Motif ID: Nfia

Z-value: 2.638


Transcription factors associated with Nfia:

Gene SymbolEntrez IDGene Name
Nfia ENSMUSG00000028565.12 Nfia

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfiamm10_v2_chr4_+_97777606_977776320.639.0e-05Click!


Activity profile for motif Nfia.

activity profile for motif Nfia


Sorted Z-values histogram for motif Nfia

Sorted Z-values for motif Nfia



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfia

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_78324200 24.063 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr6_+_141524379 23.976 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr7_+_130936172 20.955 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr18_+_20665250 19.399 ENSMUST00000075312.3
Ttr
transthyretin
chr11_-_102897146 19.298 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr11_-_102897123 18.992 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr7_-_97417730 16.674 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr6_-_115251839 15.169 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr4_-_64046925 14.810 ENSMUST00000107377.3
Tnc
tenascin C
chr19_+_5740885 12.631 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr19_-_5457397 12.524 ENSMUST00000179549.1
Ccdc85b
coiled-coil domain containing 85B
chr5_-_104114088 12.442 ENSMUST00000031249.3
Sparcl1
SPARC-like 1
chr16_+_91269759 11.871 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chrX_+_166344692 11.573 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr19_-_42202150 10.447 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr8_+_57455898 10.100 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr5_+_66968416 10.100 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr15_+_40655020 9.837 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr6_+_90465287 9.599 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chr2_-_25469742 9.464 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr11_+_3488275 8.974 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr2_-_25470031 8.826 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr8_-_105943382 8.366 ENSMUST00000038896.7
Lcat
lecithin cholesterol acyltransferase
chr3_-_90514250 8.289 ENSMUST00000107340.1
ENSMUST00000060738.8
S100a1

S100 calcium binding protein A1

chr6_-_53820764 8.214 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr2_-_170406501 8.185 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr12_+_85473883 8.176 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr1_+_51289106 8.093 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr1_+_185454803 7.905 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr1_-_162859684 7.825 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr6_+_17306335 7.583 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr10_+_57784859 7.492 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr4_+_130055010 7.411 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chr10_+_127725392 7.395 ENSMUST00000026466.3
Tac2
tachykinin 2
chr3_-_116129615 7.291 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr17_-_31637135 7.264 ENSMUST00000118504.1
ENSMUST00000078509.5
ENSMUST00000067801.6
Cbs


cystathionine beta-synthase


chr11_-_116110211 7.237 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr11_+_63128973 7.222 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr16_-_36784784 7.031 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr7_-_134225088 6.838 ENSMUST00000067680.4
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_-_172219715 6.811 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr1_+_169928648 6.801 ENSMUST00000094348.3
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr12_-_70347536 6.784 ENSMUST00000110520.2
ENSMUST00000110522.2
ENSMUST00000167755.1
Trim9


tripartite motif-containing 9


chr19_+_4594312 6.715 ENSMUST00000113825.2
Pcx
pyruvate carboxylase
chrX_+_100729917 6.613 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr17_-_49564262 6.606 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr9_+_56865104 6.495 ENSMUST00000035661.5
Cspg4
chondroitin sulfate proteoglycan 4
chr5_+_66968559 6.360 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr5_-_77115145 6.279 ENSMUST00000081964.5
Hopx
HOP homeobox
chr5_+_139423151 6.278 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr3_+_90537306 6.229 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr6_+_115134899 6.204 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr4_-_148287927 6.135 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr17_-_25570678 6.107 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr11_+_3330781 6.081 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr12_+_37880700 6.035 ENSMUST00000040500.7
Dgkb
diacylglycerol kinase, beta
chr17_-_31636631 6.032 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr14_+_65970610 6.028 ENSMUST00000127387.1
Clu
clusterin
chr3_+_90537242 6.001 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr17_+_32685655 5.929 ENSMUST00000008801.6
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr11_+_3330401 5.910 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr1_-_124045247 5.842 ENSMUST00000112603.2
Dpp10
dipeptidylpeptidase 10
chrX_-_142306170 5.604 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr2_-_127482499 5.461 ENSMUST00000088538.5
Kcnip3
Kv channel interacting protein 3, calsenilin
chr6_+_112273758 5.399 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr14_+_65970804 5.314 ENSMUST00000138191.1
Clu
clusterin
chr1_+_152399824 5.293 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr8_+_84723003 5.285 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr9_+_65101453 5.262 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
Igdcc4


