Motif ID: Nkx6-2

Z-value: 0.698


Transcription factors associated with Nkx6-2:

Gene SymbolEntrez IDGene Name
Nkx6-2 ENSMUSG00000041309.11 Nkx6-2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx6-2mm10_v2_chr7_-_139582790_139582808-0.449.5e-03Click!


Activity profile for motif Nkx6-2.

activity profile for motif Nkx6-2


Sorted Z-values histogram for motif Nkx6-2

Sorted Z-values for motif Nkx6-2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_96467606 3.963 ENSMUST00000061739.8
 Pcp4
Purkinje cell protein 4
chr18_-_42899294 3.803 ENSMUST00000117687.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr3_+_55461758 3.765 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr17_-_29888570 3.743 ENSMUST00000171691.1
 Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr1_+_194619815 3.410 ENSMUST00000027952.5
 Plxna2
plexin A2
chr5_-_131308076 3.242 ENSMUST00000160609.1
 Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr5_-_131307848 3.019 ENSMUST00000086023.5
 Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr1_+_66321708 2.843 ENSMUST00000114013.1
 Map2
microtubule-associated protein 2
chr2_+_22622183 2.648 ENSMUST00000028123.3
 Gad2
glutamic acid decarboxylase 2
chr1_-_126830632 2.596 ENSMUST00000112583.1
ENSMUST00000094609.3
 Nckap5

NCK-associated protein 5

chr2_+_62664279 2.537 ENSMUST00000028257.2
 Gca
grancalcin
chr1_+_66322102 2.185 ENSMUST00000123647.1
 Map2
microtubule-associated protein 2
chr10_+_106470281 2.129 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr15_+_99006056 1.988 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr3_+_103575275 1.856 ENSMUST00000090697.4
 Syt6
synaptotagmin VI
chr4_-_91376433 1.810 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
 Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr4_+_48049080 1.789 ENSMUST00000153369.1
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr4_-_97584612 1.734 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr5_+_19907502 1.668 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_+_18818895 1.645 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr8_+_93810832 1.533 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O

chr3_-_96220880 1.487 ENSMUST00000090782.3
 Hist2h2ac
histone cluster 2, H2ac
chr12_-_80760541 1.477 ENSMUST00000073251.6
 Ccdc177
coiled-coil domain containing 177
chr1_-_64121456 1.439 ENSMUST00000142009.1
ENSMUST00000114086.1
 Klf7

Kruppel-like factor 7 (ubiquitous)

chr5_+_19907774 1.434 ENSMUST00000115267.2
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_101171302 1.405 ENSMUST00000164474.1
ENSMUST00000043397.7
 Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr4_-_97584605 1.385 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_-_115276973 1.340 ENSMUST00000021078.2
 Fdxr
ferredoxin reductase
chr6_+_125049903 1.293 ENSMUST00000112413.1
 Acrbp
proacrosin binding protein
chr2_-_45117349 1.225 ENSMUST00000176438.2
 Zeb2
zinc finger E-box binding homeobox 2
chr4_+_127172866 1.202 ENSMUST00000106094.2
 Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr6_+_125049952 1.195 ENSMUST00000088294.5
ENSMUST00000032481.7
 Acrbp

proacrosin binding protein

chr5_-_20951769 1.180 ENSMUST00000036489.5
 Rsbn1l
round spermatid basic protein 1-like
chr1_+_15712303 1.174 ENSMUST00000170146.1
 Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr6_-_124769548 1.152 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
 Eno2


enolase 2, gamma neuronal


chr3_+_96601084 1.137 ENSMUST00000062058.3
 Lix1l
Lix1-like
chr3_+_103575231 1.103 ENSMUST00000121834.1
 Syt6
synaptotagmin VI
chrX_-_59567348 1.078 ENSMUST00000124402.1
 Fgf13
fibroblast growth factor 13
chr19_-_44107447 1.055 ENSMUST00000119591.1
ENSMUST00000026217.4
 Chuk

conserved helix-loop-helix ubiquitous kinase

chr11_-_17953861 0.968 ENSMUST00000076661.6
 Etaa1
Ewing's tumor-associated antigen 1
chr6_-_13839916 0.931 ENSMUST00000060442.7
 Gpr85
G protein-coupled receptor 85
chr5_+_66676098 0.871 ENSMUST00000031131.9
 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr15_-_73061204 0.866 ENSMUST00000089770.3
ENSMUST00000170633.1
ENSMUST00000168191.1
 Trappc9


trafficking protein particle complex 9


chr2_+_83812567 0.865 ENSMUST00000051454.3
 Fam171b
family with sequence similarity 171, member B
chr6_-_144209558 0.860 ENSMUST00000111749.1
ENSMUST00000170367.2
 Sox5

