Motif ID: Nfatc4

Z-value: 0.574


Transcription factors associated with Nfatc4:

Gene SymbolEntrez IDGene Name
Nfatc4 ENSMUSG00000023411.5 Nfatc4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc4mm10_v2_chr14_+_55824795_55824889-0.392.5e-02Click!


Activity profile for motif Nfatc4.

activity profile for motif Nfatc4


Sorted Z-values histogram for motif Nfatc4

Sorted Z-values for motif Nfatc4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc4

PNG image of the network

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Top targets:


Showing 1 to 20 of 59 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_56978534 4.298 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr4_+_48049080 3.088 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr13_+_83504032 2.969 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr1_-_56969864 2.753 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr19_+_26623419 2.731 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_-_4943049 2.505 ENSMUST00000133254.1
ENSMUST00000120475.1
ENSMUST00000025834.7
Peli3


pellino 3


chr2_+_55435918 1.689 ENSMUST00000067101.3
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr2_-_66410064 1.449 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr11_+_97415527 1.388 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr5_+_117363513 1.183 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr19_-_8839181 1.145 ENSMUST00000096259.4
Gng3
guanine nucleotide binding protein (G protein), gamma 3
chr13_-_52981027 1.012 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr1_-_126830632 0.994 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr9_+_113812547 0.982 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr6_-_59024470 0.910 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr14_+_70555900 0.850 ENSMUST00000163060.1
Hr
hairless
chrX_+_7638674 0.808 ENSMUST00000128890.1
Syp
synaptophysin
chr12_+_76533540 0.793 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_-_13446753 0.748 ENSMUST00000167906.2
Gm17571
predicted gene, 17571
chr1_-_193370225 0.744 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.0 3.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.0 3.0 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.3 2.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.8 2.5 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 1.7 GO:0010107 potassium ion import(GO:0010107)
0.1 1.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
0.1 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.0 GO:0016607 nuclear speck(GO:0016607)
0.1 2.7 GO:0071564 npBAF complex(GO:0071564)
0.1 1.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 1.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.1 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 0.7 GO:0031673 H zone(GO:0031673)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.0 GO:0003680 AT DNA binding(GO:0003680)
0.2 2.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.4 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)