Motif ID: Nr2e3

Z-value: 1.431


Transcription factors associated with Nr2e3:

Gene SymbolEntrez IDGene Name
Nr2e3 ENSMUSG00000032292.2 Nr2e3



Activity profile for motif Nr2e3.

activity profile for motif Nr2e3


Sorted Z-values histogram for motif Nr2e3

Sorted Z-values for motif Nr2e3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 161 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_141524379 16.596 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr18_-_35215008 15.532 ENSMUST00000091636.3
 Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr3_+_76074270 12.706 ENSMUST00000038364.8
 Fstl5
follistatin-like 5
chr12_+_88953399 9.171 ENSMUST00000057634.7
 Nrxn3
neurexin III
chr2_+_124610278 8.779 ENSMUST00000051419.8
ENSMUST00000077847.5
ENSMUST00000078621.5
ENSMUST00000076335.5
 Sema6d



sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D



chr1_+_19103022 7.819 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chrX_-_143933204 7.583 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr1_+_185454803 7.042 ENSMUST00000061093.6
 Slc30a10
solute carrier family 30, member 10
chr3_+_54156039 6.826 ENSMUST00000029311.6
 Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr5_+_19227046 6.577 ENSMUST00000088516.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_19907502 6.329 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_+_143640664 6.299 ENSMUST00000038252.2
 B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr18_-_22850738 6.162 ENSMUST00000092015.4
ENSMUST00000069215.6
 Nol4

nucleolar protein 4

chrX_+_166344692 6.110 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr16_-_52454074 6.044 ENSMUST00000023312.7
 Alcam
activated leukocyte cell adhesion molecule
chr5_+_19907774 6.021 ENSMUST00000115267.2
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_-_143933089 5.948 ENSMUST00000087313.3
 Dcx
doublecortin
chr10_+_90576570 5.928 ENSMUST00000182786.1
ENSMUST00000182600.1
 Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr10_-_109764840 5.527 ENSMUST00000163071.1
 Nav3
neuron navigator 3
chr2_-_45112890 5.495 ENSMUST00000076836.6
 Zeb2
zinc finger E-box binding homeobox 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 25.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
2.4 18.9 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
1.7 16.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.7 16.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.8 13.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 10.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.5 9.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.3 8.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 7.8 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.8 7.0 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.4 6.8 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 6.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.7 6.5 GO:0042447 hormone catabolic process(GO:0042447)
0.4 6.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.9 6.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 6.1 GO:0097320 membrane tubulation(GO:0097320)
0.1 6.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.9 5.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 4.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 4.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 47.3 GO:0045211 postsynaptic membrane(GO:0045211)
3.8 18.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 14.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 12.5 GO:0005874 microtubule(GO:0005874)
0.2 11.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 6.8 GO:0034704 calcium channel complex(GO:0034704)
0.1 6.5 GO:0005811 lipid particle(GO:0005811)
0.5 6.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.4 6.0 GO:0042101 T cell receptor complex(GO:0042101)
0.6 5.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.7 4.7 GO:0071437 invadopodium(GO:0071437)
0.0 4.5 GO:0005884 actin filament(GO:0005884)
0.1 4.3 GO:0045171 intercellular bridge(GO:0045171)
1.3 3.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 3.8 GO:0016324 apical plasma membrane(GO:0016324)
0.2 3.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 3.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 3.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 3.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 25.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 23.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
3.2 18.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.7 16.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
4.1 16.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.9 16.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 8.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 7.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.3 7.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 7.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 6.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 6.7 GO:0008017 microtubule binding(GO:0008017)
0.9 6.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.8 6.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.5 6.3 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 5.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 4.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 4.1 GO:0042805 actinin binding(GO:0042805)
0.3 3.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 3.4 GO:0031402 sodium ion binding(GO:0031402)