Motif ID: Nr2c2

Z-value: 1.026


Transcription factors associated with Nr2c2:

Gene SymbolEntrez IDGene Name
Nr2c2 ENSMUSG00000005893.8 Nr2c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c2mm10_v2_chr6_+_92091378_92091390-0.873.0e-11Click!


Activity profile for motif Nr2c2.

activity profile for motif Nr2c2


Sorted Z-values histogram for motif Nr2c2

Sorted Z-values for motif Nr2c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_38395980 5.453 ENSMUST00000054098.2
 Slc35g1
solute carrier family 35, member G1
chr11_-_90002881 4.982 ENSMUST00000020864.8
 Pctp
phosphatidylcholine transfer protein
chr1_+_12718496 4.778 ENSMUST00000088585.3
 Sulf1
sulfatase 1
chr9_-_22135675 3.661 ENSMUST00000165735.1
 Acp5
acid phosphatase 5, tartrate resistant
chr10_+_88147061 3.575 ENSMUST00000169309.1
 Nup37
nucleoporin 37
chr1_-_133424377 3.569 ENSMUST00000153799.1
 Sox13
SRY-box containing gene 13
chr10_+_88146992 3.491 ENSMUST00000052355.7
 Nup37
nucleoporin 37
chr2_+_165655237 3.425 ENSMUST00000063433.7
 Eya2
eyes absent 2 homolog (Drosophila)
chr4_+_101419277 3.286 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
 Ak4


adenylate kinase 4


chr5_-_137611372 3.258 ENSMUST00000054564.6
 Pcolce
procollagen C-endopeptidase enhancer protein
chr7_-_126800036 3.213 ENSMUST00000133514.1
ENSMUST00000151137.1
 Aldoa

aldolase A, fructose-bisphosphate

chr7_-_126800354 3.208 ENSMUST00000106348.1
 Aldoa
aldolase A, fructose-bisphosphate
chr13_-_24761861 3.169 ENSMUST00000006898.3
ENSMUST00000110382.2
 Gmnn

geminin

chr9_+_65630552 3.147 ENSMUST00000055844.8
 Rbpms2
RNA binding protein with multiple splicing 2
chr1_+_166254095 3.021 ENSMUST00000111416.1
 Ildr2
immunoglobulin-like domain containing receptor 2
chr6_-_95718800 3.013 ENSMUST00000079847.5
 Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr5_-_137611429 2.909 ENSMUST00000031731.7
 Pcolce
procollagen C-endopeptidase enhancer protein
chr7_+_104218787 2.866 ENSMUST00000098180.3
 Trim6
tripartite motif-containing 6
chr1_-_163289214 2.854 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1
chr4_+_101419696 2.817 ENSMUST00000131397.1
ENSMUST00000133055.1
 Ak4

adenylate kinase 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 244 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.8 GO:0051028 mRNA transport(GO:0051028)
0.6 6.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.8 5.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 5.1 GO:0046033 AMP metabolic process(GO:0046033)
0.0 5.1 GO:0051301 cell division(GO:0051301)
0.1 5.0 GO:0015914 phospholipid transport(GO:0015914)
1.2 4.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.5 4.6 GO:0030421 defecation(GO:0030421)
0.8 4.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.4 4.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 4.2 GO:0007498 mesoderm development(GO:0007498)
0.4 4.1 GO:0006105 succinate metabolic process(GO:0006105)
0.8 3.9 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.6 3.8 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 3.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 3.8 GO:0006446 regulation of translational initiation(GO:0006446)
0.3 3.6 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.3 3.6 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.5 3.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.3 3.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 12.0 GO:0031012 extracellular matrix(GO:0031012)
0.6 7.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 7.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.5 6.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 5.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 5.8 GO:0005657 replication fork(GO:0005657)
0.1 4.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 4.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.4 4.0 GO:0061574 ASAP complex(GO:0061574)
0.5 3.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.6 3.5 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 3.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 3.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 3.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 2.8 GO:0071203 WASH complex(GO:0071203)
0.0 2.7 GO:0005840 ribosome(GO:0005840)
0.1 2.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 177 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 8.4 GO:0016504 peptidase activator activity(GO:0016504)
1.1 6.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.0 6.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.5 5.2 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.8 5.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
1.0 4.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.5 4.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 4.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 4.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 4.3 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.2 4.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 4.3 GO:0030792 methylarsonite methyltransferase activity(GO:0030792)
0.1 4.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 3.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
1.2 3.6 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 3.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 3.4 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 3.2 GO:0043425 bHLH transcription factor binding(GO:0043425) E-box binding(GO:0070888)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)