Motif ID: Nfat5

Z-value: 1.028


Transcription factors associated with Nfat5:

Gene SymbolEntrez IDGene Name
Nfat5 ENSMUSG00000003847.10 Nfat5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfat5mm10_v2_chr8_+_107293463_1072934830.336.0e-02Click!


Activity profile for motif Nfat5.

activity profile for motif Nfat5


Sorted Z-values histogram for motif Nfat5

Sorted Z-values for motif Nfat5



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfat5

PNG image of the network

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Top targets:


Showing 1 to 20 of 78 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_97417730 6.670 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr6_+_120773633 6.126 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr9_+_92457369 5.573 ENSMUST00000034941.7
 Plscr4
phospholipid scramblase 4
chr6_-_58907120 5.095 ENSMUST00000059539.3
 Nap1l5
nucleosome assembly protein 1-like 5
chr5_+_139423151 4.349 ENSMUST00000066211.4
 Gper1
G protein-coupled estrogen receptor 1
chr7_+_110773658 3.859 ENSMUST00000143786.1
 Ampd3
adenosine monophosphate deaminase 3
chr8_-_107403197 3.837 ENSMUST00000003947.8
 Nqo1
NAD(P)H dehydrogenase, quinone 1
chr1_+_24678536 3.826 ENSMUST00000095062.3
 Lmbrd1
LMBR1 domain containing 1
chr5_-_104021919 3.297 ENSMUST00000031251.9
 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr7_+_110774240 3.134 ENSMUST00000147587.1
 Ampd3
adenosine monophosphate deaminase 3
chrX_-_155216338 3.107 ENSMUST00000112551.3
 Sat1
spermidine/spermine N1-acetyl transferase 1
chr14_-_101609033 3.059 ENSMUST00000161991.1
ENSMUST00000100340.3
 Tbc1d4

TBC1 domain family, member 4

chr6_-_101377897 2.975 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr19_+_25236959 2.969 ENSMUST00000049400.8
 Kank1
KN motif and ankyrin repeat domains 1
chr9_-_29963112 2.847 ENSMUST00000075069.4
 Ntm
neurotrimin
chr15_-_75894474 2.718 ENSMUST00000023237.6
 Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr19_-_5845471 2.696 ENSMUST00000174287.1
ENSMUST00000173672.1
 Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr5_-_104021799 2.686 ENSMUST00000119025.1
 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chrX_-_155216444 2.575 ENSMUST00000026318.8
 Sat1
spermidine/spermine N1-acetyl transferase 1
chr3_-_27710413 2.392 ENSMUST00000046157.4
 Fndc3b
fibronectin type III domain containing 3B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.9 7.0 GO:0032264 IMP salvage(GO:0032264)
0.2 6.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.6 6.0 GO:0042447 hormone catabolic process(GO:0042447)
1.9 5.7 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 5.1 GO:0006334 nucleosome assembly(GO:0006334)
1.4 4.3 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.2 4.3 GO:0046325 negative regulation of glucose import(GO:0046325)
1.1 4.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 4.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.6 4.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 3.8 GO:0006801 superoxide metabolic process(GO:0006801)
0.3 3.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
1.0 3.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 3.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.2 2.7 GO:0030575 nuclear body organization(GO:0030575)
0.2 2.6 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 2.5 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.3 2.4 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.7 2.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 GO:0005811 lipid particle(GO:0005811)
0.0 5.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.4 4.3 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.2 4.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 4.1 GO:0031143 pseudopodium(GO:0031143)
0.2 3.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.3 2.7 GO:0042382 paraspeckles(GO:0042382)
0.0 2.3 GO:0030315 T-tubule(GO:0030315)
0.0 2.2 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 1.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
1.0 7.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.9 6.0 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
1.9 5.7 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.7 5.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 5.3 GO:0015293 symporter activity(GO:0015293)
0.8 4.8 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 4.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.5 4.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 4.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.4 4.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.0 3.8 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 3.8 GO:0031419 cobalamin binding(GO:0031419)
0.0 3.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.6 2.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.5 2.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 1.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.7 GO:0034711 inhibin binding(GO:0034711)
0.2 1.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)