Motif ID: Mybl2

Z-value: 1.327


Transcription factors associated with Mybl2:

Gene SymbolEntrez IDGene Name
Mybl2 ENSMUSG00000017861.5 Mybl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl2mm10_v2_chr2_+_163054682_1630546930.855.4e-10Click!


Activity profile for motif Mybl2.

activity profile for motif Mybl2


Sorted Z-values histogram for motif Mybl2

Sorted Z-values for motif Mybl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mybl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_90002881 6.634 ENSMUST00000020864.8
 Pctp
phosphatidylcholine transfer protein
chr9_-_79977782 4.769 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr18_-_60624304 4.753 ENSMUST00000097566.3
 Synpo
synaptopodin
chr11_-_106999369 4.684 ENSMUST00000106768.1
ENSMUST00000144834.1
 Kpna2

karyopherin (importin) alpha 2

chrX_-_143827391 4.412 ENSMUST00000087316.5
 Capn6
calpain 6
chr19_-_41802028 4.291 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
 Arhgap19


Rho GTPase activating protein 19


chr8_+_83715504 3.781 ENSMUST00000109810.1
 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr13_-_81710937 3.777 ENSMUST00000161920.1
ENSMUST00000048993.5
 Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr1_-_169531343 3.659 ENSMUST00000028000.7
 Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_+_46847128 3.538 ENSMUST00000005051.4
 Ldha
lactate dehydrogenase A
chr11_-_106999482 3.520 ENSMUST00000018506.6
 Kpna2
karyopherin (importin) alpha 2
chr8_+_117498272 3.158 ENSMUST00000081232.7
 Plcg2
phospholipase C, gamma 2
chr15_-_13173607 3.130 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr19_+_53142756 3.122 ENSMUST00000050096.7
 Add3
adducin 3 (gamma)
chr1_-_169531447 3.113 ENSMUST00000111368.1
 Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr13_+_92354783 3.057 ENSMUST00000022218.4
 Dhfr
dihydrofolate reductase
chr2_-_75981967 3.051 ENSMUST00000099994.3
 Ttc30a1
tetratricopeptide repeat domain 30A1
chr2_+_13573927 3.047 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr9_+_92250039 3.030 ENSMUST00000093801.3
 Plscr1
phospholipid scramblase 1
chr18_+_5591860 2.935 ENSMUST00000025081.5
ENSMUST00000159390.1
 Zeb1

zinc finger E-box binding homeobox 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 181 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 6.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 6.6 GO:0015914 phospholipid transport(GO:0015914)
1.1 5.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 5.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.2 4.8 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 4.8 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.9 4.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.5 4.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 4.0 GO:0043486 histone exchange(GO:0043486)
0.3 3.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 3.6 GO:0070836 caveola assembly(GO:0070836)
0.7 3.5 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3 3.4 GO:0019985 translesion synthesis(GO:0019985)
0.6 3.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 3.2 GO:0007219 Notch signaling pathway(GO:0007219)
0.8 3.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 3.1 GO:0042073 intraciliary transport(GO:0042073)
0.0 3.1 GO:0042493 response to drug(GO:0042493)
1.0 3.0 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.2 GO:0000793 condensed chromosome(GO:0000793)
1.4 8.6 GO:0031262 Ndc80 complex(GO:0031262)
0.1 7.5 GO:0005643 nuclear pore(GO:0005643)
0.0 6.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 5.5 GO:0005635 nuclear envelope(GO:0005635)
0.4 5.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 5.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 5.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 5.2 GO:0005871 kinesin complex(GO:0005871)
0.0 4.9 GO:0005912 adherens junction(GO:0005912)
0.2 4.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 4.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 4.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 4.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.4 3.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 3.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.8 3.0 GO:0045098 type III intermediate filament(GO:0045098)
0.3 3.0 GO:0061574 ASAP complex(GO:0061574)
0.1 3.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.6 2.8 GO:0032133 chromosome passenger complex(GO:0032133)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 141 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
1.1 6.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 6.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 5.2 GO:0003777 microtubule motor activity(GO:0003777)
0.3 4.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 4.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 4.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 3.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 3.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.9 3.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.0 3.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 3.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 3.1 GO:0042393 histone binding(GO:0042393)
0.8 3.0 GO:1990254 keratin filament binding(GO:1990254)
0.8 3.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.4 3.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 3.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 2.9 GO:0016594 glycine binding(GO:0016594)
0.1 2.9 GO:0070888 E-box binding(GO:0070888)
0.4 2.8 GO:0034452 dynactin binding(GO:0034452)