immunoglobulin superfamily, DCC subclass, member 4


chr1_+_42229726 5.249 ENSMUST00000066196.1
Gm9915
predicted gene 9915
chr15_-_81697256 5.223 ENSMUST00000072910.5
Chadl
chondroadherin-like
chrX_+_100730178 5.201 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr17_+_8340399 5.186 ENSMUST00000069742.6
Prr18
proline rich region 18
chr1_+_169929929 5.155 ENSMUST00000175731.1
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr1_-_134234492 4.984 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr8_+_71568866 4.969 ENSMUST00000034267.4
Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
chr13_-_21753851 4.948 ENSMUST00000074752.2
Hist1h2ak
histone cluster 1, H2ak
chr3_+_89520152 4.916 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr4_+_128058962 4.901 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr1_-_124045523 4.831 ENSMUST00000112606.1
Dpp10
dipeptidylpeptidase 10
chr9_-_54661870 4.790 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr3_+_90603767 4.787 ENSMUST00000001046.5
ENSMUST00000107330.1
S100a4

S100 calcium binding protein A4

chr1_+_93235836 4.676 ENSMUST00000062202.7
Sned1
sushi, nidogen and EGF-like domains 1
chr1_+_146497614 4.629 ENSMUST00000132847.1
ENSMUST00000166814.1
Brinp3

bone morphogenetic protein/retinoic acid inducible neural specific 3

chr18_-_39490649 4.612 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr10_+_4611971 4.583 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr4_+_11704439 4.456 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr8_-_84978709 4.454 ENSMUST00000064922.5
Junb
Jun-B oncogene
chr5_+_66745835 4.396 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr5_+_118169712 4.395 ENSMUST00000054836.6
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr3_+_76075583 4.394 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr17_+_86963279 4.382 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr9_+_44107268 4.368 ENSMUST00000114821.2
ENSMUST00000114818.2
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr2_-_147186389 4.360 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr17_+_24470393 4.359 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr14_+_32028989 4.330 ENSMUST00000022460.4
Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr4_+_102570065 4.305 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_+_59516264 4.269 ENSMUST00000114243.1
Gm973
predicted gene 973
chr17_+_32685610 4.247 ENSMUST00000168171.1
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr16_+_41532851 4.241 ENSMUST00000078873.4
Lsamp
limbic system-associated membrane protein
chr1_+_134182404 4.230 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr12_+_84009481 4.190 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr8_+_65967157 4.171 ENSMUST00000072482.6
March1
membrane-associated ring finger (C3HC4) 1
chr10_+_58813359 4.110 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr9_+_44107286 4.054 ENSMUST00000152956.1
ENSMUST00000114815.1
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr6_-_55681257 4.052 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr4_+_130047840 4.041 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr11_+_3332426 4.028 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr7_+_46397648 4.027 ENSMUST00000160433.1
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr7_+_113207465 4.007 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr6_+_103510874 3.995 ENSMUST00000066905.6
Chl1
cell adhesion molecule with homology to L1CAM
chr11_-_98329641 3.981 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chrX_+_10485121 3.967 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr11_-_89302545 3.952 ENSMUST00000061728.3
Nog
noggin
chrX_-_57338598 3.938 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr15_-_78405824 3.937 ENSMUST00000058659.7
Tst
thiosulfate sulfurtransferase, mitochondrial
chr11_+_3983636 3.930 ENSMUST00000078757.1
Gal3st1
galactose-3-O-sulfotransferase 1
chr8_-_105484350 3.917 ENSMUST00000044286.5
Zdhhc1
zinc finger, DHHC domain containing 1
chr12_-_85374696 3.885 ENSMUST00000040766.7
Tmed10
transmembrane emp24-like trafficking protein 10 (yeast)
chr13_-_21833575 3.883 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr15_-_37458523 3.812 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr13_-_19619820 3.808 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chr3_+_94933041 3.799 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr17_+_8340710 3.778 ENSMUST00000163887.1
Prr18
proline rich region 18
chr6_+_53819975 3.752 ENSMUST00000104970.2
Gm16499
predicted gene 16499
chr17_+_80944611 3.721 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr4_-_155992604 3.689 ENSMUST00000052185.3
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr13_-_71963713 3.679 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr13_+_23574381 3.658 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr10_+_62071014 3.612 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr13_+_49504774 3.581 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr4_-_14621805 3.578 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr10_+_40349265 3.557 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr2_+_62664279 3.535 ENSMUST00000028257.2
Gca
grancalcin
chr12_-_80132802 3.517 ENSMUST00000180643.1
2310015A10Rik
RIKEN cDNA 2310015A10 gene
chr6_+_134920401 3.514 ENSMUST00000067327.4
ENSMUST00000003115.6
Cdkn1b

