Motif ID: Nr2c1

Z-value: 0.586


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_941480230.115.4e-01Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_110768169 3.062 ENSMUST00000170374.1
 Ampd3
adenosine monophosphate deaminase 3
chr10_+_58813359 2.475 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr11_-_3504766 2.416 ENSMUST00000044507.5
 Inpp5j
inositol polyphosphate 5-phosphatase J
chr9_-_29411736 2.284 ENSMUST00000115236.1
 Ntm
neurotrimin
chr6_+_22875496 2.273 ENSMUST00000090568.3
 Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chrX_+_10485121 2.169 ENSMUST00000076354.6
ENSMUST00000115526.1
 Tspan7

tetraspanin 7

chr4_-_46991842 2.140 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr15_+_81811414 2.004 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr1_-_155417283 1.972 ENSMUST00000027741.5
 Xpr1
xenotropic and polytropic retrovirus receptor 1
chr2_-_29253001 1.966 ENSMUST00000071201.4
 Ntng2
netrin G2
chr9_-_29412204 1.956 ENSMUST00000115237.1
 Ntm
neurotrimin
chr15_+_80091320 1.954 ENSMUST00000009728.6
ENSMUST00000009727.5
 Syngr1

synaptogyrin 1

chr11_+_3488275 1.673 ENSMUST00000064265.6
 Pla2g3
phospholipase A2, group III
chr1_-_120120138 1.648 ENSMUST00000112648.1
ENSMUST00000128408.1
 Dbi

diazepam binding inhibitor

chr7_+_46397648 1.600 ENSMUST00000160433.1
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr10_+_93589413 1.514 ENSMUST00000181835.1
 4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr12_+_83987854 1.370 ENSMUST00000021649.7
 Acot2
acyl-CoA thioesterase 2
chr12_-_83487708 1.347 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr4_-_82859571 1.298 ENSMUST00000156055.1
ENSMUST00000030110.8
 Zdhhc21

zinc finger, DHHC domain containing 21

chr1_-_58586191 1.243 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
 Fam126b



family with sequence similarity 126, member B



chr9_+_65101453 1.231 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
 Igdcc4


immunoglobulin superfamily, DCC subclass, member 4


chr4_+_127172866 1.133 ENSMUST00000106094.2
 Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr15_+_3270767 1.060 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chrX_+_100729917 1.055 ENSMUST00000019503.7
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr5_+_117120120 1.052 ENSMUST00000111978.1
 Taok3
TAO kinase 3
chr1_+_93215899 1.002 ENSMUST00000138595.1
 E030010N08Rik
RIKEN cDNA E030010N08 gene
chr5_+_105519388 0.954 ENSMUST00000067924.6
ENSMUST00000150981.1
 Lrrc8c

leucine rich repeat containing 8 family, member C

chr1_-_120120937 0.914 ENSMUST00000151708.1
 Dbi
diazepam binding inhibitor
chr4_+_133039482 0.891 ENSMUST00000105914.1
 Ahdc1
AT hook, DNA binding motif, containing 1
chr16_-_44139630 0.885 ENSMUST00000137557.1
ENSMUST00000147025.1
 Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr4_+_156215920 0.868 ENSMUST00000105572.1
 2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr6_-_142964404 0.849 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr13_+_84222286 0.804 ENSMUST00000057495.8
 Tmem161b
transmembrane protein 161B
chr1_-_58973421 0.793 ENSMUST00000173590.1
ENSMUST00000027186.5
 Trak2

trafficking protein, kinesin binding 2

chr15_+_89429560 0.786 ENSMUST00000168646.1
 C730034F03Rik
RIKEN cDNA C730034F03 gene
chr3_+_68572245 0.772 ENSMUST00000170788.2
 Schip1
schwannomin interacting protein 1
chr11_-_26210553 0.768 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr17_-_46032366 0.733 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
 Vegfa


vascular endothelial growth factor A


chr9_-_21037775 0.721 ENSMUST00000180870.1
 Gm26592
predicted gene, 26592
chr15_-_89429093 0.700 ENSMUST00000170460.1
 Chkb
choline kinase beta
chr17_-_35235755 0.692 ENSMUST00000048994.6
 Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr17_-_35910032 0.689 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
 Atat1




