Motif ID: Nr2f6

Z-value: 0.748


Transcription factors associated with Nr2f6:

Gene SymbolEntrez IDGene Name
Nr2f6 ENSMUSG00000002393.8 Nr2f6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f6mm10_v2_chr8_-_71381907_71381977-0.421.5e-02Click!


Activity profile for motif Nr2f6.

activity profile for motif Nr2f6


Sorted Z-values histogram for motif Nr2f6

Sorted Z-values for motif Nr2f6



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_137741601 2.897 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr1_-_138847579 2.689 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr4_+_85205417 2.038 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr15_+_89532816 1.898 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr17_-_35910032 1.847 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr4_+_85205120 1.795 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr9_+_108392820 1.763 ENSMUST00000035234.4
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr13_+_43370710 1.622 ENSMUST00000066804.4
Sirt5
sirtuin 5
chr10_-_79984227 1.547 ENSMUST00000052885.7
Tmem259
transmembrane protein 259
chr8_+_71469186 1.539 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
Dda1


DET1 and DDB1 associated 1


chr17_-_35909626 1.361 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr17_-_35132050 1.330 ENSMUST00000025249.6
Apom
apolipoprotein M
chr10_-_79983970 1.319 ENSMUST00000124536.1
Tmem259
transmembrane protein 259
chr7_+_64501687 1.247 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr16_-_4624984 1.239 ENSMUST00000014445.6
Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr7_+_30232310 1.208 ENSMUST00000108193.1
ENSMUST00000108192.1
Polr2i

polymerase (RNA) II (DNA directed) polypeptide I

chr7_-_30232186 1.198 ENSMUST00000006254.5
Tbcb
tubulin folding cofactor B
chr19_-_6921753 1.125 ENSMUST00000173635.1
Esrra
estrogen related receptor, alpha
chr10_+_43524080 1.096 ENSMUST00000057649.6
Gm9803
predicted gene 9803
chr11_+_101442440 1.026 ENSMUST00000107249.1
Rpl27
ribosomal protein L27
chr4_+_118409331 1.012 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr9_+_21002737 1.006 ENSMUST00000003386.5
Mrpl4
mitochondrial ribosomal protein L4
chr19_-_6921804 1.004 ENSMUST00000025906.4
Esrra
estrogen related receptor, alpha
chr10_-_22731918 0.939 ENSMUST00000095794.3
Tbpl1
TATA box binding protein-like 1
chr11_+_116198853 0.935 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr7_-_28766469 0.930 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr10_+_93589413 0.901 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr7_+_38183217 0.877 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chr15_-_27630644 0.869 ENSMUST00000059662.7
Fam105b
family with sequence similarity 105, member B
chr9_-_124424154 0.846 ENSMUST00000180270.1
Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr9_+_109051153 0.838 ENSMUST00000155541.1
ENSMUST00000120305.1
ENSMUST00000154113.1
ENSMUST00000128976.1
ENSMUST00000135942.1
ENSMUST00000143754.1
Shisa5





shisa homolog 5 (Xenopus laevis)





chr11_+_4986824 0.814 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr2_+_30266513 0.813 ENSMUST00000091132.6
Phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr12_-_93929102 0.806 ENSMUST00000180321.1
Gm9726
predicted gene 9726
chr4_+_97777606 0.805 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr9_-_21073494 0.794 ENSMUST00000010348.5
Fdx1l
ferredoxin 1-like
chr5_+_134176358 0.793 ENSMUST00000180674.1
B230377A18Rik
RIKEN cDNA B230377A18 gene
chr6_+_86365673 0.784 ENSMUST00000071492.7
Fam136a
family with sequence similarity 136, member A
chr13_-_73328442 0.774 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr19_+_10001669 0.756 ENSMUST00000121418.1
Rab3il1
RAB3A interacting protein (rabin3)-like 1
chr5_+_76840597 0.747 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr11_+_32283511 0.741 ENSMUST00000093209.3
Hba-a1
hemoglobin alpha, adult chain 1
chr11_+_101442298 0.683 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr10_-_93589621 0.679 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr2_+_30266721 0.668 ENSMUST00000113645.1
ENSMUST00000133877.1
ENSMUST00000139719.1
ENSMUST00000113643.1
ENSMUST00000150695.1
Phyhd1




phytanoyl-CoA dioxygenase domain containing 1




chr10_-_35711891 0.646 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chr6_+_113237843 0.639 ENSMUST00000113146.2
Mtmr14
myotubularin related protein 14
chr5_-_31202215 0.637 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
Zfp513


zinc finger protein 513


chr2_+_25242929 0.632 ENSMUST00000114355.1
ENSMUST00000060818.1
Rnf208

ring finger protein 208

chr5_-_24902315 0.623 ENSMUST00000131486.1
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr15_-_81871883 0.595 ENSMUST00000023117.8
Phf5a
PHD finger protein 5A
chr4_-_41697040 0.594 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr10_-_119240006 0.584 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chr7_+_45896941 0.575 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr4_+_97777780 0.572 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr10_+_128747850 0.553 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chr3_+_115888139 0.544 ENSMUST00000106505.1
ENSMUST00000043342.9
Dph5

