Motif ID: Nr1h4
Z-value: 0.881
Transcription factors associated with Nr1h4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nr1h4 | ENSMUSG00000047638.9 | Nr1h4 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 6.5 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 1.8 | 5.4 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 1.6 | 4.9 | GO:1903795 | regulation of inorganic anion transmembrane transport(GO:1903795) |
| 1.5 | 4.6 | GO:0051933 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
| 1.1 | 3.4 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 1.1 | 4.6 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 1.1 | 3.3 | GO:0043465 | regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003) |
| 1.0 | 2.9 | GO:1904049 | regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 0.9 | 6.2 | GO:0010273 | detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169) |
| 0.8 | 4.7 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.6 | 1.8 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.5 | 2.7 | GO:0015871 | choline transport(GO:0015871) |
| 0.4 | 1.6 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.4 | 1.1 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
| 0.4 | 1.1 | GO:1903525 | regulation of membrane tubulation(GO:1903525) |
| 0.3 | 9.4 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.3 | 0.9 | GO:1902071 | positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
| 0.3 | 3.1 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.3 | 3.3 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.3 | 1.2 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.3 | 13.1 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.2 | 1.0 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
| 0.2 | 0.8 | GO:0006742 | NADP catabolic process(GO:0006742) NAD biosynthetic process(GO:0009435) pyridine nucleotide catabolic process(GO:0019364) |
| 0.2 | 1.8 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.2 | 0.5 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.1 | 0.4 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.1 | 2.9 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 0.3 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.1 | 0.2 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
| 0.1 | 0.8 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 0.6 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 3.9 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.1 | 0.5 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 0.3 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.1 | 0.9 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.1 | 0.4 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
| 0.1 | 0.2 | GO:1903546 | microtubule anchoring at centrosome(GO:0034454) negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) protein localization to photoreceptor outer segment(GO:1903546) |
| 0.0 | 0.2 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
| 0.0 | 1.4 | GO:0010771 | negative regulation of cell morphogenesis involved in differentiation(GO:0010771) |
| 0.0 | 5.0 | GO:0046330 | positive regulation of JNK cascade(GO:0046330) |
| 0.0 | 1.2 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 2.4 | GO:0006821 | chloride transport(GO:0006821) |
| 0.0 | 0.2 | GO:0046103 | ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103) |
| 0.0 | 2.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 4.3 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
| 0.0 | 1.5 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.2 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.0 | 0.6 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 2.2 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.0 | 0.1 | GO:0048597 | post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.0 | 0.6 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.6 | GO:0021795 | cerebral cortex cell migration(GO:0021795) |
| 0.0 | 1.4 | GO:0006073 | glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042) |
| 0.0 | 1.9 | GO:0016573 | histone acetylation(GO:0016573) |
| 0.0 | 0.4 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.7 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.7 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.6 | 2.9 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.5 | 2.9 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.4 | 4.6 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.2 | 1.4 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.2 | 7.0 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 9.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 0.4 | GO:0043512 | inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512) |
| 0.1 | 3.9 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.1 | 0.8 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.1 | 0.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 1.5 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 0.9 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 4.6 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.1 | 1.0 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 1.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.3 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
| 0.0 | 0.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 0.7 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 3.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 3.3 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.1 | GO:1990879 | CST complex(GO:1990879) |
| 0.0 | 0.2 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.0 | 0.9 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.2 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 5.0 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 1.1 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 4.1 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 1.1 | GO:0010008 | endosome membrane(GO:0010008) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.6 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 1.4 | 5.4 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 1.1 | 6.5 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.8 | 4.6 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.7 | 2.7 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.7 | 3.3 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.6 | 3.1 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.6 | 3.4 | GO:0009374 | biotin binding(GO:0009374) |
| 0.5 | 4.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.3 | 1.0 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.3 | 0.9 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.3 | 1.2 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.3 | 1.1 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
| 0.3 | 1.1 | GO:0004096 | catalase activity(GO:0004096) |
| 0.3 | 1.8 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.3 | 1.8 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.2 | 9.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 1.4 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.2 | 1.4 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
| 0.2 | 2.1 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.2 | 0.9 | GO:0043842 | Kdo transferase activity(GO:0043842) |
| 0.1 | 2.2 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 6.2 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.1 | 0.5 | GO:0008488 | gamma-glutamyl carboxylase activity(GO:0008488) |
| 0.1 | 0.8 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 4.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 2.9 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.9 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 4.2 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.1 | 0.8 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
| 0.1 | 5.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 2.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 1.5 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.1 | 2.0 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.1 | 0.2 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 0.6 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 0.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 0.4 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 0.4 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.0 | 3.0 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.7 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.2 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.0 | 0.8 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.0 | 0.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 1.2 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.1 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 1.6 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 0.8 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 1.1 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 1.5 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 1.6 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 0.1 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.0 | 0.6 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