SRY-box containing gene 5

chr3_+_10088173 0.854 ENSMUST00000061419.7
 Gm9833
predicted gene 9833
chr10_+_79910856 0.792 ENSMUST00000181321.1
 Gm26602
predicted gene, 26602
chr18_-_84086379 0.782 ENSMUST00000060303.8
 Tshz1
teashirt zinc finger family member 1
chr6_-_144209471 0.763 ENSMUST00000038815.7
 Sox5
SRY-box containing gene 5
chr18_+_34840575 0.739 ENSMUST00000043484.7
 Reep2
receptor accessory protein 2
chr2_-_69789568 0.736 ENSMUST00000094942.3
 Ccdc173
coiled-coil domain containing 173
chr18_+_37355271 0.731 ENSMUST00000051163.1
 Pcdhb8
protocadherin beta 8
chr4_+_98546710 0.718 ENSMUST00000102792.3
 Inadl
InaD-like (Drosophila)
chr10_+_18407658 0.684 ENSMUST00000037341.7
 Nhsl1
NHS-like 1
chrX_-_59568068 0.650 ENSMUST00000119833.1
ENSMUST00000131319.1
 Fgf13

fibroblast growth factor 13

chr13_+_109926832 0.649 ENSMUST00000117420.1
 Pde4d
phosphodiesterase 4D, cAMP specific
chr1_-_126830786 0.638 ENSMUST00000162646.1
 Nckap5
NCK-associated protein 5
chr5_+_123142187 0.633 ENSMUST00000174836.1
ENSMUST00000163030.2
 Setd1b

SET domain containing 1B

chr2_-_37647199 0.622 ENSMUST00000028279.3
 Strbp
spermatid perinuclear RNA binding protein
chr6_-_144209448 0.594 ENSMUST00000077160.5
 Sox5
SRY-box containing gene 5
chr1_+_184034381 0.585 ENSMUST00000048655.7
 Dusp10
dual specificity phosphatase 10
chr1_-_64121389 0.571 ENSMUST00000055001.3
 Klf7
Kruppel-like factor 7 (ubiquitous)
chr4_+_90218820 0.554 ENSMUST00000107129.1
 Zfp352
zinc finger protein 352
chr5_-_51553896 0.553 ENSMUST00000132734.1
 Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr1_+_34005872 0.501 ENSMUST00000182296.1
 Dst
dystonin
chr4_+_98546919 0.500 ENSMUST00000030290.7
 Inadl
InaD-like (Drosophila)
chr7_+_39588931 0.493 ENSMUST00000178791.1
ENSMUST00000098511.3
 Gm2058

predicted gene 2058

chr18_+_37435602 0.491 ENSMUST00000055495.5
 Pcdhb12
protocadherin beta 12
chr18_+_37421418 0.490 ENSMUST00000053073.4
 Pcdhb11
protocadherin beta 11
chr2_+_157367594 0.489 ENSMUST00000081202.5
 Manbal
mannosidase, beta A, lysosomal-like
chr3_+_19894855 0.487 ENSMUST00000059704.4
 4632415L05Rik
RIKEN cDNA 4632415L05 gene
chr2_+_69861562 0.483 ENSMUST00000090852.4
ENSMUST00000166411.1
 Ssb

Sjogren syndrome antigen B

chrM_+_10167 0.448 ENSMUST00000082414.1
 mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr15_+_35371498 0.448 ENSMUST00000048646.7
 Vps13b
vacuolar protein sorting 13B (yeast)
chrX_+_110814390 0.436 ENSMUST00000078229.3
 Pou3f4
POU domain, class 3, transcription factor 4
chrX_-_51018011 0.420 ENSMUST00000053593.7
 Rap2c
RAP2C, member of RAS oncogene family
chr13_-_67332525 0.398 ENSMUST00000168892.1
ENSMUST00000109735.2
 Zfp595

zinc finger protein 595

chr11_-_87826023 0.398 ENSMUST00000103177.3
 Lpo
lactoperoxidase
chr10_+_37139558 0.395 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr7_+_45062429 0.380 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
 Nosip



nitric oxide synthase interacting protein



chr4_-_133756769 0.369 ENSMUST00000008024.6
 Arid1a
AT rich interactive domain 1A (SWI-like)
chr11_+_20543307 0.364 ENSMUST00000093292.4
 Sertad2
SERTA domain containing 2
chr16_-_75766758 0.349 ENSMUST00000114244.1
ENSMUST00000046283.8
 Hspa13

heat shock protein 70 family, member 13

chr9_-_113708209 0.333 ENSMUST00000111861.3
ENSMUST00000035086.6
 Pdcd6ip

programmed cell death 6 interacting protein

chr11_+_62879449 0.312 ENSMUST00000014321.4
 Tvp23b
trans-golgi network vesicle protein 23B
chr3_-_113574758 0.310 ENSMUST00000106540.1
 Amy1
amylase 1, salivary
chr2_+_69789621 0.282 ENSMUST00000151298.1
ENSMUST00000028494.2
 Phospho2

phosphatase, orphan 2

chr1_-_9944103 0.268 ENSMUST00000182498.1
ENSMUST00000182742.1
ENSMUST00000182580.1
 Snhg6