alpha tubulin acetyltransferase 1




chr1_+_58973521 0.672 ENSMUST00000114296.1
ENSMUST00000027185.4
 Stradb

STE20-related kinase adaptor beta

chr15_-_79141197 0.664 ENSMUST00000169604.1
 1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr16_+_44139821 0.657 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
 Naa50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr6_+_125145235 0.640 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
 Iffo1



intermediate filament family orphan 1



chr1_+_180726019 0.589 ENSMUST00000027780.4
 Acbd3
acyl-Coenzyme A binding domain containing 3
chr9_+_118506226 0.583 ENSMUST00000084820.4
 Golga4
golgi autoantigen, golgin subfamily a, 4
chr4_+_129461581 0.558 ENSMUST00000048162.8
ENSMUST00000138013.1
 Bsdc1

BSD domain containing 1

chr10_+_127705170 0.510 ENSMUST00000079590.5
 Myo1a
myosin IA
chr10_-_86498836 0.474 ENSMUST00000120638.1
 Syn3
synapsin III
chr2_+_130406478 0.448 ENSMUST00000055421.4
 Tmem239
transmembrane 239
chrX_-_59567348 0.421 ENSMUST00000124402.1
 Fgf13
fibroblast growth factor 13
chr13_-_93192270 0.410 ENSMUST00000048702.5
 Papd4
PAP associated domain containing 4
chr7_+_45896941 0.403 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr11_+_62281457 0.366 ENSMUST00000101075.4
ENSMUST00000050646.6
 Ttc19

tetratricopeptide repeat domain 19

chr17_-_35909626 0.361 ENSMUST00000141132.1
 Atat1
alpha tubulin acetyltransferase 1
chr2_-_164804876 0.349 ENSMUST00000103094.4
ENSMUST00000017451.6
 Acot8

acyl-CoA thioesterase 8

chr15_-_89425795 0.349 ENSMUST00000168376.1
 Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr15_+_86214431 0.346 ENSMUST00000063414.8
 Tbc1d22a
TBC1 domain family, member 22a
chr11_-_107337556 0.345 ENSMUST00000040380.6
 Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr19_-_45998479 0.327 ENSMUST00000045396.7
 9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr16_-_44139196 0.293 ENSMUST00000063661.6
ENSMUST00000114666.2
 Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr12_+_37241633 0.291 ENSMUST00000049874.7
 Agmo
alkylglycerol monooxygenase
chr4_-_41048124 0.289 ENSMUST00000030136.6
 Aqp7
aquaporin 7
chr11_-_50325599 0.282 ENSMUST00000179865.1
ENSMUST00000020637.8
 Canx

calnexin

chr19_-_6921753 0.274 ENSMUST00000173635.1
 Esrra
estrogen related receptor, alpha
chr6_+_124663027 0.257 ENSMUST00000004381.7
 Lpcat3
lysophosphatidylcholine acyltransferase 3
chr5_-_137741601 0.247 ENSMUST00000119498.1
ENSMUST00000061789.7
 Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr17_-_51810866 0.234 ENSMUST00000176669.1
 Satb1
special AT-rich sequence binding protein 1
chr3_+_32529452 0.225 ENSMUST00000091257.4
 Mfn1
mitofusin 1
chr19_-_6921804 0.211 ENSMUST00000025906.4
 Esrra
estrogen related receptor, alpha
chr5_-_5265224 0.192 ENSMUST00000115450.1
 Cdk14
cyclin-dependent kinase 14
chr4_+_137993016 0.173 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
 Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr2_+_153345809 0.162 ENSMUST00000109790.1
 Asxl1
additional sex combs like 1
chr10_+_41519493 0.161 ENSMUST00000019962.8
 Cd164
CD164 antigen
chr3_+_86224665 0.158 ENSMUST00000107635.1
 Lrba
LPS-responsive beige-like anchor
chr14_+_20674311 0.156 ENSMUST00000048657.8
 Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr7_-_28598140 0.144 ENSMUST00000108283.1
ENSMUST00000040531.8
 Pak4
Samd4b
p21 protein (Cdc42/Rac)-activated kinase 4
sterile alpha motif domain containing 4B
chr10_-_4432312 0.141 ENSMUST00000126102.1
ENSMUST00000131853.1
ENSMUST00000042251.4
 Rmnd1


