Motif ID: Neurod1

Z-value: 1.750


Transcription factors associated with Neurod1:

Gene SymbolEntrez IDGene Name
Neurod1 ENSMUSG00000034701.9 Neurod1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurod1mm10_v2_chr2_-_79456750_794567610.823.7e-09Click!


Activity profile for motif Neurod1.

activity profile for motif Neurod1


Sorted Z-values histogram for motif Neurod1

Sorted Z-values for motif Neurod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 30.889 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr11_-_98329641 23.789 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr5_-_142608785 16.907 ENSMUST00000037048.7
 Mmd2
monocyte to macrophage differentiation-associated 2
chr12_+_29528382 13.739 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr15_-_99705490 13.694 ENSMUST00000163472.2
 Gm17349
predicted gene, 17349
chr16_+_42907563 13.600 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr2_-_29253001 12.751 ENSMUST00000071201.4
 Ntng2
netrin G2
chr18_+_45268876 12.696 ENSMUST00000183850.1
ENSMUST00000066890.7
 Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr11_+_32000452 12.359 ENSMUST00000020537.2
ENSMUST00000109409.1
 Nsg2

neuron specific gene family member 2

chr1_+_9601163 10.775 ENSMUST00000088666.3
 3110035E14Rik
RIKEN cDNA 3110035E14 gene
chr3_+_18054258 10.675 ENSMUST00000026120.6
 Bhlhe22
basic helix-loop-helix family, member e22
chr3_-_84259812 10.441 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr2_-_25319095 10.230 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
 Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr16_-_67620880 9.777 ENSMUST00000114292.1
ENSMUST00000120898.1
 Cadm2

cell adhesion molecule 2

chr2_+_90885860 9.665 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr11_-_107915041 9.177 ENSMUST00000039071.2
 Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr11_+_32000496 8.969 ENSMUST00000093219.3
 Nsg2
neuron specific gene family member 2
chr6_+_54681687 8.774 ENSMUST00000046276.6
 2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr6_-_136171722 8.446 ENSMUST00000053880.6
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr10_+_69706326 7.960 ENSMUST00000182992.1
 Ank3
ankyrin 3, epithelial

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 36.9 GO:0021542 dentate gyrus development(GO:0021542)
7.9 23.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 21.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.0 21.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.8 16.9 GO:0019835 cytolysis(GO:0019835)
0.9 14.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.4 13.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.5 13.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 12.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.4 11.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 11.2 GO:0050808 synapse organization(GO:0050808)
3.7 11.0 GO:1900673 olefin metabolic process(GO:1900673)
0.1 10.9 GO:1900006 positive regulation of dendrite development(GO:1900006)
1.8 10.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.5 9.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 8.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.7 8.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.0 7.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.8 7.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.7 7.5 GO:0032482 Rab protein signal transduction(GO:0032482)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 26.0 GO:0060076 excitatory synapse(GO:0060076)
0.6 19.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 15.2 GO:0045211 postsynaptic membrane(GO:0045211)
1.0 14.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.6 13.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 12.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.4 11.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 11.1 GO:0000788 nuclear nucleosome(GO:0000788)
2.7 11.0 GO:0044307 dendritic branch(GO:0044307)
0.2 11.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.8 10.7 GO:0042788 polysomal ribosome(GO:0042788)
0.0 10.4 GO:0005768 endosome(GO:0005768)
0.1 9.8 GO:0055037 recycling endosome(GO:0055037)
0.2 9.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 9.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 8.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.9 7.4 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 7.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.4 6.9 GO:0042101 T cell receptor complex(GO:0042101)
0.4 5.3 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 22.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
3.6 21.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 21.3 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 21.2 GO:0004672 protein kinase activity(GO:0004672)
0.5 20.6 GO:0070888 E-box binding(GO:0070888)
0.1 14.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.9 13.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 13.1 GO:0042393 histone binding(GO:0042393)
3.2 12.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 12.5 GO:0017022 myosin binding(GO:0017022)
0.4 12.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 11.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 10.9 GO:0017091 AU-rich element binding(GO:0017091)
0.8 9.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.3 9.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 8.8 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 8.5 GO:0003714 transcription corepressor activity(GO:0003714)
1.0 8.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.6 7.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.9 7.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)