Motif ID: Nkx3-1

Z-value: 0.632


Transcription factors associated with Nkx3-1:

Gene SymbolEntrez IDGene Name
Nkx3-1 ENSMUSG00000022061.8 Nkx3-1



Activity profile for motif Nkx3-1.

activity profile for motif Nkx3-1


Sorted Z-values histogram for motif Nkx3-1

Sorted Z-values for motif Nkx3-1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx3-1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_164269371 3.128 ENSMUST00000145412.1
ENSMUST00000033749.7
Pir

pirin

chr9_+_78191966 2.892 ENSMUST00000034903.5
Gsta4
glutathione S-transferase, alpha 4
chr4_-_140774196 2.819 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chr9_-_20976762 2.346 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr10_-_13324160 2.326 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr19_+_20601958 2.081 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr13_+_51408618 2.037 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr1_-_163289214 1.909 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chrX_+_150547375 1.904 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chrX_-_75875101 1.898 ENSMUST00000114059.3
Pls3
plastin 3 (T-isoform)
chrX_-_75874536 1.757 ENSMUST00000033547.7
Pls3
plastin 3 (T-isoform)
chr4_-_132757162 1.704 ENSMUST00000030709.8
Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
chr10_-_13324250 1.546 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr10_+_94514825 1.543 ENSMUST00000065060.5
Tmcc3
transmembrane and coiled coil domains 3
chr10_-_12861735 1.540 ENSMUST00000076817.4
Utrn
utrophin
chr8_+_114133557 1.516 ENSMUST00000073521.5
ENSMUST00000066514.6
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr17_+_56304313 1.475 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr9_-_124493793 1.462 ENSMUST00000178787.1
Gm21836
predicted gene, 21836
chr8_+_114133635 1.452 ENSMUST00000147605.1
ENSMUST00000134593.1
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr3_-_104818539 1.436 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr6_+_128362919 1.296 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr3_+_14863495 1.280 ENSMUST00000029076.4
Car3
carbonic anhydrase 3
chrX_+_100625737 1.225 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr1_-_175688353 1.168 ENSMUST00000104984.1
Chml
choroideremia-like
chr14_-_55788810 1.110 ENSMUST00000022830.6
ENSMUST00000168716.1
ENSMUST00000178399.1
Ripk3


receptor-interacting serine-threonine kinase 3


chr11_+_97685903 1.109 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chr17_+_37270214 1.053 ENSMUST00000038580.6
H2-M3
histocompatibility 2, M region locus 3
chr9_+_72438534 1.039 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr7_-_127930066 1.037 ENSMUST00000032988.8
Prss8
protease, serine, 8 (prostasin)
chr7_+_43607169 1.027 ENSMUST00000120935.1
ENSMUST00000127765.1
ENSMUST00000032661.7
Zfp819


zinc finger protein 819


chr5_-_8422582 1.001 ENSMUST00000168500.1
ENSMUST00000002368.9
Dbf4

DBF4 homolog (S. cerevisiae)

chr8_-_123318553 0.998 ENSMUST00000118395.1
ENSMUST00000035495.8
Fanca

Fanconi anemia, complementation group A

chr17_-_25727364 0.984 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr9_+_77921908 0.966 ENSMUST00000133757.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr9_+_72438519 0.926 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr13_-_99900645 0.917 ENSMUST00000022150.6
Cartpt
CART prepropeptide
chr18_+_60963517 0.908 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr15_-_50882806 0.894 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr5_-_149051300 0.877 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr18_+_82910863 0.850 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr11_-_21370452 0.833 ENSMUST00000102875.4
Ugp2
UDP-glucose pyrophosphorylase 2
chr2_+_3114220 0.828 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr3_-_57575907 0.810 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr14_-_54864055 0.809 ENSMUST00000142283.2
Homez
homeodomain leucine zipper-encoding gene
chr4_-_156255327 0.795 ENSMUST00000179919.1
Samd11
sterile alpha motif domain containing 11
chrX_+_56454871 0.792 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr12_+_52516077 0.779 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr7_+_58658181 0.773 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr1_+_167598450 0.771 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr11_-_3976778 0.766 ENSMUST00000042344.1
4930556J24Rik
RIKEN cDNA 4930556J24 gene
chr15_+_78597047 0.760 ENSMUST00000043069.5
Cyth4
cytohesin 4
chr11_-_45955183 0.751 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr17_-_79715034 0.731 ENSMUST00000024894.1
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr2_+_71873224 0.723 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr7_+_75455534 0.720 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr4_+_3940747 0.718 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr10_+_4432467 0.717 ENSMUST00000095893.4
ENSMUST00000118544.1
ENSMUST00000117489.1
1700052N19Rik


