Motif ID: Nr1h2

Z-value: 1.230


Transcription factors associated with Nr1h2:

Gene SymbolEntrez IDGene Name
Nr1h2 ENSMUSG00000060601.6 Nr1h2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1h2mm10_v2_chr7_-_44553901_445539550.731.5e-06Click!


Activity profile for motif Nr1h2.

activity profile for motif Nr1h2


Sorted Z-values histogram for motif Nr1h2

Sorted Z-values for motif Nr1h2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_97417730 14.700 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr4_-_53159885 13.545 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr6_+_90462562 11.183 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr8_-_84773381 9.653 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr2_+_102658640 7.695 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_97453204 7.146 ENSMUST00000050732.7
ENSMUST00000121987.1
Kctd14

potassium channel tetramerisation domain containing 14

chr11_+_55098104 7.007 ENSMUST00000000608.7
Gm2a
GM2 ganglioside activator protein
chr10_-_109823585 6.773 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr1_-_164458345 6.466 ENSMUST00000027863.7
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_+_112953955 5.365 ENSMUST00000182858.1
Rassf10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr17_-_79715034 4.757 ENSMUST00000024894.1
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr3_+_62419668 4.474 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr5_-_124327883 4.051 ENSMUST00000031344.6
Mphosph9
M-phase phosphoprotein 9
chr3_+_90514435 3.814 ENSMUST00000048138.6
ENSMUST00000181271.1
S100a13

S100 calcium binding protein A13

chr19_-_5845471 3.641 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr2_-_113829069 3.538 ENSMUST00000024005.7
Scg5
secretogranin V
chr5_-_120588613 3.429 ENSMUST00000046426.8
Tpcn1
two pore channel 1
chr5_+_123015010 3.386 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr13_-_12461432 3.348 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
Lgals8



lectin, galactose binding, soluble 8



chr11_+_93996082 3.198 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr11_-_60210410 3.143 ENSMUST00000144942.1
Srebf1
sterol regulatory element binding transcription factor 1
chrX_+_10717390 3.019 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chrX_+_10717451 2.863 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr5_+_107331157 2.629 ENSMUST00000031215.8
ENSMUST00000112677.3
Brdt

bromodomain, testis-specific

chr2_-_126876209 2.559 ENSMUST00000103224.3
Trpm7
transient receptor potential cation channel, subfamily M, member 7
chr1_+_57377593 2.549 ENSMUST00000042734.2
1700066M21Rik
RIKEN cDNA 1700066M21 gene
chr1_+_6214627 2.546 ENSMUST00000027040.6
Rb1cc1
RB1-inducible coiled-coil 1
chr5_+_26904682 2.495 ENSMUST00000120555.1
Dpp6
dipeptidylpeptidase 6
chrX_-_102644210 2.465 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
Phka1





phosphorylase kinase alpha 1





chr11_-_30025915 2.358 ENSMUST00000058902.5
Eml6
echinoderm microtubule associated protein like 6
chr7_-_27446599 2.336 ENSMUST00000011895.7
Sptbn4
spectrin beta, non-erythrocytic 4
chr15_+_65787023 2.126 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
Efr3a



EFR3 homolog A (S. cerevisiae)



chr9_-_42472198 2.125 ENSMUST00000128959.1
ENSMUST00000066148.5
ENSMUST00000138506.1
Tbcel


tubulin folding cofactor E-like


chrX_-_155216444 2.059 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr7_+_81523531 2.049 ENSMUST00000181903.1
2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr11_-_69948145 2.033 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr2_+_30266721 2.032 ENSMUST00000113645.1
ENSMUST00000133877.1
ENSMUST00000139719.1
ENSMUST00000113643.1
ENSMUST00000150695.1
Phyhd1




phytanoyl-CoA dioxygenase domain containing 1




chr1_+_135729147 2.007 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr18_+_37333853 1.977 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr6_-_134632388 1.941 ENSMUST00000047443.3
Mansc1
MANSC domain containing 1
chrX_-_155216338 1.929 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr2_+_155382186 1.851 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr7_+_81523555 1.838 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr15_+_85832301 1.766 ENSMUST00000146088.1
Ttc38
tetratricopeptide repeat domain 38
chr5_+_76840597 1.736 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr2_+_61593125 1.721 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chr1_+_58711488 1.713 ENSMUST00000097722.2
ENSMUST00000114313.1
Cflar

