Motif ID: Nkx6-1_Evx1_Hesx1

Z-value: 0.680

Transcription factors associated with Nkx6-1_Evx1_Hesx1:

Gene SymbolEntrez IDGene Name
Evx1 ENSMUSG00000005503.8 Evx1
Hesx1 ENSMUSG00000040726.8 Hesx1
Nkx6-1 ENSMUSG00000035187.8 Nkx6-1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx6-1mm10_v2_chr5_-_101665195_101665226-0.134.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-1_Evx1_Hesx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_84417359 7.929 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr5_-_62766153 6.747 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_-_143933204 6.393 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chrX_-_143933089 5.501 ENSMUST00000087313.3
Dcx
doublecortin
chr11_-_98053415 5.355 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr15_+_18818895 5.241 ENSMUST00000166873.2
Cdh10
cadherin 10
chr16_-_97170707 4.821 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr2_-_79456750 4.690 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr9_-_55919605 4.416 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr7_+_126776939 4.351 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr7_+_126950518 4.108 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr1_+_72284367 4.000 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr1_-_155417394 3.895 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr2_+_116067213 3.661 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr15_-_8710409 3.513 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710734 3.501 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_113812547 3.496 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr7_+_126950687 3.400 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr17_+_3397189 3.349 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr5_+_19907502 3.265 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_37518341 3.033 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr7_+_29071597 2.939 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr12_-_24493656 2.913 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr8_-_109251698 2.906 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr13_+_23574381 2.781 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr3_+_62419668 2.758 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr7_+_35802593 2.702 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr16_+_45094036 2.690 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr2_-_116067391 2.615 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr11_-_87359011 2.434 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr9_-_53975246 2.390 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr3_-_80802789 2.281 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr1_-_155417283 2.273 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr17_+_3532554 2.254 ENSMUST00000168560.1
Cldn20
claudin 20
chr2_+_84734050 2.192 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr2_-_5676046 2.151 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr6_-_136171722 2.150 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr6_-_57535422 2.115 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr9_-_96719404 2.106 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr15_-_66812593 2.097 ENSMUST00000100572.3
Sla
src-like adaptor
chr5_+_19907774 2.093 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_158356258 2.011 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr6_-_101377897 2.006 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr13_+_42680565 2.000 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr2_-_7395879 1.919 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr3_+_55461758 1.918 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr11_+_75532099 1.889 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr3_+_32436376 1.851 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr17_-_31636631 1.809 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr11_+_16752203 1.794 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr3_+_76075583 1.792 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr4_-_155056784 1.788 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr18_+_23415400 1.748 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr2_+_23069210 1.734 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr16_-_42340595 1.728 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr16_+_42907563 1.721 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr16_-_45724600 1.718 ENSMUST00000096057.4
Tagln3
transgelin 3
chr2_-_45117349 1.716 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr13_-_41273977 1.708 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr16_-_74411292 1.702 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr5_+_66968416 1.694 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr6_-_126645784 1.691 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr1_-_132707304 1.673 ENSMUST00000043189.7
Nfasc
neurofascin
chr3_-_66296807 1.649 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr4_+_97777780 1.645 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr6_+_8948608 1.626 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr8_-_34965631 1.623 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr8_+_83666827 1.609 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr2_+_90885860 1.588 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr9_-_96719549 1.588 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr1_-_134955908 1.580 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr1_+_180109192 1.573 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr9_+_32116040 1.573 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chrM_+_10167 1.565 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr3_+_32436151 1.560 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr14_-_100149764 1.539 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr4_-_14621805 1.538 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr1_-_172027251 1.531 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chrX_+_163911401 1.494 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr7_+_126950837 1.491 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr9_+_118478182 1.481 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_-_112187766 1.455 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chrM_+_9870 1.448 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr5_-_131616599 1.430 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr15_+_92597104 1.421 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr13_+_83732438 1.419 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr2_+_125068118 1.409 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr18_+_69593361 1.407 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr13_+_21810428 1.404 ENSMUST00000091745.5
Hist1h2ao
histone cluster 1, H2ao
chr1_-_134955847 1.392 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr10_-_25200110 1.391 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr7_+_79273201 1.369 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chrX_+_159708593 1.364 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr5_+_13398688 1.348 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr17_+_25188380 1.346 ENSMUST00000039734.5
Unkl
unkempt-like (Drosophila)
chr2_-_144527341 1.331 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr9_+_118478344 1.319 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chrX_+_159697308 1.309 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr18_-_35215008 1.299 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr4_+_13743424 1.298 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_69897220 1.282 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr18_+_69344503 1.273 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr16_-_52296924 1.241 ENSMUST00000167115.1
Alcam
activated leukocyte cell adhesion molecule
chr15_+_21111452 1.231 ENSMUST00000075132.6
Cdh12
cadherin 12
chr9_-_15357692 1.170 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr16_-_16359016 1.164 ENSMUST00000023477.7
ENSMUST00000096229.3
ENSMUST00000115749.1
Dnm1l


