Motif ID: Nfatc2

Z-value: 1.207


Transcription factors associated with Nfatc2:

Gene SymbolEntrez IDGene Name
Nfatc2 ENSMUSG00000027544.10 Nfatc2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc2mm10_v2_chr2_-_168590315_1685903720.299.7e-02Click!


Activity profile for motif Nfatc2.

activity profile for motif Nfatc2


Sorted Z-values histogram for motif Nfatc2

Sorted Z-values for motif Nfatc2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_61185558 10.455 ENSMUST00000166381.1
 Cdr1
cerebellar degeneration related antigen 1
chr19_-_5796924 6.377 ENSMUST00000174808.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr19_-_5797410 4.168 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr12_+_29528382 3.990 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr3_-_80802789 3.954 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr11_+_31872100 3.810 ENSMUST00000020543.6
ENSMUST00000109412.2
 Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr14_+_75955003 3.798 ENSMUST00000050120.2
 Kctd4
potassium channel tetramerisation domain containing 4
chr9_+_3027439 3.731 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3000922 3.557 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chrX_-_143933089 3.521 ENSMUST00000087313.3
 Dcx
doublecortin
chr9_+_3037111 3.386 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3023547 3.252 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3013140 3.198 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr9_+_3004457 3.168 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3036877 3.107 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr2_+_98662227 2.964 ENSMUST00000099684.3
 Gm10801
predicted gene 10801
chr9_+_3034599 2.795 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr17_-_91088726 2.724 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
 Nrxn1



neurexin I



chr9_+_3017408 2.678 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr2_-_98667264 2.670 ENSMUST00000099683.1
 Gm10800
predicted gene 10800

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 270 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 10.5 GO:0035063 nuclear speck organization(GO:0035063)
0.4 8.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 6.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 6.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 5.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.3 5.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 3.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 3.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.3 3.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 3.2 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.2 3.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6 2.9 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.5 2.7 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 2.6 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 2.6 GO:0032060 bleb assembly(GO:0032060)
0.1 2.5 GO:0097320 membrane tubulation(GO:0097320)
0.3 2.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.5 2.3 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.4 2.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 2.3 GO:0007612 learning(GO:0007612)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.9 GO:0016607 nuclear speck(GO:0016607)
0.1 6.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 5.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 4.2 GO:0005614 interstitial matrix(GO:0005614)
0.2 4.0 GO:0032279 asymmetric synapse(GO:0032279)
0.2 3.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 3.8 GO:0071565 nBAF complex(GO:0071565)
0.1 3.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 3.6 GO:0043197 dendritic spine(GO:0043197)
0.0 3.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.6 GO:0005874 microtubule(GO:0005874)
0.1 2.9 GO:0014704 intercalated disc(GO:0014704)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.8 GO:0043194 axon initial segment(GO:0043194)
0.3 2.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.5 GO:0042734 presynaptic membrane(GO:0042734)
0.2 2.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 2.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.2 2.2 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.9 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 168 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 4.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 4.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.7 3.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 3.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.9 3.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 3.1 GO:0043422 protein kinase B binding(GO:0043422)
0.3 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 3.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.8 GO:0005096 GTPase activator activity(GO:0005096)
0.3 2.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.5 GO:0017091 AU-rich element binding(GO:0017091)
0.2 2.4 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 2.3 GO:0017124 SH3 domain binding(GO:0017124)
0.5 2.2 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.1 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 1.9 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)