Motif ID: Nr4a2

Z-value: 0.454


Transcription factors associated with Nr4a2:

Gene SymbolEntrez IDGene Name
Nr4a2 ENSMUSG00000026826.7 Nr4a2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a2mm10_v2_chr2_-_57124003_571240710.144.5e-01Click!


Activity profile for motif Nr4a2.

activity profile for motif Nr4a2


Sorted Z-values histogram for motif Nr4a2

Sorted Z-values for motif Nr4a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr4a2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 96 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 1.539 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr8_+_68880491 1.226 ENSMUST00000015712.8
 Lpl
lipoprotein lipase
chr11_+_70657687 1.077 ENSMUST00000134087.1
ENSMUST00000170716.1
 Eno3

enolase 3, beta muscle

chr11_+_70657196 0.933 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
 Eno3



enolase 3, beta muscle



chrX_+_150589907 0.810 ENSMUST00000080884.4
 Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_+_111581422 0.794 ENSMUST00000064930.3
 C130026L21Rik
RIKEN cDNA C130026L21 gene
chr6_-_124814288 0.787 ENSMUST00000172132.2
 Tpi1
triosephosphate isomerase 1
chr10_-_40302186 0.769 ENSMUST00000099945.4
 Amd1
S-adenosylmethionine decarboxylase 1
chr9_-_32344237 0.663 ENSMUST00000034533.5
 Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chrX_-_48513518 0.640 ENSMUST00000114945.2
ENSMUST00000037349.7
 Aifm1

apoptosis-inducing factor, mitochondrion-associated 1

chr13_+_94875600 0.607 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr17_+_29360923 0.591 ENSMUST00000024810.6
 Fgd2
FYVE, RhoGEF and PH domain containing 2
chr2_+_4976113 0.562 ENSMUST00000167607.1
ENSMUST00000115010.2
 Ucma

upper zone of growth plate and cartilage matrix associated

chr10_-_35711891 0.542 ENSMUST00000080898.2
 Amd2
S-adenosylmethionine decarboxylase 2
chr5_-_121527186 0.528 ENSMUST00000152270.1
 Mapkapk5
MAP kinase-activated protein kinase 5
chr18_+_86711059 0.501 ENSMUST00000068423.3
 Cbln2
cerebellin 2 precursor protein
chr11_-_52282564 0.500 ENSMUST00000086844.3
 Tcf7
transcription factor 7, T cell specific
chr13_+_93304066 0.491 ENSMUST00000109493.1
 Homer1
homer homolog 1 (Drosophila)
chr13_-_97747373 0.485 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chrX_-_73921917 0.466 ENSMUST00000114389.3
 Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.4 1.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.3 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.3 1.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 0.8 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.1 0.6 GO:1903624 regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.0 0.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.5 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.4 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.1 0.3 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.1 0.3 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.1 0.3 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.3 GO:0031415 NatA complex(GO:0031415)
0.2 1.2 GO:0042627 chylomicron(GO:0042627)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 0.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.3 GO:0019808 polyamine binding(GO:0019808)
0.3 1.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.2 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)