RIKEN cDNA 1700052N19 gene


chr10_-_128211788 0.713 ENSMUST00000061995.8
Spryd4
SPRY domain containing 4
chr1_-_174921813 0.712 ENSMUST00000055294.3
Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr3_-_57575760 0.710 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chrX_+_140456613 0.700 ENSMUST00000033809.3
Prps1
phosphoribosyl pyrophosphate synthetase 1
chr11_+_97685794 0.694 ENSMUST00000107584.1
ENSMUST00000107585.2
Cisd3

CDGSH iron sulfur domain 3

chr19_-_61297069 0.691 ENSMUST00000179346.1
Gm21060
predicted gene, 21060
chr11_-_80080928 0.668 ENSMUST00000103233.3
ENSMUST00000061283.8
Crlf3

cytokine receptor-like factor 3

chr9_+_105053239 0.634 ENSMUST00000035177.8
ENSMUST00000149243.1
Mrpl3

mitochondrial ribosomal protein L3

chr15_-_75048837 0.607 ENSMUST00000179762.1
ENSMUST00000065408.9
Ly6c1

lymphocyte antigen 6 complex, locus C1

chr5_-_86676346 0.596 ENSMUST00000038448.6
Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr1_-_75046639 0.594 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chr1_+_167598384 0.591 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chrX_-_100625901 0.588 ENSMUST00000059099.6
Pdzd11
PDZ domain containing 11
chr17_-_47692466 0.584 ENSMUST00000113300.1
Prickle4
prickle homolog 4 (Drosophila)
chr7_+_100537192 0.572 ENSMUST00000120454.1
Coa4
cytochrome c oxidase assembly factor 4
chr2_+_163994960 0.572 ENSMUST00000018470.3
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr15_-_52478228 0.569 ENSMUST00000081993.1
Gm10020
predicted pseudogene 10020
chr9_+_40873981 0.563 ENSMUST00000067375.3
Bsx
brain specific homeobox
chr16_+_36934976 0.557 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr2_+_79707780 0.546 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
Ppp1r1c


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chrY_+_17874741 0.544 ENSMUST00000177639.1
Gm20831
predicted gene, 20831
chr2_+_110597298 0.541 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr11_-_17008647 0.532 ENSMUST00000102881.3
Plek
pleckstrin
chr7_+_100537052 0.520 ENSMUST00000054310.3
Coa4
cytochrome c oxidase assembly factor 4
chr4_+_116708571 0.495 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr18_-_12862624 0.479 ENSMUST00000121808.1
ENSMUST00000118313.1
Osbpl1a

oxysterol binding protein-like 1A

chr9_+_89199319 0.436 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr2_-_84775420 0.434 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84715160 0.432 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr5_+_136919137 0.430 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr8_-_23237623 0.420 ENSMUST00000033950.5
Gins4
GINS complex subunit 4 (Sld5 homolog)
chr1_-_53297001 0.419 ENSMUST00000126590.1
ENSMUST00000126412.1
ENSMUST00000135246.1
ENSMUST00000027267.7
Pms1



postmeiotic segregation increased 1 (S. cerevisiae)



chr5_+_138161071 0.411 ENSMUST00000019638.8
ENSMUST00000110951.1
Cops6

COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)

chr10_-_62486575 0.407 ENSMUST00000092473.3
Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr1_+_99772765 0.373 ENSMUST00000086738.3
Cntnap5b
contactin associated protein-like 5B
chr19_+_5406815 0.366 ENSMUST00000174412.1
ENSMUST00000153017.2
4930481A15Rik