small nucleolar RNA host gene (non-protein coding) 6


chr3_+_107291215 0.260 ENSMUST00000029502.7
 Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr16_+_44394771 0.255 ENSMUST00000099742.2
 Wdr52
WD repeat domain 52
chr5_+_25246775 0.249 ENSMUST00000144971.1
 Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr10_+_26822560 0.247 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr18_-_31911903 0.221 ENSMUST00000054984.6
 Sft2d3
SFT2 domain containing 3
chr11_-_109995775 0.221 ENSMUST00000020948.8
 Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr4_-_83285141 0.219 ENSMUST00000150522.1
 Ttc39b
tetratricopeptide repeat domain 39B
chr5_-_63968867 0.204 ENSMUST00000154169.1
 Rell1
RELT-like 1
chr1_+_170308802 0.196 ENSMUST00000056991.5
 1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr11_-_109995743 0.174 ENSMUST00000106669.2
 Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr7_+_45155865 0.172 ENSMUST00000107811.1
 Pih1d1
PIH1 domain containing 1
chr4_+_109343029 0.152 ENSMUST00000030281.5
 Eps15
epidermal growth factor receptor pathway substrate 15
chr19_+_8802486 0.145 ENSMUST00000172175.1
 Zbtb3
zinc finger and BTB domain containing 3
chr17_+_82539258 0.133 ENSMUST00000097278.3
 Gm6594
predicted pseudogene 6594
chr2_+_69789647 0.133 ENSMUST00000112266.1
 Phospho2
phosphatase, orphan 2
chr11_+_98863610 0.130 ENSMUST00000142414.1
ENSMUST00000037480.8
 Wipf2

WAS/WASL interacting protein family, member 2

chr16_-_16829276 0.106 ENSMUST00000023468.5
 Spag6
sperm associated antigen 6
chr19_+_58728887 0.091 ENSMUST00000048644.5
 Pnliprp1
pancreatic lipase related protein 1
chr3_+_96221111 0.081 ENSMUST00000090781.6
 Hist2h2be
histone cluster 2, H2be
chr11_+_115933282 0.079 ENSMUST00000140991.1
 Sap30bp
SAP30 binding protein
chr7_+_3645267 0.078 ENSMUST00000038913.9
 Cnot3
CCR4-NOT transcription complex, subunit 3
chr15_+_34453285 0.072 ENSMUST00000060894.7
 BC030476
cDNA sequence BC030476
chr19_-_58454435 0.066 ENSMUST00000169850.1
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr2_-_77703252 0.061 ENSMUST00000171063.1
 Zfp385b
zinc finger protein 385B
chr4_+_45848816 0.060 ENSMUST00000107782.1
ENSMUST00000030011.5
 1300002K09Rik

RIKEN cDNA 1300002K09 gene

chr14_+_29978337 0.058 ENSMUST00000016115.4
 Actr8
ARP8 actin-related protein 8
chr9_+_52047150 0.057 ENSMUST00000163153.1
 Rdx
radixin
chr11_+_23256566 0.039 ENSMUST00000136235.1
 Xpo1
exportin 1, CRM1 homolog (yeast)
chr11_-_115933464 0.028 ENSMUST00000021097.3
 Recql5
RecQ protein-like 5
chr1_-_184033998 0.022 ENSMUST00000050306.5
 1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr1_-_135585314 0.020 ENSMUST00000040599.8
ENSMUST00000067414.6
 Nav1

neuron navigator 1

chr7_-_103741322 0.016 ENSMUST00000051346.2
 Olfr629
olfactory receptor 629
chr2_-_177267036 0.016 ENSMUST00000108963.1
 Gm14409
predicted gene 14409
chr7_-_45062393 0.001 ENSMUST00000129101.1
 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.7 2.6 GO:0006538 glutamate catabolic process(GO:0006538)
0.6 3.7 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.6 1.8 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.5 3.8 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.4 4.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.4 3.1 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.3 3.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.3 1.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.3 3.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.3 0.6 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.3 0.8 GO:0060023 soft palate development(GO:0060023)
0.2 0.9 GO:0007412 axon target recognition(GO:0007412)
0.2 1.2 GO:1903056 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 2.5 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.6 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.1 1.3 GO:0070995 NADPH oxidation(GO:0070995)
0.1 3.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 5.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.1 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.4 GO:0006344 optic cup morphogenesis involved in camera-type eye development(GO:0002072) maintenance of chromatin silencing(GO:0006344)
0.0 0.6 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.4 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 1.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.2 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.5 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.2 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 1.5 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.2 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 2.0 GO:0048813 dendrite morphogenesis(GO:0048813)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.6 5.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 4.0 GO:0005883 neurofilament(GO:0005883)
0.3 3.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 3.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 3.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 3.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 2.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 1.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.3 6.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 3.8 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.3 1.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 3.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 0.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.4 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.1 2.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.3 GO:0070402 NADPH binding(GO:0070402)
0.1 3.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.5 GO:0016504 peptidase activator activity(GO:0016504)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)