Motif ID: Nr1h4

Z-value: 0.881


Transcription factors associated with Nr1h4:

Gene SymbolEntrez IDGene Name
Nr1h4 ENSMUSG00000047638.9 Nr1h4



Activity profile for motif Nr1h4.

activity profile for motif Nr1h4


Sorted Z-values histogram for motif Nr1h4

Sorted Z-values for motif Nr1h4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h4

PNG image of the network

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Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_94179089 6.214 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr9_+_44107268 4.910 ENSMUST00000114821.2
ENSMUST00000114818.2
 C1qtnf5

C1q and tumor necrosis factor related protein 5

chr7_-_31055594 4.899 ENSMUST00000039909.6
 Fxyd1
FXYD domain-containing ion transport regulator 1
chr14_-_30923754 4.848 ENSMUST00000006697.8
 Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr9_+_44107286 4.691 ENSMUST00000152956.1
ENSMUST00000114815.1
 C1qtnf5

C1q and tumor necrosis factor related protein 5

chr9_+_50752758 4.669 ENSMUST00000034562.7
 Cryab
crystallin, alpha B
chr1_+_172341197 4.587 ENSMUST00000056136.3
 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr14_-_30923547 4.520 ENSMUST00000170415.1
 Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr14_-_26170283 4.446 ENSMUST00000100809.4
 Plac9b
placenta specific 9b
chr9_+_44107226 3.477 ENSMUST00000114816.1
 C1qtnf5
C1q and tumor necrosis factor related protein 5
chr19_+_4594312 3.448 ENSMUST00000113825.2
 Pcx
pyruvate carboxylase
chr11_+_3983704 3.369 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr4_+_117849193 3.311 ENSMUST00000132043.2
ENSMUST00000169990.1
 Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr10_+_23894688 3.289 ENSMUST00000041416.7
 Vnn1
vanin 1
chr7_-_105482197 3.254 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr4_+_117849361 3.218 ENSMUST00000163288.1
 Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_-_162859684 3.053 ENSMUST00000131058.1
 Fmo1
flavin containing monooxygenase 1
chr7_-_44670820 2.922 ENSMUST00000048102.7
 Myh14
myosin, heavy polypeptide 14
chr2_-_152951547 2.739 ENSMUST00000037715.6
 Dusp15
dual specificity phosphatase-like 15
chr4_+_53440388 2.726 ENSMUST00000102911.3
ENSMUST00000107646.2
 Slc44a1

solute carrier family 44, member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 13.1 GO:0070206 protein trimerization(GO:0070206)
0.3 9.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
2.2 6.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.9 6.2 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
1.8 5.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 5.0 GO:0046330 positive regulation of JNK cascade(GO:0046330)
1.6 4.9 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.8 4.7 GO:0007021 tubulin complex assembly(GO:0007021)
1.5 4.6 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
1.1 4.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 4.3 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 3.9 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
1.1 3.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.1 3.3 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.3 3.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 3.1 GO:0009404 toxin metabolic process(GO:0009404)
1.0 2.9 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 2.9 GO:0071625 vocalization behavior(GO:0071625)
0.5 2.7 GO:0015871 choline transport(GO:0015871)
0.0 2.4 GO:0006821 chloride transport(GO:0006821)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 7.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 5.0 GO:0000139 Golgi membrane(GO:0000139)
1.6 4.7 GO:0097512 cardiac myofibril(GO:0097512)
0.4 4.6 GO:0097449 astrocyte projection(GO:0097449)
0.1 4.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 4.1 GO:0098793 presynapse(GO:0098793)
0.1 3.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.3 GO:0005901 caveola(GO:0005901)
0.6 2.9 GO:1990761 growth cone lamellipodium(GO:1990761)
0.5 2.9 GO:0097513 myosin II filament(GO:0097513)
0.0 1.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 1.1 GO:0010008 endosome membrane(GO:0010008)
0.1 1.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.1 6.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 6.2 GO:0005507 copper ion binding(GO:0005507)
1.4 5.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 5.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.5 4.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 4.7 GO:0017080 sodium channel regulator activity(GO:0017080)
1.5 4.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.8 4.6 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 4.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.6 3.4 GO:0009374 biotin binding(GO:0009374)
0.7 3.3 GO:0034235 GPI anchor binding(GO:0034235)
0.6 3.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 3.0 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.7 2.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)