RIKEN cDNA 4930481A15 gene

chr7_+_139214661 0.364 ENSMUST00000135509.1
Lrrc27
leucine rich repeat containing 27
chr17_-_65772686 0.347 ENSMUST00000070673.7
Rab31
RAB31, member RAS oncogene family
chr5_+_142629537 0.339 ENSMUST00000036872.9
ENSMUST00000110778.1
Wipi2

WD repeat domain, phosphoinositide interacting 2

chr15_-_75111684 0.336 ENSMUST00000100542.3
Ly6c2
lymphocyte antigen 6 complex, locus C2
chr14_+_79515618 0.335 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr1_+_161142706 0.318 ENSMUST00000111608.1
ENSMUST00000052245.8
Ankrd45

ankyrin repeat domain 45

chr18_-_42262053 0.315 ENSMUST00000097590.3
Lars
leucyl-tRNA synthetase
chr9_+_78051938 0.312 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr5_+_90367204 0.304 ENSMUST00000068250.3
Gm9958
predicted gene 9958
chr5_-_38491948 0.296 ENSMUST00000129099.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr12_+_17266545 0.295 ENSMUST00000057288.5
Pdia6
protein disulfide isomerase associated 6
chrX_-_111537947 0.291 ENSMUST00000132319.1
ENSMUST00000123951.1
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr2_-_84775388 0.290 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_155582656 0.263 ENSMUST00000126322.1
Gss
glutathione synthetase
chr6_-_108185552 0.261 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr7_-_126922887 0.247 ENSMUST00000134134.1
ENSMUST00000119781.1
ENSMUST00000121612.2
Tmem219


transmembrane protein 219


chr8_+_36457548 0.243 ENSMUST00000135373.1
ENSMUST00000147525.1
6430573F11Rik

RIKEN cDNA 6430573F11 gene

chr11_-_103697661 0.238 ENSMUST00000107013.2
Gosr2
golgi SNAP receptor complex member 2
chr5_+_28071356 0.238 ENSMUST00000059155.10
Insig1
insulin induced gene 1
chr6_+_88465409 0.237 ENSMUST00000032165.9
Ruvbl1
RuvB-like protein 1
chr5_-_21785115 0.233 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr17_-_78418083 0.221 ENSMUST00000070039.7
ENSMUST00000112487.1
Fez2

fasciculation and elongation protein zeta 2 (zygin II)

chr11_-_69920581 0.219 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr6_-_69284319 0.195 ENSMUST00000103349.1
Igkv4-69
immunoglobulin kappa variable 4-69
chr1_-_156034800 0.189 ENSMUST00000169241.1
Tor1aip1
torsin A interacting protein 1
chr7_-_28598140 0.185 ENSMUST00000108283.1
ENSMUST00000040531.8
Pak4
Samd4b
p21 protein (Cdc42/Rac)-activated kinase 4
sterile alpha motif domain containing 4B
chr5_+_107597760 0.180 ENSMUST00000112655.1
Rpap2
RNA polymerase II associated protein 2
chr5_-_72559599 0.167 ENSMUST00000074948.4
ENSMUST00000087216.5
Nfxl1

nuclear transcription factor, X-box binding-like 1

chr4_+_32623985 0.167 ENSMUST00000108178.1
Casp8ap2
caspase 8 associated protein 2
chr7_+_110627650 0.161 ENSMUST00000033054.8
Adm
adrenomedullin
chr16_+_20611585 0.157 ENSMUST00000115522.2
ENSMUST00000119224.1
ENSMUST00000079600.4
ENSMUST00000120394.1
Ece2



endothelin converting enzyme 2



chr1_-_162866502 0.149 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr2_+_132846638 0.148 ENSMUST00000028835.6
ENSMUST00000110122.3
Crls1