required for meiotic nuclear division 1 homolog (S. cerevisiae)


chr1_+_195017399 0.138 ENSMUST00000181273.1
 A330023F24Rik
RIKEN cDNA A330023F24 gene
chr1_-_156939387 0.128 ENSMUST00000171292.1
 Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr8_-_123894736 0.122 ENSMUST00000034453.4
 Acta1
actin, alpha 1, skeletal muscle
chr12_+_61523889 0.118 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr1_-_172632931 0.118 ENSMUST00000027826.5
 Dusp23
dual specificity phosphatase 23
chr11_-_62281342 0.118 ENSMUST00000072916.4
 Zswim7
zinc finger SWIM-type containing 7
chr10_-_86498872 0.102 ENSMUST00000121789.1
 Syn3
synapsin III
chr19_+_4097392 0.098 ENSMUST00000174514.1
ENSMUST00000174149.1
 Cdk2ap2

CDK2-associated protein 2

chr2_+_92375306 0.098 ENSMUST00000028650.8
 Pex16
peroxisomal biogenesis factor 16
chr13_+_31558157 0.091 ENSMUST00000042118.8
 Foxq1
forkhead box Q1
chr3_+_32529532 0.081 ENSMUST00000147350.1
 Mfn1
mitofusin 1
chr1_-_156718894 0.058 ENSMUST00000086153.6
 Fam20b
family with sequence similarity 20, member B
chr11_-_97766508 0.054 ENSMUST00000107579.1
ENSMUST00000018685.2
 Cwc25

CWC25 spliceosome-associated protein homolog (S. cerevisiae)

chr1_-_74544275 0.046 ENSMUST00000044260.4
 Usp37
ubiquitin specific peptidase 37
chr3_+_58525821 0.034 ENSMUST00000029387.8
 Eif2a
eukaryotic translation initiation factor 2A
chr11_-_76577701 0.026 ENSMUST00000176179.1
 Abr
active BCR-related gene
chr17_+_34850373 0.022 ENSMUST00000097343.4
ENSMUST00000173357.1
ENSMUST00000173065.1
ENSMUST00000165953.2
 Nelfe



negative elongation factor complex member E, Rdbp



chr7_+_45897429 0.021 ENSMUST00000140243.1
 Tmem143
transmembrane protein 143
chr17_-_34028044 0.015 ENSMUST00000045467.7
ENSMUST00000114303.3
 H2-Ke6

H2-K region expressed gene 6

chr2_+_22895583 0.009 ENSMUST00000152170.1
 Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr1_+_74284930 0.008 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
 Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr19_+_46152505 0.006 ENSMUST00000026254.7
 Gbf1
golgi-specific brefeldin A-resistance factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.5 2.6 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.4 1.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.4 3.1 GO:0032264 IMP salvage(GO:0032264)
0.4 1.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.3 2.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.7 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.2 1.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.2 1.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 2.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 2.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.7 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 2.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0015793 glycerol transport(GO:0015793)
0.1 0.7 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.8 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.6 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 1.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.3 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.5 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.7 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 4.1 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.8 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.5 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 1.3 GO:0098792 xenophagy(GO:0098792)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0072534 perineuronal net(GO:0072534)
0.4 2.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.1 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.6 GO:0030673 axolemma(GO:0030673)
0.1 1.3 GO:0071565 nBAF complex(GO:0071565)
0.0 2.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 4.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.6 2.6 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.4 3.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 2.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 2.0 GO:0001618 virus receptor activity(GO:0001618)
0.2 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.7 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.1 GO:0008430 selenium binding(GO:0008430)
0.1 2.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.9 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.1 GO:0061733 peptide N-acetyltransferase activity(GO:0034212) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)