Motif ID: Nr2f2

Z-value: 0.693


Transcription factors associated with Nr2f2:

Gene SymbolEntrez IDGene Name
Nr2f2 ENSMUSG00000030551.7 Nr2f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f2mm10_v2_chr7_-_70360593_70360746-0.621.1e-04Click!


Activity profile for motif Nr2f2.

activity profile for motif Nr2f2


Sorted Z-values histogram for motif Nr2f2

Sorted Z-values for motif Nr2f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_92278155 2.605 ENSMUST00000159345.1
ENSMUST00000113102.3
 Naaa

N-acylethanolamine acid amidase

chr13_-_34652671 2.576 ENSMUST00000053459.7
 Pxdc1
PX domain containing 1
chr3_+_121723515 1.810 ENSMUST00000029771.8
 F3
coagulation factor III
chr17_-_12507704 1.786 ENSMUST00000024595.2
 Slc22a3
solute carrier family 22 (organic cation transporter), member 3
chr15_-_37791993 1.758 ENSMUST00000168992.1
ENSMUST00000148652.1
 Ncald

neurocalcin delta

chr1_+_9547948 1.642 ENSMUST00000144177.1
 Adhfe1
alcohol dehydrogenase, iron containing, 1
chr17_-_31277327 1.593 ENSMUST00000024832.7
 Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr10_-_9675163 1.559 ENSMUST00000100070.2
 Samd5
sterile alpha motif domain containing 5
chr2_-_170427828 1.448 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
 Bcas1


breast carcinoma amplified sequence 1


chr4_-_137766474 1.335 ENSMUST00000139951.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr14_+_118854695 1.273 ENSMUST00000100314.3
 Cldn10
claudin 10
chr15_-_78529617 1.265 ENSMUST00000023075.8
 C1qtnf6
C1q and tumor necrosis factor related protein 6
chr2_+_102658640 1.235 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr9_-_86695897 1.203 ENSMUST00000034989.8
 Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chrX_-_85776606 1.198 ENSMUST00000142152.1
ENSMUST00000156390.1
ENSMUST00000113978.2
 Gyk


glycerol kinase


chr13_-_29984219 1.184 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr12_+_81026800 1.145 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
 Smoc1


SPARC related modular calcium binding 1


chr3_+_54755574 1.134 ENSMUST00000029371.2
 Smad9
SMAD family member 9
chr18_+_67390700 1.134 ENSMUST00000001513.6
 Tubb6
tubulin, beta 6 class V
chr5_-_71658308 1.128 ENSMUST00000031121.5
 Gabra4
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.3 2.7 GO:0051608 histamine transport(GO:0051608)
0.5 2.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 2.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 2.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.6 1.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 1.8 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0 1.8 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.2 1.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.3 1.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 1.6 GO:0035082 axoneme assembly(GO:0035082)
0.0 1.6 GO:0006818 hydrogen transport(GO:0006818)
0.1 1.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 1.3 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 1.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 1.1 GO:2001023 regulation of response to drug(GO:2001023)
0.2 1.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 1.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.5 1.8 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2 1.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.1 1.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 0.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 0.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.2 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 106 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.1 2.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 2.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.4 2.0 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.6 1.9 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.6 1.8 GO:0048039 ubiquinone binding(GO:0048039)
0.6 1.8 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 1.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.6 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.0 1.5 GO:0008201 heparin binding(GO:0008201)
0.3 1.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.4 1.2 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.3 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 1.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)