMUST00000018506.6
 Kpna2
karyopherin (importin) alpha 2
chr15_-_60824942 2.827 ENSMUST00000100635.3
 Fam84b
family with sequence similarity 84, member B
chr7_+_144915100 2.755 ENSMUST00000128057.1
 Oraov1
oral cancer overexpressed 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 278 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 13.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 10.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 8.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 7.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
1.4 7.0 GO:0015671 oxygen transport(GO:0015671)
0.0 5.9 GO:0007067 mitotic nuclear division(GO:0007067)
1.3 5.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.6 4.8 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
1.2 4.8 GO:0042360 vitamin E metabolic process(GO:0042360)
0.9 4.3 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.7 4.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.8 4.0 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.5 3.7 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 3.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.3 3.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.4 3.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.4 3.5 GO:0044458 motile cilium assembly(GO:0044458)
0.8 3.4 GO:0003360 brainstem development(GO:0003360)
0.0 3.3 GO:0051225 spindle assembly(GO:0051225)
0.2 3.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 147 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 14.4 GO:0005642 annulate lamellae(GO:0005642)
0.2 13.3 GO:0005643 nuclear pore(GO:0005643)
0.1 12.7 GO:0005681 spliceosomal complex(GO:0005681)
1.2 10.0 GO:0005833 hemoglobin complex(GO:0005833)
0.0 9.9 GO:0005615 extracellular space(GO:0005615)
0.3 9.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 6.5 GO:0005730 nucleolus(GO:0005730)
0.0 5.7 GO:0005925 focal adhesion(GO:0005925)
0.2 5.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 4.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 4.8 GO:0005635 nuclear envelope(GO:0005635)
0.2 4.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 4.2 GO:0035861 site of double-strand break(GO:0035861)
0.2 3.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.9 GO:0000776 kinetochore(GO:0000776)
0.1 3.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
1.1 3.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 3.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 2.8 GO:0030896 checkpoint clamp complex(GO:0030896)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 196 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.1 14.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 11.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.4 10.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 8.4 GO:0003735 structural constituent of ribosome(GO:0003735)
1.4 7.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.7 4.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 4.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 4.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.7 3.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.7 3.5 GO:0032027 myosin light chain binding(GO:0032027)
0.6 3.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.2 3.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 3.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 3.2 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.1 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 3.2 GO:0003682 chromatin binding(GO:0003682)
0.7 3.0 GO:0031720 haptoglobin binding(GO:0031720)
0.1 2.8 GO:0005109 frizzled binding(GO:0005109)