Motif ID: Nkx2-4
Z-value: 0.573
Transcription factors associated with Nkx2-4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nkx2-4 | ENSMUSG00000054160.2 | Nkx2-4 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nkx2-4 | mm10_v2_chr2_-_147085445_147085483 | -0.07 | 7.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 73 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.0 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 2.8 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.2 | 2.5 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.8 | 2.4 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.1 | 2.2 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.2 | 2.1 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.5 | 1.6 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.2 | 1.4 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
| 0.3 | 1.2 | GO:1903181 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) |
| 0.2 | 0.9 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
| 0.1 | 0.9 | GO:0021860 | pyramidal neuron development(GO:0021860) |
| 0.0 | 0.9 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 0.8 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
| 0.1 | 0.7 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 0.1 | 0.7 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.0 | 0.7 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.2 | 0.5 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
| 0.0 | 0.4 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
| 0.1 | 0.3 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.1 | 0.3 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
Gene overrepresentation in cellular_component category:
Showing 1 to 9 of 9 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 2.1 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
| 0.0 | 1.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.2 | 1.0 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 0.9 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 0.8 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.5 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 0.3 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.1 | 0.2 | GO:0044299 | C-fiber(GO:0044299) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 20 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 6.0 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.2 | 3.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.1 | 2.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 2.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 1.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 1.4 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.1 | 1.2 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 0.1 | 1.0 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.3 | 0.9 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.0 | 0.9 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.0 | 0.9 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 0.8 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.5 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.3 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.0 | 0.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 0.3 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.1 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