CASP8 and FADD-like apoptosis regulator

chr3_-_89245829 1.690 ENSMUST00000041022.8
Trim46
tripartite motif-containing 46
chr10_+_21993890 1.682 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr14_-_72602945 1.637 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr5_-_100159261 1.621 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr4_-_141538434 1.550 ENSMUST00000078886.3
Spen
SPEN homolog, transcriptional regulator (Drosophila)
chr5_+_124194894 1.549 ENSMUST00000159053.1
ENSMUST00000162577.1
Gm16338

predicted gene 16338

chr16_+_13940630 1.482 ENSMUST00000141971.1
ENSMUST00000124947.1
ENSMUST00000023360.7
ENSMUST00000143697.1
Mpv17l



Mpv17 transgene, kidney disease mutant-like



chr11_+_84179792 1.437 ENSMUST00000137500.2
ENSMUST00000130012.2
Acaca

acetyl-Coenzyme A carboxylase alpha

chr7_-_80371197 1.436 ENSMUST00000098346.3
Man2a2
mannosidase 2, alpha 2
chr6_+_124663027 1.432 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr2_+_155276297 1.432 ENSMUST00000029128.3
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr16_-_37384915 1.411 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr4_-_141538562 1.407 ENSMUST00000105786.2
Spen
SPEN homolog, transcriptional regulator (Drosophila)
chr15_+_79895017 1.399 ENSMUST00000023054.7
Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr2_+_61593077 1.387 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank

TRAF family member-associated Nf-kappa B activator

chr15_+_78877172 1.359 ENSMUST00000041587.7
Gga1
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr11_+_84179852 1.334 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr8_-_36249292 1.305 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr17_-_56716788 1.288 ENSMUST00000067931.5
Vmac
vimentin-type intermediate filament associated coiled-coil protein
chr12_-_87147883 1.282 ENSMUST00000037788.4
Pomt2
protein-O-mannosyltransferase 2
chr9_-_63399216 1.202 ENSMUST00000168665.1
2300009A05Rik
RIKEN cDNA 2300009A05 gene
chr12_+_105563123 1.188 ENSMUST00000001652.5
Bdkrb2
bradykinin receptor, beta 2
chr5_-_112392213 1.139 ENSMUST00000031291.7
Asphd2
aspartate beta-hydroxylase domain containing 2
chr10_-_81600857 1.137 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
Tle6


transducin-like enhancer of split 6, homolog of Drosophila E(spl)


chr9_+_77941274 1.083 ENSMUST00000134072.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr2_-_33087169 1.032 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr17_+_49428359 1.018 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
Mocs1


molybdenum cofactor synthesis 1


chr1_+_132506230 0.985 ENSMUST00000058167.1
Tmem81
transmembrane protein 81
chr14_-_6973818 0.882 ENSMUST00000166618.1
Gm6356
predicted gene 6356
chr12_+_87147703 0.735 ENSMUST00000063117.8
Gstz1
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr9_+_37208291 0.725 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr5_+_103754154 0.704 ENSMUST00000054979.3
Aff1
AF4/FMR2 family, member 1
chr8_+_4238815 0.682 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr15_-_89425795 0.663 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr10_-_53638269 0.657 ENSMUST00000164393.1
Fam184a
family with sequence similarity 184, member A
chr8_+_14095849 0.650 ENSMUST00000152652.1
ENSMUST00000133298.1
Dlgap2

discs, large (Drosophila) homolog-associated protein 2

chrX_-_53608979 0.641 ENSMUST00000123034.1
Gm14597
predicted gene 14597
chr17_-_25985641 0.632 ENSMUST00000041641.8
Capn15
calpain 15
chr2_+_131491764 0.610 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr10_+_18845071 0.593 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr2_+_154548888 0.578 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr4_-_44167580 0.577 ENSMUST00000098098.2
Rnf38
ring finger protein 38
chr17_-_35897073 0.532 ENSMUST00000150056.1
ENSMUST00000156817.1
ENSMUST00000146451.1
ENSMUST00000148482.1
2310061I04Rik



RIKEN cDNA 2310061I04 gene



chr1_+_33719863 0.528 ENSMUST00000088287.3
Rab23
RAB23, member RAS oncogene family
chr8_+_4238733 0.501 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr11_-_102556122 0.439 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr10_+_26822560 0.403 ENSMUST00000135866.1
Arhgap18
Rho GTPase activating protein 18
chr11_+_78245743 0.396 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr16_-_38550173 0.392 ENSMUST00000036210.6
Poglut1
protein O-glucosyltransferase 1
chr19_+_42247544 0.386 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr5_+_67306941 0.339 ENSMUST00000162372.1
ENSMUST00000113676.2
Slc30a9

solute carrier family 30 (zinc transporter), member 9

chr1_+_78657874 0.292 ENSMUST00000134566.1
ENSMUST00000142704.1
ENSMUST00000053760.5
Acsl3

