Motif ID: Nr4a3

Z-value: 0.377


Transcription factors associated with Nr4a3:

Gene SymbolEntrez IDGene Name
Nr4a3 ENSMUSG00000028341.3 Nr4a3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a3mm10_v2_chr4_+_48045144_480451600.183.1e-01Click!


Activity profile for motif Nr4a3.

activity profile for motif Nr4a3


Sorted Z-values histogram for motif Nr4a3

Sorted Z-values for motif Nr4a3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr4a3

PNG image of the network

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Top targets:


Showing 1 to 20 of 96 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1245685 0.850 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr19_-_4334001 0.707 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr16_+_10545390 0.642 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr15_+_25773985 0.577 ENSMUST00000125667.1
Myo10
myosin X
chrY_-_1245753 0.575 ENSMUST00000154004.1
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr5_+_66968559 0.498 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr16_-_4523056 0.466 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr4_+_43578921 0.387 ENSMUST00000030190.8
Rgp1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr15_-_76918010 0.372 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chr15_+_100761741 0.370 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr17_-_35909626 0.328 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr18_-_60624304 0.319 ENSMUST00000097566.3
Synpo
synaptopodin
chr2_-_163417092 0.318 ENSMUST00000127038.1
Oser1
oxidative stress responsive serine rich 1
chr19_+_46152505 0.315 ENSMUST00000026254.7
Gbf1
golgi-specific brefeldin A-resistance factor 1
chrX_+_73675500 0.310 ENSMUST00000171398.1
Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr7_+_102267795 0.301 ENSMUST00000033289.4
Stim1
stromal interaction molecule 1
chr4_-_126202583 0.289 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr2_-_33468493 0.252 ENSMUST00000113156.1
ENSMUST00000028125.5
ENSMUST00000126442.1
Zbtb43


zinc finger and BTB domain containing 43


chr11_+_70657687 0.235 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr19_-_45998479 0.231 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.8 GO:1901524 regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.1 0.7 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 0.5 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.3 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0036376 sodium ion export from cell(GO:0036376)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0086017 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) Purkinje myocyte action potential(GO:0086017) membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.2 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)