dynamin 1-like


chr8_-_54724317 1.159 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr5_-_99252839 1.147 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr11_-_26210553 1.123 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr10_+_39612934 1.100 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr7_+_123123870 1.099 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chrX_+_101640056 1.091 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr5_-_124095749 1.086 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr1_-_24612700 1.084 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr6_-_56923927 1.076 ENSMUST00000031793.5
Nt5c3
5'-nucleotidase, cytosolic III
chr19_-_4698668 1.075 ENSMUST00000177696.1
Gm960
predicted gene 960
chr18_-_39487096 1.074 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr4_-_109665249 1.069 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr11_+_116843278 1.068 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr15_+_55307743 1.065 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr8_+_54954728 1.064 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr2_-_45112890 1.062 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr7_+_128688480 1.058 ENSMUST00000118605.1
Inpp5f
inositol polyphosphate-5-phosphatase F
chr2_-_153225396 1.057 ENSMUST00000099194.2
Tspyl3
TSPY-like 3
chr8_-_54724474 1.055 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr1_+_194619815 1.051 ENSMUST00000027952.5
Plxna2
plexin A2
chr2_-_52558539 1.045 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr5_+_66968559 1.043 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr8_-_36249292 1.036 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr4_+_108719649 1.035 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr2_-_173276144 1.029 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr2_+_69897255 1.029 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr8_-_26119125 1.024 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chr8_+_94152607 1.010 ENSMUST00000034211.8
Mt3
metallothionein 3
chrX_+_112604274 1.007 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr6_-_97459279 1.004 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr12_-_83487708 1.001 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr8_-_31918203 1.001 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr6_+_137252297 1.000 ENSMUST00000077115.6
ENSMUST00000167679.1
Ptpro

protein tyrosine phosphatase, receptor type, O

chr17_-_49564262 0.999 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr14_-_36935560 0.998 ENSMUST00000183038.1
Ccser2
coiled-coil serine rich 2
chr13_-_85127514 0.997 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr2_+_20737306 0.994 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr7_+_103550368 0.992 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr9_+_88581036 0.988 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chr8_+_40354303 0.982 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr3_-_123672321 0.970 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr18_+_57468478 0.969 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr13_+_94083490 0.967 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr2_+_68104671 0.966 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_-_45110336 0.962 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr7_-_73541738 0.950 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr12_+_38780284 0.909 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr3_-_146770603 0.906 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr16_+_38089001 0.905 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr3_+_68572245 0.903 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr12_+_38780817 0.891 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr3_+_68869563 0.891 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr14_-_88471396 0.885 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr9_-_48911067 0.876 ENSMUST00000003826.7
Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr17_-_29007925 0.872 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr10_+_73821857 0.870 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr8_+_66386292 0.858 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr10_+_18469958 0.850 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr16_-_52452465 0.850 ENSMUST00000170035.1
ENSMUST00000164728.1
Alcam

activated leukocyte cell adhesion molecule

chr13_+_42866247 0.833 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr11_+_75532127 0.832 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr12_+_16653470 0.818 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr9_-_96631487 0.818 ENSMUST00000128346.1
ENSMUST00000034984.6
Rasa2

RAS p21 protein activator 2

chr7_-_19699008 0.813 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr3_+_66219909 0.805 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr2_+_96318014 0.805 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chrX_-_134111852 0.799 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr2_+_4017727 0.796 ENSMUST00000177457.1
Frmd4a
FERM domain containing 4A
chr11_+_75531690 0.785 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr8_+_107031218 0.781 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chrX_-_75416533 0.772 ENSMUST00000033542.4
Mtcp1
mature T cell proliferation 1
chr16_+_43247278 0.770 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr5_+_88583527 0.767 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr7_-_81493883 0.765 ENSMUST00000082090.7
Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chrX_-_104857228 0.764 ENSMUST00000033575.5
Magee2
melanoma antigen, family E, 2
chr4_-_45532470 0.761 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr12_-_75735729 0.759 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr3_+_94398517 0.759 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chr11_+_103133333 0.755 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr7_-_73537621 0.753 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr19_+_44992127 0.750 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_+_178529113 0.743 ENSMUST00000161017.1
Kif26b
kinesin family member 26B
chr11_+_103133303 0.743 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr12_+_52699297 0.740 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr9_+_72274966 0.732 ENSMUST00000183410.1
Zfp280d
zinc finger protein 280D
chr12_-_91849081 0.732 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr16_-_63864114 0.728 ENSMUST00000064405.6
Epha3
Eph receptor A3
chrX_+_153237466 0.728 ENSMUST00000143880.1
Klf8
Kruppel-like factor 8
chrX_-_60403947 0.722 ENSMUST00000033480.6
ENSMUST00000101527.2
Atp11c

ATPase, class VI, type 11C

chr5_+_107497718 0.720 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr7_-_81493725 0.718 ENSMUST00000119121.1
Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr1_-_79440039 0.688 ENSMUST00000049972.4
Scg2
secretogranin II
chr14_-_103843685 0.688 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr17_-_90088343 0.684 ENSMUST00000173917.1
Nrxn1
neurexin I