Utp14b
acyl-CoA synthetase long-chain family member 3

UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast)
chr4_+_43641262 0.287 ENSMUST00000123351.1
ENSMUST00000128549.1
Npr2

natriuretic peptide receptor 2

chr5_-_122779278 0.283 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr2_+_131210501 0.281 ENSMUST00000110206.1
Ap5s1
adaptor-related protein 5 complex, sigma 1 subunit
chr2_+_30266513 0.279 ENSMUST00000091132.6
Phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr3_-_148989316 0.272 ENSMUST00000098518.2
Lphn2
latrophilin 2
chr2_+_155381808 0.258 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr5_-_136565432 0.248 ENSMUST00000176172.1
Cux1
cut-like homeobox 1
chr5_+_37185897 0.203 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr2_+_131210363 0.160 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
Ap5s1


adaptor-related protein 5 complex, sigma 1 subunit


chr2_+_156421083 0.142 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
Epb4.1l1


erythrocyte protein band 4.1-like 1


chr4_-_46389391 0.142 ENSMUST00000086563.4
ENSMUST00000030015.5
5830415F09Rik

RIKEN cDNA 5830415F09 gene

chr13_+_55600055 0.086 ENSMUST00000133176.1
ENSMUST00000064701.6
B4galt7

xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)

chr2_-_164911586 0.084 ENSMUST00000041361.7
Zfp335
zinc finger protein 335
chr19_+_53142756 0.071 ENSMUST00000050096.7
Add3
adducin 3 (gamma)
chr8_+_18846251 0.063 ENSMUST00000149565.1
ENSMUST00000033847.4
Agpat5

1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.5 GO:0055099 regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
2.2 6.5 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
1.6 4.8 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
1.4 7.0 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
1.3 4.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.3 7.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
1.3 3.8 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.9 2.8 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.8 11.2 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.8 9.0 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.7 9.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6 2.6 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.6 1.7 GO:0014891 striated muscle atrophy(GO:0014891)
0.6 14.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.6 3.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.4 1.7 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.4 3.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.4 1.2 GO:1902219 maintenance of blood-brain barrier(GO:0035633) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.4 2.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 1.5 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 0.7 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.2 1.4 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.2 3.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 3.6 GO:0030575 nuclear body organization(GO:0030575)
0.2 4.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 1.0 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2 0.6 GO:0046208 spermine catabolic process(GO:0046208)
0.2 2.6 GO:0007141 male meiosis I(GO:0007141)
0.2 1.4 GO:0006013 mannose metabolic process(GO:0006013)
0.2 3.5 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 2.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.6 GO:0002934 desmosome organization(GO:0002934)
0.1 1.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 2.5 GO:0019228 neuronal action potential(GO:0019228)
0.1 3.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 1.6 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.4 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.5 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 2.0 GO:0070527 platelet aggregation(GO:0070527)
0.0 2.1 GO:0000045 autophagosome assembly(GO:0000045)
0.0 1.4 GO:1901998 toxin transport(GO:1901998)
0.0 1.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 2.5 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.5 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.0 2.1 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.0 0.1 GO:0043206 extracellular fibril organization(GO:0043206)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 13.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.6 2.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 2.1 GO:0001533 cornified envelope(GO:0001533)
0.5 3.6 GO:0042382 paraspeckles(GO:0042382)
0.4 1.7 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.4 2.3 GO:0008091 spectrin(GO:0008091)
0.4 1.1 GO:0097447 dendritic tree(GO:0097447)
0.4 2.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.3 1.3 GO:0045098 type III intermediate filament(GO:0045098)
0.3 1.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 7.7 GO:0030673 axolemma(GO:0030673)
0.2 2.6 GO:0043196 varicosity(GO:0043196)
0.1 2.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 7.4 GO:0005776 autophagosome(GO:0005776)
0.0 1.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 11.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 4.6 GO:0030141 secretory granule(GO:0030141)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 6.9 GO:0005874 microtubule(GO:0005874)
0.0 4.4 GO:0005635 nuclear envelope(GO:0005635)
0.0 6.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0036126 sperm flagellum(GO:0036126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.5 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
1.9 7.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.4 7.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
1.3 4.0 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
1.1 3.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
1.0 4.8 GO:0070330 aromatase activity(GO:0070330)
0.9 2.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.6 6.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.6 3.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.5 2.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.4 1.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 2.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.3 1.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.3 3.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 3.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 1.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 1.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 1.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.6 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 1.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 1.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 2.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 2.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 1.4 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 3.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 3.2 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 10.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 13.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 2.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 8.2 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 3.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.2 GO:0008022 protein C-terminus binding(GO:0008022)