Motif ID: Nr3c2

Z-value: 0.639


Transcription factors associated with Nr3c2:

Gene SymbolEntrez IDGene Name
Nr3c2 ENSMUSG00000031618.7 Nr3c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c2mm10_v2_chr8_+_76902277_76902476-0.411.9e-02Click!


Activity profile for motif Nr3c2.

activity profile for motif Nr3c2


Sorted Z-values histogram for motif Nr3c2

Sorted Z-values for motif Nr3c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr3c2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_95904683 3.877 ENSMUST00000147962.1
ENSMUST00000036181.8
 Car14

carbonic anhydrase 14

chr9_+_123366921 3.547 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr15_-_97020322 3.302 ENSMUST00000166223.1
 Slc38a4
solute carrier family 38, member 4
chr4_-_149137536 2.995 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
 Apitd1



apoptosis-inducing, TAF9-like domain 1



chr13_+_99100698 2.529 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr10_+_128225830 2.042 ENSMUST00000026455.7
 Mip
major intrinsic protein of eye lens fiber
chr5_-_31697598 1.967 ENSMUST00000031018.7
 Rbks
ribokinase
chr14_+_70530819 1.778 ENSMUST00000047331.6
 Lgi3
leucine-rich repeat LGI family, member 3
chr4_-_9643638 1.738 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr14_-_8309770 1.562 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr10_-_78464853 1.542 ENSMUST00000105385.1
 Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_-_171240055 1.400 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr10_-_78464969 1.335 ENSMUST00000041616.8
 Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr15_+_102102926 1.162 ENSMUST00000169627.1
ENSMUST00000046144.9
 Tenc1

tensin like C1 domain-containing phosphatase

chr2_+_172472512 0.959 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr10_-_117282262 0.879 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr1_-_74935549 0.795 ENSMUST00000094844.3
 Ccdc108
coiled-coil domain containing 108
chr8_+_94179089 0.750 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr10_+_26822560 0.595 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr6_-_69400097 0.495 ENSMUST00000177795.1
 Igkv4-62
immunoglobulin kappa variable 4-62
chr16_-_96192222 0.464 ENSMUST00000113804.1
ENSMUST00000054855.7
 Lca5l

Leber congenital amaurosis 5-like

chr11_+_101448403 0.453 ENSMUST00000010502.6
 Ifi35
interferon-induced protein 35
chr5_+_31697665 0.417 ENSMUST00000080598.7
 Bre
brain and reproductive organ-expressed protein
chr3_-_88739692 0.366 ENSMUST00000090946.2
 Gm10253
predicted gene 10253
chr10_+_21993890 0.336 ENSMUST00000092673.4
 Sgk1
serum/glucocorticoid regulated kinase 1
chr6_-_69631933 0.318 ENSMUST00000177697.1
 Igkv4-54
immunoglobulin kappa chain variable 4-54
chr2_-_91444622 0.301 ENSMUST00000064652.7
ENSMUST00000102594.4
ENSMUST00000094835.2
 1110051M20Rik


RIKEN cDNA 1110051M20 gene


chr15_-_82047579 0.250 ENSMUST00000166578.1
ENSMUST00000080622.7
 Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

chr6_-_6882068 0.211 ENSMUST00000142635.1
ENSMUST00000052609.8
 Dlx5

distal-less homeobox 5

chr8_+_71406003 0.210 ENSMUST00000119976.1
ENSMUST00000120725.1
 Ankle1

ankyrin repeat and LEM domain containing 1

chr14_+_66784523 0.061 ENSMUST00000071522.2
 Gm10032
predicted gene 10032

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0042822 vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.6 1.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.5 3.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 3.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.3 2.0 GO:0032782 cellular water homeostasis(GO:0009992) bile acid secretion(GO:0032782)
0.3 2.0 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.7 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.1 3.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 3.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.2 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 1.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 0.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.9 GO:0005921 gap junction(GO:0005921)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 1.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0031403 lithium ion binding(GO:0031403)
0.3 3.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 2.0 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.1 1.4 GO:0048038 quinone binding(GO:0048038)
0.1 3.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0034511 U4 snRNA binding(GO:0030621) U3 snoRNA binding(GO:0034511)
0.0 2.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 3.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)