Motif ID: Nfe2l1_Mafg

Z-value: 1.293

Transcription factors associated with Nfe2l1_Mafg:

Gene SymbolEntrez IDGene Name
Mafg ENSMUSG00000051510.7 Mafg
Mafg ENSMUSG00000053906.4 Mafg
Nfe2l1 ENSMUSG00000038615.11 Nfe2l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafgmm10_v2_chr11_-_120633594_120633605-0.796.2e-08Click!
Nfe2l1mm10_v2_chr11_-_96829483_968295020.134.7e-01Click!


Activity profile for motif Nfe2l1_Mafg.

activity profile for motif Nfe2l1_Mafg


Sorted Z-values histogram for motif Nfe2l1_Mafg

Sorted Z-values for motif Nfe2l1_Mafg



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 36.840 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chrX_-_141874870 7.819 ENSMUST00000182079.1
 Gm15294
predicted gene 15294
chr7_-_137314394 7.467 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr12_-_10900296 7.177 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr17_+_78491549 6.803 ENSMUST00000079363.4
 Gm10093
predicted pseudogene 10093
chr1_-_65051119 6.707 ENSMUST00000161960.1
ENSMUST00000087359.5
 Cryge

crystallin, gamma E

chr4_-_63662910 6.683 ENSMUST00000184252.1
 Gm11214
predicted gene 11214
chr12_-_56535047 6.398 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr11_-_33276334 6.303 ENSMUST00000183831.1
 Gm12117
predicted gene 12117
chr14_-_76237353 6.263 ENSMUST00000095471.4
 Rps2-ps6
ribosomal protein S2, pseudogene 6
chr9_-_79977782 6.140 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr2_+_130277157 5.378 ENSMUST00000028890.8
ENSMUST00000159373.1
 Nop56

NOP56 ribonucleoprotein

chrX_+_71663665 5.246 ENSMUST00000070449.5
 Gpr50
G-protein-coupled receptor 50
chr3_+_85915722 5.168 ENSMUST00000054148.7
 Gm9790
predicted gene 9790
chr1_-_45890078 4.967 ENSMUST00000183590.1
 Gm5269
predicted gene 5269
chr1_-_191183244 4.810 ENSMUST00000027941.8
 Atf3
activating transcription factor 3
chr12_-_54986363 4.723 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr10_+_52022502 4.532 ENSMUST00000163017.1
ENSMUST00000058347.4
 Vgll2

vestigial like 2 homolog (Drosophila)

chr6_-_99044414 4.484 ENSMUST00000177507.1
ENSMUST00000123992.1
 Foxp1

forkhead box P1

chr5_+_128601106 4.115 ENSMUST00000117102.2
 Fzd10
frizzled homolog 10 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.1 36.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.1 6.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 5.7 GO:0000077 DNA damage checkpoint(GO:0000077)
0.2 5.4 GO:0000154 rRNA modification(GO:0000154)
0.0 5.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 4.9 GO:0002088 lens development in camera-type eye(GO:0002088)
1.2 4.8 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.7 4.8 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 4.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.6 4.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.5 4.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 4.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 4.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 3.6 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.2 3.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.8 3.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 3.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 3.2 GO:2001222 regulation of neuron migration(GO:2001222)
0.5 3.0 GO:0060242 contact inhibition(GO:0060242)
0.9 2.8 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.9 GO:0005667 transcription factor complex(GO:0005667)
0.7 5.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.9 4.7 GO:0008623 CHRAC(GO:0008623)
0.1 4.2 GO:1990391 DNA repair complex(GO:1990391)
0.1 4.1 GO:0005581 collagen trimer(GO:0005581)
0.0 3.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.3 3.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 2.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 2.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 2.5 GO:0005811 lipid particle(GO:0005811)
0.3 2.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 2.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5 2.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 2.2 GO:0016460 myosin II complex(GO:0016460)
0.7 2.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.3 2.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 1.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.9 GO:0000502 proteasome complex(GO:0000502)
0.3 1.7 GO:0071817 MMXD complex(GO:0071817)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 41.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.7 6.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 6.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 5.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.4 5.4 GO:1990226 histone methyltransferase binding(GO:1990226)
1.7 5.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 4.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 4.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.2 4.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 4.2 GO:0015197 peptide transporter activity(GO:0015197)
0.1 4.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 4.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.6 3.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 3.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.6 3.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 2.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.9 GO:0019843 rRNA binding(GO:0019843)
0.0 2.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 2.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)