cyclin-dependent kinase inhibitor 1B

chr13_+_94173992 3.446 ENSMUST00000121618.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chrX_+_99975570 3.444 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr9_-_54661666 3.406 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr5_-_18360384 3.390 ENSMUST00000074694.5
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr17_+_86753900 3.389 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chr6_+_121636173 3.385 ENSMUST00000032203.7
A2m
alpha-2-macroglobulin
chr18_+_8694077 3.361 ENSMUST00000171469.1
Gm5819
predicted gene 5819
chr11_+_121702591 3.297 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr13_-_23622502 3.273 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr4_+_109978004 3.266 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr14_+_13454010 3.240 ENSMUST00000112656.2
Synpr
synaptoporin
chr11_-_109611417 3.180 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
Wipi1


WD repeat domain, phosphoinositide interacting 1


chr5_+_66968961 3.170 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr11_+_3983704 3.169 ENSMUST00000063004.7
Gal3st1
galactose-3-O-sulfotransferase 1
chr2_-_154408078 3.165 ENSMUST00000028991.6
ENSMUST00000109728.1
Snta1

syntrophin, acidic 1

chr1_-_82586781 3.160 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr1_-_52490736 3.146 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chr3_+_55242526 3.141 ENSMUST00000054237.7
ENSMUST00000167204.1
Dclk1

doublecortin-like kinase 1

chr4_-_82705735 3.128 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr13_-_56296551 3.124 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr9_+_44107226 3.105 ENSMUST00000114816.1
C1qtnf5
C1q and tumor necrosis factor related protein 5
chr5_-_35679416 3.091 ENSMUST00000114233.2
Htra3
HtrA serine peptidase 3
chrX_+_142227923 3.070 ENSMUST00000042329.5
Nxt2
nuclear transport factor 2-like export factor 2
chr3_+_156562141 3.043 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr5_-_120588613 3.028 ENSMUST00000046426.8
Tpcn1
two pore channel 1
chr3_-_110142996 3.008 ENSMUST00000156177.2
Ntng1
netrin G1
chr12_-_41485751 3.006 ENSMUST00000043884.4
Lrrn3
leucine rich repeat protein 3, neuronal
chr11_+_67586520 3.000 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr7_+_88278085 2.981 ENSMUST00000032779.5
ENSMUST00000128791.1
Ctsc

cathepsin C

chr7_-_78577771 2.977 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr8_+_95534078 2.943 ENSMUST00000041569.3
Ccdc113
coiled-coil domain containing 113
chr9_+_25252439 2.931 ENSMUST00000115272.2
ENSMUST00000165594.2
Sept7

septin 7

chr10_-_49788743 2.929 ENSMUST00000105483.1
ENSMUST00000105487.1
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chrX_+_142228177 2.899 ENSMUST00000112914.1
Nxt2
nuclear transport factor 2-like export factor 2
chr9_+_44334685 2.884 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr12_-_75735729 2.859 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr7_-_121035096 2.857 ENSMUST00000065740.2
Gm9905
predicted gene 9905
chrX_-_143393893 2.851 ENSMUST00000166406.2
Chrdl1
chordin-like 1
chr13_+_5861489 2.847 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr14_-_8309770 2.836 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chrX_-_143933204 2.817 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr7_+_122289297 2.812 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr7_+_44849216 2.801 ENSMUST00000054343.8
Akt1s1
AKT1 substrate 1 (proline-rich)
chr2_-_51972990 2.794 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr3_+_156561792 2.793 ENSMUST00000074015.4
Negr1
neuronal growth regulator 1
chrX_+_99042581 2.782 ENSMUST00000036606.7
Stard8
START domain containing 8
chr3_+_27984145 2.768 ENSMUST00000067757.4
Pld1
phospholipase D1
chr5_-_51553896 2.756 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr12_-_72408934 2.751 ENSMUST00000078505.7
Rtn1
reticulon 1
chr6_-_59024470 2.745 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr7_-_134232005 2.738 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr2_-_26092149 2.730 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr10_-_53750880 2.683 ENSMUST00000020003.7
Fam184a
family with sequence similarity 184, member A
chr7_+_44849581 2.659 ENSMUST00000150335.1
ENSMUST00000107882.1
Akt1s1

