Motif ID: Nhlh1

Z-value: 1.472


Transcription factors associated with Nhlh1:

Gene SymbolEntrez IDGene Name
Nhlh1 ENSMUSG00000051251.3 Nhlh1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nhlh1mm10_v2_chr1_-_172057573_172057598-0.183.3e-01Click!


Activity profile for motif Nhlh1.

activity profile for motif Nhlh1


Sorted Z-values histogram for motif Nhlh1

Sorted Z-values for motif Nhlh1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nhlh1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 16.335 ENSMUST00000107377.3
 Tnc
tenascin C
chr16_+_91269759 13.490 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr4_-_120287349 11.483 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr7_+_130936172 8.986 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr10_-_27616895 8.141 ENSMUST00000092639.5
 Lama2
laminin, alpha 2
chr4_+_104367549 8.133 ENSMUST00000106830.2
 Dab1
disabled 1
chr3_-_84304762 8.010 ENSMUST00000107692.1
 Trim2
tripartite motif-containing 2
chr2_+_25395866 7.446 ENSMUST00000028328.2
 Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr10_+_3366125 6.711 ENSMUST00000043374.5
 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr19_-_5457397 6.390 ENSMUST00000179549.1
 Ccdc85b
coiled-coil domain containing 85B
chr15_+_81811414 6.149 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr2_+_70562007 6.011 ENSMUST00000094934.4
 Gad1
glutamate decarboxylase 1
chr13_-_32802849 5.928 ENSMUST00000057911.1
 D930007J09Rik
RIKEN cDNA D930007J09 gene
chr1_+_86045863 5.770 ENSMUST00000165824.1
 2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr6_-_39118211 5.626 ENSMUST00000038398.6
 Parp12
poly (ADP-ribose) polymerase family, member 12
chr11_+_113619318 5.595 ENSMUST00000146390.2
ENSMUST00000106630.1
 Sstr2

somatostatin receptor 2

chr7_+_46396439 5.577 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr15_+_81936753 5.552 ENSMUST00000038757.7
 Csdc2
cold shock domain containing C2, RNA binding
chr1_-_84696182 5.203 ENSMUST00000049126.6
 Dner
delta/notch-like EGF-related receptor
chr6_-_125494754 5.136 ENSMUST00000032492.8
 Cd9
CD9 antigen

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 431 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.9 15.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 13.8 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.4 12.0 GO:0060074 synapse maturation(GO:0060074)
0.2 12.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
1.5 10.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.4 9.7 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
1.5 9.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.7 8.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.4 8.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.9 7.6 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
2.4 7.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.6 6.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 6.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 6.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 5.8 GO:0006813 potassium ion transport(GO:0006813)
0.7 5.5 GO:0032570 response to progesterone(GO:0032570)
0.1 5.5 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 5.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.9 5.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
1.8 5.3 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 170 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 16.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 15.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.6 13.6 GO:0005605 basal lamina(GO:0005605)
0.1 13.3 GO:0005802 trans-Golgi network(GO:0005802)
0.4 12.6 GO:0060077 inhibitory synapse(GO:0060077)
0.4 12.1 GO:0030673 axolemma(GO:0030673)
0.2 11.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 9.7 GO:0005769 early endosome(GO:0005769)
0.5 9.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 7.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 7.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2 7.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 6.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 6.5 GO:0030427 site of polarized growth(GO:0030427)
0.1 6.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 5.8 GO:0031672 A band(GO:0031672)
0.4 5.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 5.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 5.3 GO:0001669 acrosomal vesicle(GO:0001669)
1.3 5.0 GO:0043511 inhibin complex(GO:0043511)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 277 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 21.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.3 16.5 GO:0017022 myosin binding(GO:0017022)
2.6 15.5 GO:0045545 syndecan binding(GO:0045545)
1.5 10.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 10.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.7 9.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.3 9.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 9.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 8.3 GO:0051015 actin filament binding(GO:0051015)
1.4 8.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.9 7.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.2 6.8 GO:0005112 Notch binding(GO:0005112)
1.6 6.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 6.1 GO:0017154 semaphorin receptor activity(GO:0017154)
1.0 5.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 5.8 GO:0030215 semaphorin receptor binding(GO:0030215)
1.9 5.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 5.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 5.3 GO:0019208 phosphatase regulator activity(GO:0019208)
0.3 5.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)