Motif ID: Nfe2_Bach1_Mafk

Z-value: 0.600

Transcription factors associated with Nfe2_Bach1_Mafk:

Gene SymbolEntrez IDGene Name
Bach1 ENSMUSG00000025612.5 Bach1
Mafk ENSMUSG00000018143.4 Mafk
Nfe2 ENSMUSG00000058794.6 Nfe2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bach1mm10_v2_chr16_+_87698904_876989590.638.4e-05Click!
Mafkmm10_v2_chr5_+_139791513_1397915390.611.8e-04Click!
Nfe2mm10_v2_chr15_-_103251465_103251705-0.494.2e-03Click!


Activity profile for motif Nfe2_Bach1_Mafk.

activity profile for motif Nfe2_Bach1_Mafk


Sorted Z-values histogram for motif Nfe2_Bach1_Mafk

Sorted Z-values for motif Nfe2_Bach1_Mafk



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2_Bach1_Mafk

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5725639 6.800 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr1_-_33907721 4.672 ENSMUST00000115161.1
ENSMUST00000062289.8
 Bend6

BEN domain containing 6

chr2_+_136713444 3.123 ENSMUST00000028727.4
ENSMUST00000110098.3
 Snap25

synaptosomal-associated protein 25

chr2_+_155775333 2.605 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr3_-_116968827 2.298 ENSMUST00000119557.1
 Palmd
palmdelphin
chr1_+_136131382 2.183 ENSMUST00000075164.4
 Kif21b
kinesin family member 21B
chr13_-_54611274 2.025 ENSMUST00000049575.7
 Cltb
clathrin, light polypeptide (Lcb)
chr7_+_127244511 1.855 ENSMUST00000052509.4
 Zfp771
zinc finger protein 771
chr13_-_54611332 1.801 ENSMUST00000091609.4
 Cltb
clathrin, light polypeptide (Lcb)
chr1_+_33908172 1.687 ENSMUST00000182513.1
ENSMUST00000183034.1
 Dst

dystonin

chr6_+_5725812 1.640 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chrX_-_103186618 1.552 ENSMUST00000121720.1
 Nap1l2
nucleosome assembly protein 1-like 2
chr17_-_56133817 1.477 ENSMUST00000167545.1
 Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr3_+_123267445 1.477 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr18_-_43059418 1.459 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr16_+_20694908 1.458 ENSMUST00000056518.6
 Fam131a
family with sequence similarity 131, member A
chr6_+_124996681 1.454 ENSMUST00000032479.4
 Pianp
PILR alpha associated neural protein
chr19_-_8839181 1.314 ENSMUST00000096259.4
 Gng3
guanine nucleotide binding protein (G protein), gamma 3
chr5_-_139484420 1.302 ENSMUST00000150992.1
 Zfand2a
zinc finger, AN1-type domain 2A
chr3_+_146852359 1.236 ENSMUST00000038090.5
ENSMUST00000170055.1
 Ttll7

tubulin tyrosine ligase-like family, member 7


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.3 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.1 4.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 3.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.2 3.1 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.2 2.8 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.3 2.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 2.2 GO:0007018 microtubule-based movement(GO:0007018)
0.2 2.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 1.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.2 1.5 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.0 1.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.4 1.4 GO:0035617 stress granule disassembly(GO:0035617)
0.2 1.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 1.4 GO:0031103 axon regeneration(GO:0031103)
0.0 1.4 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.2 GO:0036465 synaptic vesicle recycling(GO:0036465)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 3.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 3.2 GO:0071565 nBAF complex(GO:0071565)
0.0 3.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.8 3.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 2.7 GO:0043197 dendritic spine(GO:0043197)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.6 GO:0005604 basement membrane(GO:0005604)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.4 1.7 GO:0031673 H zone(GO:0031673)
0.1 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.4 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.4 1.1 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.2 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.1 GO:0032279 asymmetric synapse(GO:0032279)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 8.4 GO:0045503 dynein light chain binding(GO:0045503)
0.1 4.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 3.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 3.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 3.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.6 GO:0045296 cadherin binding(GO:0045296)
0.0 2.4 GO:0008017 microtubule binding(GO:0008017)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.5 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.5 GO:0017022 myosin binding(GO:0017022)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 1.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.1 GO:0032795 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)