DPH5 homolog (S. cerevisiae)

chr7_+_45897429 0.540 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr19_+_47228804 0.520 ENSMUST00000111807.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr4_-_11076160 0.510 ENSMUST00000058183.8
Ndufaf6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr5_+_36464998 0.510 ENSMUST00000031099.3
Grpel1
GrpE-like 1, mitochondrial
chr5_+_117120120 0.505 ENSMUST00000111978.1
Taok3
TAO kinase 3
chr4_-_137048695 0.504 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr6_-_83156393 0.502 ENSMUST00000153148.1
ENSMUST00000125894.1
Wdr54

WD repeat domain 54

chr11_+_115475645 0.500 ENSMUST00000035240.6
Armc7
armadillo repeat containing 7
chr2_+_25242227 0.476 ENSMUST00000154498.1
Rnf208
ring finger protein 208
chr2_+_164805082 0.467 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chr13_-_64248495 0.450 ENSMUST00000109769.2
Cdc14b
CDC14 cell division cycle 14B
chr3_+_138374121 0.444 ENSMUST00000171054.1
Adh6-ps1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr18_+_63708689 0.437 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr19_-_47536997 0.431 ENSMUST00000182808.1
ENSMUST00000049369.9
Obfc1

oligonucleotide/oligosaccharide-binding fold containing 1

chr7_-_89941196 0.420 ENSMUST00000117354.1
l7Rn6
lethal, Chr 7, Rinchik 6
chr3_+_95134088 0.410 ENSMUST00000066386.5
Lysmd1
LysM, putative peptidoglycan-binding, domain containing 1
chr19_-_3912711 0.407 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr9_+_108460518 0.397 ENSMUST00000061209.5
Ccdc71
coiled-coil domain containing 71
chr10_-_67548944 0.389 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr1_+_63176818 0.385 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr10_-_14705459 0.378 ENSMUST00000149485.1
ENSMUST00000154132.1
Vta1

Vps20-associated 1 homolog (S. cerevisiae)

chr9_-_22135675 0.378 ENSMUST00000165735.1
Acp5
acid phosphatase 5, tartrate resistant
chr3_+_4211716 0.374 ENSMUST00000170943.1
Gm8775
predicted gene 8775
chr16_+_18248961 0.374 ENSMUST00000100099.3
Trmt2a
TRM2 tRNA methyltransferase 2A
chr19_+_46152505 0.367 ENSMUST00000026254.7
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr15_-_100422991 0.357 ENSMUST00000138843.1
ENSMUST00000023774.5
Slc11a2

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

chr19_-_27429807 0.351 ENSMUST00000076219.4
D19Bwg1357e
DNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed
chr6_+_125145235 0.346 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr10_-_80102653 0.328 ENSMUST00000042771.7
Sbno2
strawberry notch homolog 2 (Drosophila)
chr7_-_89941084 0.319 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6

lethal, Chr 7, Rinchik 6

chr4_-_130174691 0.318 ENSMUST00000132545.2
ENSMUST00000175992.1
ENSMUST00000105999.2
Tinagl1


tubulointerstitial nephritis antigen-like 1


chr5_+_135187251 0.302 ENSMUST00000002825.5
Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr6_+_124712279 0.297 ENSMUST00000004375.9
Phb2
prohibitin 2
chr1_-_171360798 0.292 ENSMUST00000061878.4
Klhdc9
kelch domain containing 9
chr17_+_28691342 0.291 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
Mapk14



mitogen-activated protein kinase 14



chr4_-_117682233 0.285 ENSMUST00000102687.3
Dmap1
DNA methyltransferase 1-associated protein 1
chr3_-_95133989 0.281 ENSMUST00000172572.2
ENSMUST00000173462.2
Scnm1

sodium channel modifier 1

chr6_+_85431970 0.275 ENSMUST00000045693.7
Smyd5
SET and MYND domain containing 5
chr11_-_84870712 0.266 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
Ggnbp2



gametogenetin binding protein 2



chr16_+_18248866 0.264 ENSMUST00000115640.1
ENSMUST00000140206.1
Trmt2a

TRM2 tRNA methyltransferase 2A

chr16_-_18248697 0.258 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr17_-_23586214 0.257 ENSMUST00000115516.3
Zfp13
zinc finger protein 13
chr19_-_59943647 0.233 ENSMUST00000171986.1
Rab11fip2
RAB11 family interacting protein 2 (class I)
chr7_+_3617357 0.233 ENSMUST00000076657.4
ENSMUST00000108644.1
Ndufa3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3