cardiolipin synthase 1

chr6_+_145953429 0.143 ENSMUST00000111701.1
Sspn
sarcospan
chr10_+_90576678 0.109 ENSMUST00000182284.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_-_104522615 0.089 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chrX_-_101222426 0.083 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr10_+_100488289 0.082 ENSMUST00000164751.1
Cep290
centrosomal protein 290
chr1_+_135133272 0.064 ENSMUST00000167080.1
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr5_+_21424934 0.059 ENSMUST00000056045.4
Fam185a
family with sequence similarity 185, member A
chr10_-_115185015 0.055 ENSMUST00000006949.8
Tph2
tryptophan hydroxylase 2
chr17_-_35162969 0.055 ENSMUST00000174805.1
Prrc2a
proline-rich coiled-coil 2A
chr1_-_133906973 0.053 ENSMUST00000126123.1
Optc
opticin
chr8_-_106011422 0.046 ENSMUST00000058579.5
Ddx28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr7_-_25237849 0.044 ENSMUST00000071739.5
ENSMUST00000108411.1
Gsk3a

glycogen synthase kinase 3 alpha

chr16_+_20535475 0.042 ENSMUST00000090023.6
ENSMUST00000007216.8
Ap2m1

adaptor-related protein complex 2, mu 1 subunit

chr11_-_106193511 0.037 ENSMUST00000007444.7
ENSMUST00000152008.1
ENSMUST00000103072.3
ENSMUST00000106867.1
Strada



STE20-related kinase adaptor alpha



chr10_-_14718191 0.037 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr10_+_90576252 0.033 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr12_-_100159601 0.028 ENSMUST00000021596.7
Nrde2
nrde-2 necessary for RNA interference, domain containing
chr9_-_103222063 0.027 ENSMUST00000170904.1
Trf
transferrin
chr4_+_62619515 0.016 ENSMUST00000084521.4
ENSMUST00000107424.1
Rgs3

regulator of G-protein signaling 3

chr9_-_43116514 0.013 ENSMUST00000061833.4
Tmem136
transmembrane protein 136
chr8_+_69791163 0.012 ENSMUST00000034326.6
Atp13a1
ATPase type 13A1
chr19_+_11469353 0.012 ENSMUST00000165310.1
Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chr1_+_161142661 0.005 ENSMUST00000125018.1
Ankrd45
ankyrin repeat domain 45
chr15_-_74997634 0.002 ENSMUST00000023248.6
Ly6a
lymphocyte antigen 6 complex, locus A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.8 2.3 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 2.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.5 1.5 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.1 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.3 2.8 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.3 0.9 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.3 0.9 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.3 0.8 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.3 1.1 GO:2000407 positive regulation of necrotic cell death(GO:0010940) regulation of T cell extravasation(GO:2000407)
0.3 2.0 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.2 0.7 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 1.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 0.7 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.2 1.5 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2 1.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.2 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 1.2 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.2 1.3 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 1.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.5 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 1.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 2.0 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 2.9 GO:0030224 monocyte differentiation(GO:0030224)
0.1 1.9 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.7 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 1.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 1.0 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.6 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.0 GO:0070633 transepithelial transport(GO:0070633)
0.1 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854) positive regulation of macrophage differentiation(GO:0045651)
0.1 0.9 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 1.4 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 1.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 1.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0010388 cullin deneddylation(GO:0010388)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.7 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.2 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.8 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750) response to cadmium ion(GO:0046686)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 3.4 GO:0060348 bone development(GO:0060348)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.3 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.6 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.8 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.0 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0097447 dendritic tree(GO:0097447)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 1.1 GO:0097342 ripoptosome(GO:0097342)
0.1 1.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.5 GO:0070938 contractile ring(GO:0070938)
0.1 0.4 GO:0005712 chiasma(GO:0005712)
0.1 3.7 GO:0032420 stereocilium(GO:0032420)
0.1 1.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.4 GO:0097422 tubular endosome(GO:0097422)
0.1 1.1 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.5 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.5 4.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.5 1.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 2.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 2.1 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 0.9 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.3 3.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 1.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.8 GO:0042731 PH domain binding(GO:0042731)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.7 GO:0070330 aromatase activity(GO:0070330)
0.1 1.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 2.2 GO:0016594 glycine binding(GO:0016594)
0.1 1.3 GO:0016151 nickel cation binding(GO:0016151)
0.1 2.9 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.7 GO:0036122 BMP binding(GO:0036122)
0.1 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.8 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 1.5 GO:0017166 vinculin binding(GO:0017166)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.0 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.8 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815)
0.1 1.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 1.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 2.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)