AKT1 substrate 1 (proline-rich)

chr4_-_135494615 2.655 ENSMUST00000102549.3
Nipal3
NIPA-like domain containing 3
chr7_+_73375494 2.654 ENSMUST00000094312.5
ENSMUST00000119206.1
Rgma

RGM domain family, member A

chr17_+_86963077 2.636 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr14_+_120275669 2.633 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr7_+_35555367 2.628 ENSMUST00000181932.1
B230322F03Rik
RIKEN cDNA B230322F03 gene
chr7_+_35119285 2.626 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr6_+_15720654 2.619 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr11_-_100939540 2.613 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr13_+_51846673 2.592 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr17_-_46144156 2.590 ENSMUST00000024762.2
Rsph9
radial spoke head 9 homolog (Chlamydomonas)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 38.3 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
4.9 14.8 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
4.4 13.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
4.3 21.4 GO:0070327 thyroid hormone transport(GO:0070327)
4.2 12.6 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
3.7 18.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
3.5 21.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
3.5 10.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
3.3 9.8 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
3.3 9.8 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
3.2 15.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
3.1 6.1 GO:0072197 ureter morphogenesis(GO:0072197)
2.4 24.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.4 7.2 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
2.4 7.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
2.3 6.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
2.2 9.0 GO:0019372 lipoxygenase pathway(GO:0019372)
2.2 6.7 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.0 10.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
2.0 20.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.9 11.3 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
1.9 13.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.8 7.0 GO:0042938 dipeptide transport(GO:0042938)
1.7 5.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
1.7 8.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
1.7 5.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.7 11.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.5 4.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.5 4.4 GO:0019401 alditol biosynthetic process(GO:0019401)
1.4 4.2 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.3 4.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.3 13.1 GO:0090527 actin filament reorganization(GO:0090527)
1.3 3.9 GO:0035928 rRNA import into mitochondrion(GO:0035928)
1.3 3.9 GO:0035964 COPI-coated vesicle budding(GO:0035964)
1.3 3.9 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
1.2 7.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.2 4.9 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
1.2 6.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
1.1 3.4 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.1 4.6 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
1.1 3.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.1 2.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
1.1 5.4 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
1.0 6.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
1.0 4.2 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
1.0 3.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
1.0 4.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
1.0 3.1 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
1.0 8.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
1.0 8.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.0 4.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.9 2.8 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.9 4.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.9 1.8 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.9 3.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.9 2.7 GO:0030210 heparin biosynthetic process(GO:0030210)
0.9 1.8 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.9 4.4 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.8 4.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.8 3.4 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.8 0.8 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.8 2.4 GO:1905154 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154)
0.8 6.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.8 4.7 GO:0019532 oxalate transport(GO:0019532)
0.8 2.4 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.8 3.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.8 6.8 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.7 2.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.7 9.6 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.7 1.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.7 8.0 GO:0016322 neuron remodeling(GO:0016322)
0.7 2.9 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.7 2.1 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.7 6.3 GO:0009404 toxin metabolic process(GO:0009404)
0.7 7.6 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.7 2.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603)
0.7 3.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.6 1.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.6 17.5 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.6 6.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.6 1.8 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) neuron death in response to hydrogen peroxide(GO:0036476) Fc-epsilon receptor signaling pathway(GO:0038095) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.6 2.3 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.6 2.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.6 6.7 GO:0035994 response to muscle stretch(GO:0035994)
0.5 2.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.5 1.1 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.5 1.6 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5 1.6 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.5 5.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.5 2.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.5 5.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.5 8.2 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.5 5.1 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.5 1.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.5 4.0 GO:0046415 urate metabolic process(GO:0046415)
0.5 1.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.5 2.0 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.5 1.5 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.5 7.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.5 2.4 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.5 1.8 GO:0097167 circadian regulation of translation(GO:0097167)
0.5 3.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.4 7.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.4 2.2 GO:0007386 compartment pattern specification(GO:0007386)
0.4 0.9 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.4 7.5 GO:0060134 prepulse inhibition(GO:0060134)
0.4 10.1 GO:0033622 integrin activation(GO:0033622)
0.4 1.8 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.4 2.2 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.4 2.2 GO:0045006 DNA deamination(GO:0045006)
0.4 0.4 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.4 1.3 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4 2.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 1.3 GO:0048352 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352)
0.4 2.1 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.4 1.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 6.5 GO:0015693 magnesium ion transport(GO:0015693)
0.4 7.2 GO:0032060 bleb assembly(GO:0032060)
