Motif ID: Neurod2_Bhlha15_Bhlhe22_Olig1

Z-value: 0.832

Transcription factors associated with Neurod2_Bhlha15_Bhlhe22_Olig1:

Gene SymbolEntrez IDGene Name
Bhlha15 ENSMUSG00000052271.7 Bhlha15
Bhlhe22 ENSMUSG00000025128.6 Bhlhe22
Neurod2 ENSMUSG00000038255.6 Neurod2
Olig1 ENSMUSG00000046160.5 Olig1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe22mm10_v2_chr3_+_18054258_180543250.826.9e-09Click!
Neurod2mm10_v2_chr11_-_98329641_983296540.756.2e-07Click!
Olig1mm10_v2_chr16_+_91269759_91269778-0.232.0e-01Click!


Activity profile for motif Neurod2_Bhlha15_Bhlhe22_Olig1.

activity profile for motif Neurod2_Bhlha15_Bhlhe22_Olig1


Sorted Z-values histogram for motif Neurod2_Bhlha15_Bhlhe22_Olig1

Sorted Z-values for motif Neurod2_Bhlha15_Bhlhe22_Olig1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod2_Bhlha15_Bhlhe22_Olig1

PNG image of the network

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Top targets:


Showing 1 to 20 of 164 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_98329641 8.266 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr1_+_177444653 7.724 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr3_-_120886691 6.040 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
 6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr2_-_79456750 5.783 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr11_+_58954675 5.762 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr9_-_21918089 4.815 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
 Rab3d



RAB3D, member RAS oncogene family



chr1_+_177445660 3.961 ENSMUST00000077225.6
 Zbtb18
zinc finger and BTB domain containing 18
chr2_+_65930117 3.763 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr17_-_36989504 3.665 ENSMUST00000169189.1
 H2-M5
histocompatibility 2, M region locus 5
chr5_-_66618772 3.322 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
 Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr1_-_44218952 3.232 ENSMUST00000054801.3
 Mettl21e
methyltransferase like 21E
chr1_-_150392719 2.783 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr1_+_150392794 2.774 ENSMUST00000124973.2
 Tpr
translocated promoter region
chr4_-_110292719 2.725 ENSMUST00000106601.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_+_124194894 2.657 ENSMUST00000159053.1
ENSMUST00000162577.1
 Gm16338

predicted gene 16338

chr1_-_111864869 2.360 ENSMUST00000035462.5
 Dsel
dermatan sulfate epimerase-like
chr2_+_155382186 2.017 ENSMUST00000134218.1
 Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr5_-_103977360 1.861 ENSMUST00000048118.8
 Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr2_+_69670100 1.858 ENSMUST00000100050.3
 Klhl41
kelch-like 41
chr4_-_141598206 1.832 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
 Fblim1


filamin binding LIM protein 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 13.4 GO:0021766 hippocampus development(GO:0021766)
2.8 8.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 6.2 GO:0007050 cell cycle arrest(GO:0007050)
1.4 5.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.4 5.8 GO:0070914 UV-damage excision repair(GO:0070914)
1.0 4.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.7 3.9 GO:0032796 uropod organization(GO:0032796)
0.0 3.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 3.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 3.5 GO:0032259 methylation(GO:0032259)
0.9 2.8 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 2.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.6 2.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5 2.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 2.0 GO:0000045 autophagosome assembly(GO:0000045)
0.2 1.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.9 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 1.9 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.1 1.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.8 GO:0070734 histone H3-K27 methylation(GO:0070734)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 11.7 GO:0045171 intercellular bridge(GO:0045171)
0.2 5.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 4.8 GO:0042588 zymogen granule(GO:0042588)
0.2 3.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 2.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.6 2.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 2.8 GO:0042788 polysomal ribosome(GO:0042788)
0.5 2.7 GO:0097441 basilar dendrite(GO:0097441)
0.0 2.0 GO:0005776 autophagosome(GO:0005776)
0.1 1.9 GO:0031143 pseudopodium(GO:0031143)
0.1 1.9 GO:0071564 npBAF complex(GO:0071564)
0.0 1.9 GO:0005811 lipid particle(GO:0005811)
0.1 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.7 GO:0031201 SNARE complex(GO:0031201)
0.1 1.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.5 GO:0070888 E-box binding(GO:0070888)
0.0 6.3 GO:0030674 protein binding, bridging(GO:0030674)
0.1 5.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 4.8 GO:0031489 myosin V binding(GO:0031489)
0.4 3.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 3.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 3.2 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.2 2.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.6 2.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.7 GO:0015293 symporter activity(GO:0015293)
0.1 2.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 1.9 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0 1.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 1.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.8 GO:0031005 filamin binding(GO:0031005)
0.1 1.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)