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.6 4.8 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
1.2 4.7 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.1 3.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
1.0 6.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.9 2.8 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.9 4.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.9 8.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.8 6.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.7 11.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.6 3.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.6 3.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.6 2.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.6 1.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.6 1.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 1.7 GO:0050975 sensory perception of touch(GO:0050975)
0.5 1.6 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.5 1.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5 1.8 GO:0072592 oxygen metabolic process(GO:0072592)
0.5 0.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.4 1.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.4 1.7 GO:0016198 axon choice point recognition(GO:0016198)
0.4 1.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.4 1.2 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.6 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.4 8.7 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.4 1.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 1.8 GO:0051593 response to folic acid(GO:0051593)
0.4 2.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.4 1.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 1.7 GO:0030242 pexophagy(GO:0030242)
0.3 1.0 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 2.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 0.9 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.3 1.9 GO:0019532 oxalate transport(GO:0019532)
0.3 0.8 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.3 1.3 GO:0021856 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.3 0.8 GO:0019085 early viral transcription(GO:0019085)
0.3 0.8 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 2.7 GO:0042118 endothelial cell activation(GO:0042118)
0.3 2.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 0.8 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 1.0 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 1.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 0.7 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 1.2 GO:0090148 membrane fission(GO:0090148)
0.2 1.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 1.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.2 4.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2 1.0 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.2 0.6 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.2 0.8 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 0.7 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.2 0.5 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.2 0.7 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 1.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.3 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.2 1.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1 0.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.8 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.4 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 2.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.6 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.6 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 1.4 GO:0032570 response to progesterone(GO:0032570)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 1.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.5 GO:0033762 response to glucagon(GO:0033762)
0.1 0.5 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 2.2 GO:0007097 nuclear migration(GO:0007097)
0.1 0.4 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.5 GO:0030091 protein repair(GO:0030091)
0.1 0.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)
0.1 0.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.0 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 1.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.1 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.1 2.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.8 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.5 GO:0007351 blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 1.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.9 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 0.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169) regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.7 GO:0060074 synapse maturation(GO:0060074)
0.1 3.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.1 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.3 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 2.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.9 GO:0001553 luteinization(GO:0001553)
0.1 0.6 GO:0007379 segment specification(GO:0007379)
0.1 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 2.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 1.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 1.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.4 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 2.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.4 GO:0030035 microspike assembly(GO:0030035)
0.0 1.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 3.7 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 1.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.7 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 1.5 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 1.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 2.3 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.3 GO:0022410 circadian sleep/wake cycle process(GO:0022410) regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) circadian sleep/wake cycle, sleep(GO:0050802)
0.0 4.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 4.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 2.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 2.5 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 2.3 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0061153 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.0 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.5 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.4 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.1 3.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.1 5.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.6 1.8 GO:0031983 vesicle lumen(GO:0031983)
0.4 1.7 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 7.0 GO:0043205 fibril(GO:0043205)
0.4 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 1.2 GO:0060187 cell pole(GO:0060187)
0.3 0.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.6 GO:0071437 invadopodium(GO:0071437)
0.2 2.0 GO:0070688 MLL5-L complex(GO:0070688)
0.2 1.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 2.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.0 GO:0070695 FHF complex(GO:0070695)
0.1 1.6 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 2.3 GO:0032279 asymmetric synapse(GO:0032279)
0.1 2.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.8 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.8 GO:0090543 Flemming body(GO:0090543)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 7.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 3.3 GO:0031672 A band(GO:0031672)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.7 GO:0030673 axolemma(GO:0030673)
0.1 1.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.3 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.9 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.6 GO:0071565 nBAF complex(GO:0071565)
0.1 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.3 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.8 GO:0070822 Sin3-type complex(GO:0070822)
0.0 2.4 GO:0072562 blood microparticle(GO:0072562)
0.0 2.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 3.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 2.2 GO:0042641 actomyosin(GO:0042641)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 2.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 10.1 GO:0030425 dendrite(GO:0030425)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 1.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 3.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 6.6 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 3.6 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 4.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.4 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.1 8.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.9 5.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.8 6.2 GO:0001618 virus receptor activity(GO:0001618)
0.7 2.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 1.8 GO:0098809 nitrite reductase activity(GO:0098809)
0.6 1.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 11.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.4 3.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.4 1.6 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.4 2.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 1.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 1.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 1.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 1.7 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 0.8 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 1.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 0.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 1.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 3.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.2 1.1 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 2.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 1.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 1.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 2.0 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 1.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 2.8 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.8 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 7.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 4.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.7 GO:0070330 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) aromatase activity(GO:0070330)
0.1 7.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1 2.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 2.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.3 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 2.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.3 GO:0043422 protein kinase B binding(GO:0043422)
0.1 2.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0035925 translation repressor activity, nucleic acid binding(GO:0000900) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 9.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.9 GO:0030276 clathrin binding(GO:0030276)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 5.4 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.3 GO:0005234 ionotropic glutamate receptor activity(GO:0004970) extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 2.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.0 GO:0042393 histone binding(GO:0042393)