0.4 2.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.4 0.8 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.4 1.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 1.1 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.4 2.6 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.4 2.6 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.4 2.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.4 1.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.4 1.8 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.3 2.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3 2.1 GO:0019695 choline metabolic process(GO:0019695)
0.3 0.7 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.3 1.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.3 3.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.3 3.2 GO:0043206 extracellular fibril organization(GO:0043206)
0.3 7.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.3 2.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.3 1.0 GO:0007525 somatic muscle development(GO:0007525)
0.3 4.1 GO:0021542 dentate gyrus development(GO:0021542)
0.3 0.9 GO:0006553 lysine metabolic process(GO:0006553)
0.3 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 1.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 0.6 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.3 2.1 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.3 1.8 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.3 10.2 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 1.1 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.3 5.6 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.3 1.4 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.3 0.6 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.3 1.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 1.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 1.6 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.3 2.1 GO:0030033 microvillus assembly(GO:0030033)
0.3 0.8 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.3 1.1 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.3 0.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 2.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 2.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 0.8 GO:2000668 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.3 2.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 0.8 GO:0097460 ferrous iron import into cell(GO:0097460)
0.2 0.5 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.2 0.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 4.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 4.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 6.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 5.3 GO:0048266 behavioral response to pain(GO:0048266)
0.2 0.7 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 2.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 0.7 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.2 9.1 GO:0070206 protein trimerization(GO:0070206)
0.2 2.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 1.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 1.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.9 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 0.9 GO:0035063 nuclear speck organization(GO:0035063)
0.2 0.4 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.2 0.9 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 9.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 0.6 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.2 0.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 2.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 0.8 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.2 3.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 2.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.2 2.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.2 7.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.2 2.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 2.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 0.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 1.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 2.6 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.2 2.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 1.9 GO:0071625 vocalization behavior(GO:0071625)
0.2 2.1 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 0.5 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.2 0.5 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 0.7 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.2 1.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.2 0.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 1.8 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 2.1 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.1 0.9 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 1.0 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.7 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 1.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 6.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 7.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 1.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 1.4 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.2 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 0.4 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.1 4.8 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 3.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 2.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.5 GO:1990743 protein sialylation(GO:1990743)
0.1 1.5 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1 18.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 0.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.4 GO:1903546 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.1 1.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.0 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.7 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 1.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.8 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.1 8.2 GO:0051592 response to calcium ion(GO:0051592)
0.1 1.8 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 2.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 2.2 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 4.5 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 3.6 GO:0035640 exploration behavior(GO:0035640)
0.1 1.4 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.1 1.0 GO:0006273 lagging strand elongation(GO:0006273)
0.1 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.4 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 7.5 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 1.0 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 1.9 GO:0014047 glutamate secretion(GO:0014047)
0.1 1.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.9 GO:0051642 centrosome localization(GO:0051642)
0.1 1.1 GO:0035094 response to nicotine(GO:0035094)
0.1 2.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 2.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 7.6 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.5 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 1.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 3.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.1 3.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 2.1 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 0.7 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.0 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.1 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.3 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.5 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.4 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 1.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.3 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 0.3 GO:0000022 mitotic spindle elongation(GO:0000022) spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:0060539 diaphragm development(GO:0060539)
0.1 2.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.4 GO:0007616 long-term memory(GO:0007616)
