Motif ID: Nr2c1

Z-value: 0.586


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_941480230.115.4e-01Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 102 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_110768169 3.062 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr10_+_58813359 2.475 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr11_-_3504766 2.416 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr9_-_29411736 2.284 ENSMUST00000115236.1
Ntm
neurotrimin
chr6_+_22875496 2.273 ENSMUST00000090568.3
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chrX_+_10485121 2.169 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr4_-_46991842 2.140 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr15_+_81811414 2.004 ENSMUST00000023024.7
Tef
thyrotroph embryonic factor
chr1_-_155417283 1.972 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr2_-_29253001 1.966 ENSMUST00000071201.4
Ntng2
netrin G2
chr9_-_29412204 1.956 ENSMUST00000115237.1
Ntm
neurotrimin
chr15_+_80091320 1.954 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1

synaptogyrin 1

chr11_+_3488275 1.673 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr1_-_120120138 1.648 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr7_+_46397648 1.600 ENSMUST00000160433.1
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr10_+_93589413 1.514 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr12_+_83987854 1.370 ENSMUST00000021649.7
Acot2
acyl-CoA thioesterase 2
chr12_-_83487708 1.347 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr4_-_82859571 1.298 ENSMUST00000156055.1
ENSMUST00000030110.8
Zdhhc21

zinc finger, DHHC domain containing 21

chr1_-_58586191 1.243 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.1 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.4 3.1 GO:0032264 IMP salvage(GO:0032264)
0.5 2.6 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 2.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.8 2.3 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.1 2.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 2.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 2.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 1.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 1.6 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.2 1.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 1.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.3 GO:0098792 xenophagy(GO:0098792)
0.4 1.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.2 1.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.8 GO:0001553 luteinization(GO:0001553)
0.0 0.8 GO:0006493 protein O-linked glycosylation(GO:0006493)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.8 2.3 GO:0072534 perineuronal net(GO:0072534)
0.4 2.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.1 1.6 GO:0030673 axolemma(GO:0030673)
0.1 1.3 GO:0071565 nBAF complex(GO:0071565)
0.1 1.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.1 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 2.6 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.8 2.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 2.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.4 2.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 2.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.9 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 1.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.1 GO:0008430 selenium binding(GO:0008430)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.1 GO:0061733 peptide N-acetyltransferase activity(GO:0034212) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.2 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.7 GO:0004103 choline kinase activity(GO:0004103)