Motif ID: Nfatc3

Z-value: 1.337


Transcription factors associated with Nfatc3:

Gene SymbolEntrez IDGene Name
Nfatc3 ENSMUSG00000031902.9 Nfatc3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc3mm10_v2_chr8_+_106059562_1060596230.327.1e-02Click!


Activity profile for motif Nfatc3.

activity profile for motif Nfatc3


Sorted Z-values histogram for motif Nfatc3

Sorted Z-values for motif Nfatc3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_80713062 10.263 ENSMUST00000170905.1
ENSMUST00000078049.4
 Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr17_-_49564262 7.390 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr1_-_162866502 7.101 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr19_+_58670358 7.014 ENSMUST00000057270.7
 Pnlip
pancreatic lipase
chr15_-_79164477 5.943 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr11_+_63133068 5.000 ENSMUST00000108700.1
 Pmp22
peripheral myelin protein 22
chr1_-_170110491 4.791 ENSMUST00000027985.2
 Ddr2
discoidin domain receptor family, member 2
chr15_+_3270767 4.254 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr11_+_63132569 4.139 ENSMUST00000108701.1
 Pmp22
peripheral myelin protein 22
chr5_-_62765618 4.045 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_120773633 3.760 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr7_-_134232125 3.442 ENSMUST00000127524.1
 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr7_-_134232005 3.383 ENSMUST00000134504.1
 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_+_12718496 3.371 ENSMUST00000088585.3
 Sulf1
sulfatase 1
chr9_-_58158498 3.279 ENSMUST00000168864.2
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr1_-_66863265 3.025 ENSMUST00000027153.5
 Acadl
acyl-Coenzyme A dehydrogenase, long-chain
chr19_-_5845471 2.966 ENSMUST00000174287.1
ENSMUST00000173672.1
 Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr5_-_70842617 2.886 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chrX_-_155216444 2.855 ENSMUST00000026318.8
 Sat1
spermidine/spermine N1-acetyl transferase 1
chr5_-_51567717 2.841 ENSMUST00000127135.1
ENSMUST00000151104.1
 Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 136 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.4 10.3 GO:0060854 patterning of lymph vessels(GO:0060854)
0.5 9.1 GO:0032060 bleb assembly(GO:0032060)
0.1 7.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.7 7.1 GO:0009404 toxin metabolic process(GO:0009404)
1.2 7.0 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.5 5.9 GO:0048484 enteric nervous system development(GO:0048484)
1.9 5.6 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.8 5.3 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.7 4.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 4.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.6 4.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.7 3.5 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.8 3.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 3.2 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 2.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.9 2.8 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.5 2.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.5 2.8 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.3 2.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 2.7 GO:0001913 T cell mediated cytotoxicity(GO:0001913)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.6 GO:0005667 transcription factor complex(GO:0005667)
0.4 9.1 GO:0043218 compact myelin(GO:0043218)
0.8 6.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 6.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 5.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 4.1 GO:0016324 apical plasma membrane(GO:0016324)
0.4 3.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.4 3.0 GO:0042382 paraspeckles(GO:0042382)
0.2 2.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 2.8 GO:0097440 apical dendrite(GO:0097440)
0.3 2.6 GO:0030478 actin cap(GO:0030478)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 2.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.4 GO:0031143 pseudopodium(GO:0031143)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.0 2.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.1 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 10.3 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.1 8.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
1.4 7.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 7.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 5.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.9 5.6 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 5.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.5 4.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 4.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.7 3.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 3.4 GO:0051015 actin filament binding(GO:0051015)
0.2 3.2 GO:0008430 selenium binding(GO:0008430)
0.0 3.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.1 GO:0015293 symporter activity(GO:0015293)
0.5 3.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 3.0 GO:0005096 GTPase activator activity(GO:0005096)
0.2 2.9 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.7 2.8 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 2.8 GO:0008253 5'-nucleotidase activity(GO:0008253)