0.1 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.1 0.5 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.7 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 3.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.4 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0097421 liver regeneration(GO:0097421)
0.0 1.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.0 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.3 GO:0046051 UTP metabolic process(GO:0046051)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.9 GO:0010324 membrane invagination(GO:0010324)
0.0 3.5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 1.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 3.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.6 GO:0043153 photoperiodism(GO:0009648) entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 1.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.1 GO:0016050 vesicle organization(GO:0016050)
0.0 0.5 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0035150 regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.0 0.8 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.9 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.0 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 1.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 1.1 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.6 38.3 GO:0097450 astrocyte end-foot(GO:0097450)
2.5 10.1 GO:0044306 neuron projection terminus(GO:0044306)
2.3 6.8 GO:0014802 terminal cisterna(GO:0014802)
1.6 11.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
1.4 8.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.3 3.9 GO:0070765 gamma-secretase complex(GO:0070765)
1.1 17.8 GO:0005614 interstitial matrix(GO:0005614)
1.0 2.9 GO:0005940 septin ring(GO:0005940)
0.9 2.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.7 7.7 GO:0031931 TORC1 complex(GO:0031931)
0.7 6.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.7 7.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.7 2.0 GO:0071953 elastic fiber(GO:0071953)
0.6 3.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.6 6.3 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.6 3.1 GO:0044326 dendritic spine neck(GO:0044326)
0.6 3.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.6 9.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.5 1.6 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.5 2.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 11.2 GO:0031430 M band(GO:0031430)
0.5 8.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 1.6 GO:0044308 axonal spine(GO:0044308)
0.4 2.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.4 1.1 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.3 2.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 9.0 GO:0030673 axolemma(GO:0030673)
0.3 1.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 2.0 GO:0032589 neuron projection membrane(GO:0032589)
0.3 1.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 4.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 21.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 1.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 2.1 GO:0033391 chromatoid body(GO:0033391)
0.3 0.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 1.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.3 2.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 5.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 6.9 GO:0097440 apical dendrite(GO:0097440)
0.2 2.5 GO:0061700 GATOR2 complex(GO:0061700)
0.2 2.2 GO:1990909 Wnt signalosome(GO:1990909)
0.2 13.2 GO:0005581 collagen trimer(GO:0005581)
0.2 21.2 GO:0031225 anchored component of membrane(GO:0031225)
0.2 4.7 GO:0043218 compact myelin(GO:0043218)
0.2 16.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 5.2 GO:0002102 podosome(GO:0002102)
0.2 57.5 GO:0031012 extracellular matrix(GO:0031012)
0.2 15.1 GO:0000786 nucleosome(GO:0000786)
0.2 2.8 GO:0005922 connexon complex(GO:0005922)
0.2 3.2 GO:0000421 autophagosome membrane(GO:0000421)
0.2 1.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 2.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 2.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.6 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 2.8 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.0 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 4.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 10.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 6.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 12.9 GO:0005901 caveola(GO:0005901)
0.1 13.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 14.6 GO:0005884 actin filament(GO:0005884)
0.1 5.3 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 3.4 GO:0031526 brush border membrane(GO:0031526)
0.1 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.8 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.5 GO:0000145 exocyst(GO:0000145)
0.1 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 23.9 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.5 GO:0051286 cell tip(GO:0051286)
0.1 7.4 GO:0005814 centriole(GO:0005814)
0.1 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 4.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.5 GO:0070938 contractile ring(GO:0070938)
0.1 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 8.0 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 3.4 GO:0072562 blood microparticle(GO:0072562)
0.1 0.6 GO:0034464 BBSome(GO:0034464)
0.1 2.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 2.3 GO:0014704 intercalated disc(GO:0014704)
0.1 3.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 48.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0005902 microvillus(GO:0005902)
0.1 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.8 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 2.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 6.1 GO:0005911 cell-cell junction(GO:0005911)
0.0 7.0 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 3.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 10.2 GO:0030424 axon(GO:0030424)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 1.3 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 38.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.3 GO:0005770 late endosome(GO:0005770)
0.0 0.6 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 45.9 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.8 GO:0031514 motile cilium(GO:0031514)
0.0 3.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 24.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
5.3 16.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
4.6 18.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
4.4 13.3 GO:0098809 nitrite reductase activity(GO:0098809)
4.0 24.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.7 21.4 GO:0070324 thyroid hormone binding(GO:0070324)
2.5 14.8 GO:0045545 syndecan binding(GO:0045545)
2.1 8.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
2.0 10.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.8 7.3 GO:0008131 primary amine oxidase activity(GO:0008131)
1.8 10.9 GO:0030284 estrogen receptor activity(GO:0030284)
1.8 7.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.6 6.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.4 7.0 GO:0042895 antibiotic transporter activity(GO:0042895)
1.3 13.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.3 7.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.3 6.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.2 15.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
1.2 3.5 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
1.2 4.6 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
1.1 3.4 GO:0019966 C-X-C chemokine binding(GO:0019958) interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120)
1.1 6.7 GO:0009374 biotin binding(GO:0009374)
1.1 4.4 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
1.1 1.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
1.0 22.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.0 3.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