chr13_-_59769751 0.230 ENSMUST00000057115.6
Isca1
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
chr15_-_95528702 0.227 ENSMUST00000166170.1
Nell2
NEL-like 2
chr11_-_84870812 0.226 ENSMUST00000168434.1
Ggnbp2
gametogenetin binding protein 2
chr8_+_117095854 0.224 ENSMUST00000034308.8
ENSMUST00000167370.1
ENSMUST00000176860.1
Bcmo1


beta-carotene 15,15'-monooxygenase


chr7_-_19715395 0.220 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr17_+_28691419 0.204 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr2_-_164804876 0.192 ENSMUST00000103094.4
ENSMUST00000017451.6
Acot8

acyl-CoA thioesterase 8

chr1_+_180726019 0.190 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chr7_-_98119482 0.185 ENSMUST00000138627.1
ENSMUST00000107127.1
ENSMUST00000107128.1
Myo7a


myosin VIIA


chr17_-_57247632 0.172 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr14_+_57798637 0.157 ENSMUST00000111267.1
Sap18
Sin3-associated polypeptide 18
chr17_+_47672720 0.138 ENSMUST00000152724.1
Usp49
ubiquitin specific peptidase 49
chr11_-_84870646 0.138 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2
chr12_-_55080098 0.136 ENSMUST00000021406.5
2700097O09Rik
RIKEN cDNA 2700097O09 gene
chr7_+_43444104 0.132 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr12_-_104751900 0.123 ENSMUST00000041987.6
Dicer1
dicer 1, ribonuclease type III
chr14_+_57798620 0.111 ENSMUST00000111268.1
Sap18
Sin3-associated polypeptide 18
chr19_-_44545836 0.105 ENSMUST00000111985.1
ENSMUST00000063632.7
Sec31b

Sec31 homolog B (S. cerevisiae)

chr15_-_76009440 0.081 ENSMUST00000170153.1
Fam83h
family with sequence similarity 83, member H
chr13_-_55571118 0.079 ENSMUST00000021957.6
Fam193b
family with sequence similarity 193, member B
chr9_+_118506226 0.065 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr19_-_45998479 0.063 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr9_+_108662098 0.062 ENSMUST00000035222.5
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr13_-_100492551 0.060 ENSMUST00000066984.7
ENSMUST00000066940.7
Gtf2h2

general transcription factor II H, polypeptide 2

chrX_+_6415736 0.059 ENSMUST00000143641.3
Shroom4
shroom family member 4
chrX_+_101449078 0.059 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr11_+_68968107 0.055 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chr3_+_121967822 0.053 ENSMUST00000137089.1
Arhgap29
Rho GTPase activating protein 29
chr5_-_134176720 0.048 ENSMUST00000076228.2
Wbscr16
Williams-Beuren syndrome chromosome region 16 homolog (human)
chr2_+_91082362 0.043 ENSMUST00000169852.1
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr1_+_74284930 0.043 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr13_-_92131494 0.038 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr19_-_21472552 0.037 ENSMUST00000087600.3
Gda
guanine deaminase
chr4_+_129461581 0.030 ENSMUST00000048162.8
ENSMUST00000138013.1
Bsdc1

BSD domain containing 1

chr11_-_118093702 0.023 ENSMUST00000018719.3
Dnah17
dynein, axonemal, heavy chain 17
chr4_+_110397764 0.021 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr12_+_55155104 0.012 ENSMUST00000110708.2
Srp54b
signal recognition particle 54B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 2.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 1.3 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.4 1.2 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.4 1.9 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 0.9 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.2 0.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 0.6 GO:0003360 brainstem development(GO:0003360)
0.2 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 2.9 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.2 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 0.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.5 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 3.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 1.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.6 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 0.3 GO:0071105 response to interleukin-11(GO:0071105) osteoclast fusion(GO:0072675)
0.1 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.5 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.4 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 1.4 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 2.1 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.3 GO:0060744 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 1.4 GO:0060074 synapse maturation(GO:0060074)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 2.9 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0048563 post-embryonic organ morphogenesis(GO:0048563) equilibrioception(GO:0050957)
0.0 0.0 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.8 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) dicarboxylic acid catabolic process(GO:0043649)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 1.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0097427 microtubule bundle(GO:0097427)
0.5 1.4 GO:1990879 CST complex(GO:1990879)
0.3 1.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 1.2 GO:0031314 mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 0.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.2 0.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.7 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 1.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.7 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.6 GO:0019808 polyamine binding(GO:0019808)
0.1 1.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 1.6 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.8 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.6 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.5 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.1 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 2.0 GO:0005496 steroid binding(GO:0005496)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.3 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 2.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)