Motif ID: Nr2e1

Z-value: 0.347


Transcription factors associated with Nr2e1:

Gene SymbolEntrez IDGene Name
Nr2e1 ENSMUSG00000019803.5 Nr2e1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2e1mm10_v2_chr10_-_42583628_425836390.115.6e-01Click!


Activity profile for motif Nr2e1.

activity profile for motif Nr2e1


Sorted Z-values histogram for motif Nr2e1

Sorted Z-values for motif Nr2e1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_32028989 1.430 ENSMUST00000022460.4
 Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr4_+_33924632 1.195 ENSMUST00000057188.6
 Cnr1
cannabinoid receptor 1 (brain)
chr9_-_58158498 0.672 ENSMUST00000168864.2
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr2_-_73386396 0.647 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
 Gpr155


G protein-coupled receptor 155


chr7_-_80405425 0.502 ENSMUST00000107362.3
ENSMUST00000135306.1
 Furin

furin (paired basic amino acid cleaving enzyme)

chr3_+_26331150 0.392 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene
chr8_+_36489191 0.343 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr1_+_24678536 0.321 ENSMUST00000095062.3
 Lmbrd1
LMBR1 domain containing 1
chr1_-_53785214 0.303 ENSMUST00000027263.7
 Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
chr3_-_146781351 0.303 ENSMUST00000005164.7
 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr9_-_71163224 0.278 ENSMUST00000074465.2
 Aqp9
aquaporin 9
chr4_+_32238950 0.278 ENSMUST00000037416.6
 Bach2
BTB and CNC homology 2
chr15_+_41830921 0.268 ENSMUST00000166917.1
 Oxr1
oxidation resistance 1
chr18_+_34840575 0.258 ENSMUST00000043484.7
 Reep2
receptor accessory protein 2
chr9_-_42457594 0.247 ENSMUST00000125995.1
 Tbcel
tubulin folding cofactor E-like
chr17_+_33919332 0.233 ENSMUST00000025161.7
 Tapbp
TAP binding protein
chr5_-_88527841 0.226 ENSMUST00000087033.3
 Igj
immunoglobulin joining chain
chr2_-_23040177 0.214 ENSMUST00000114544.3
ENSMUST00000139038.1
ENSMUST00000126112.1
ENSMUST00000178908.1
ENSMUST00000078977.7
ENSMUST00000140164.1
ENSMUST00000149719.1
 Abi1






abl-interactor 1






chr2_-_23040137 0.207 ENSMUST00000091394.6
ENSMUST00000093171.6
 Abi1

abl-interactor 1

chr2_-_23040092 0.189 ENSMUST00000153931.1
ENSMUST00000123948.1
 Abi1

abl-interactor 1

chr17_+_32685610 0.183 ENSMUST00000168171.1
 Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chrX_-_95658379 0.171 ENSMUST00000119640.1
 Zc4h2
zinc finger, C4H2 domain containing
chr17_+_32685655 0.142 ENSMUST00000008801.6
 Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr12_-_87147883 0.139 ENSMUST00000037788.4
 Pomt2
protein-O-mannosyltransferase 2
chr4_-_63403330 0.121 ENSMUST00000035724.4
 Akna
AT-hook transcription factor
chr10_+_18469958 0.087 ENSMUST00000162891.1
ENSMUST00000100054.3
 Nhsl1

NHS-like 1

chr6_+_126939957 0.074 ENSMUST00000032497.3
 D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chrX_-_95658392 0.069 ENSMUST00000120620.1
 Zc4h2
zinc finger, C4H2 domain containing
chrX_-_95658416 0.065 ENSMUST00000044382.6
 Zc4h2
zinc finger, C4H2 domain containing
chr12_+_111166349 0.060 ENSMUST00000117269.1
 Traf3
TNF receptor-associated factor 3
chrM_+_7005 0.055 ENSMUST00000082405.1
 mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr7_+_131542867 0.052 ENSMUST00000046093.5
 Hmx3
H6 homeobox 3
chr12_+_111166536 0.029 ENSMUST00000060274.6
 Traf3
TNF receptor-associated factor 3
chr12_+_111166413 0.002 ENSMUST00000021706.4
 Traf3
TNF receptor-associated factor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0031622 positive regulation of fever generation(GO:0031622)
0.1 0.5 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.3 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.0 0.2 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)