1.0 10.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.9 6.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.9 2.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.8 4.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.8 4.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.8 4.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.8 4.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.8 7.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.8 3.9 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.8 3.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.8 2.3 GO:0070052 collagen V binding(GO:0070052)
0.7 2.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.7 2.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.7 3.3 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062) fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.6 7.5 GO:0044548 S100 protein binding(GO:0044548)
0.6 2.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.6 12.5 GO:0051787 misfolded protein binding(GO:0051787)
0.6 8.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.6 2.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 6.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 7.0 GO:0005522 profilin binding(GO:0005522)
0.5 6.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.5 1.6 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.5 11.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.5 2.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.5 2.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 6.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.5 3.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.5 10.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 47.2 GO:0005178 integrin binding(GO:0005178)
0.4 1.8 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.4 1.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415) hyaluronan synthase activity(GO:0050501)
0.4 4.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.4 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.4 2.5 GO:0070728 leucine binding(GO:0070728)
0.4 2.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 2.2 GO:0043426 MRF binding(GO:0043426)
0.4 2.5 GO:0005523 tropomyosin binding(GO:0005523)
0.4 2.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.4 4.2 GO:0050897 cobalt ion binding(GO:0050897)
0.3 2.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 1.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.3 6.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 2.0 GO:0005042 netrin receptor activity(GO:0005042)
0.3 2.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 5.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 4.9 GO:0008430 selenium binding(GO:0008430)
0.3 2.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 1.3 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.3 1.3 GO:0042731 PH domain binding(GO:0042731)
0.3 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.3 2.5 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.3 1.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 1.8 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.3 1.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.3 1.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 1.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.3 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 1.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3 1.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 7.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 0.8 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.3 2.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.3 4.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 14.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.3 1.0 GO:0051425 PTB domain binding(GO:0051425)
0.3 14.9 GO:0005518 collagen binding(GO:0005518)
0.3 1.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.3 1.3 GO:0098821 BMP receptor activity(GO:0098821)
0.2 8.0 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.0 GO:2001069 glycogen binding(GO:2001069)
0.2 1.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 2.6 GO:0030957 Tat protein binding(GO:0030957)
0.2 2.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 5.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 4.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 0.9 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 0.9 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 0.6 GO:0004560 alpha-L-fucosidase activity(GO:0004560)
0.2 1.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 2.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.2 0.6 GO:0008527 taste receptor activity(GO:0008527)
0.2 1.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.2 3.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 5.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 0.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 0.6 GO:0005119 smoothened binding(GO:0005119)
0.2 3.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 3.5 GO:0042287 MHC protein binding(GO:0042287)
0.2 0.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 6.1 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 0.5 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.2 4.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 2.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 2.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 2.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 2.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 0.5 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.2 1.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 1.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0031896 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896)
0.1 3.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.0 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.9 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.1 1.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 11.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.1 3.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.7 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0070404 NADH binding(GO:0070404)
0.1 5.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 6.3 GO:0020037 heme binding(GO:0020037)
0.1 1.0 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 0.9 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772)
0.1 0.8 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 3.8 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 7.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.1 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 2.8 GO:0042805 actinin binding(GO:0042805)
0.1 3.1 GO:0008009 chemokine activity(GO:0008009)
0.1 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 3.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 3.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 4.9 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.9 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.0 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.1 4.9 GO:0019003 GDP binding(GO:0019003)
0.1 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 8.5 GO:0000149 SNARE binding(GO:0000149)
0.1 2.7 GO:0016414 O-octanoyltransferase activity(GO:0016414)
0.1 2.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 1.4 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 1.0 GO:0070402 NADPH binding(GO:0070402)
0.1 2.7 GO:0030332 cyclin binding(GO:0030332)
0.1 1.5 GO:0030371 translation repressor activity(GO:0030371)
0.1 2.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.9 GO:0019894 kinesin binding(GO:0019894)
0.1 1.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.3 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.1 0.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 15.6 GO:0003779 actin binding(GO:0003779)
0.0 1.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 4.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 2.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.0 GO:0016209 antioxidant activity(GO:0016209)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 4.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)