Motif ID: Nr5a2

Z-value: 0.774


Transcription factors associated with Nr5a2:

Gene SymbolEntrez IDGene Name
Nr5a2 ENSMUSG00000026398.8 Nr5a2



Activity profile for motif Nr5a2.

activity profile for motif Nr5a2


Sorted Z-values histogram for motif Nr5a2

Sorted Z-values for motif Nr5a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr5a2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_21787218 6.250 ENSMUST00000091751.2
 Hist1h2an
histone cluster 1, H2an
chr13_-_21753851 4.110 ENSMUST00000074752.2
 Hist1h2ak
histone cluster 1, H2ak
chr7_-_46179929 3.795 ENSMUST00000033123.6
 Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr8_+_124793013 3.384 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr13_-_22042949 3.218 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr4_-_82505274 3.194 ENSMUST00000050872.8
ENSMUST00000064770.2
 Nfib

nuclear factor I/B

chr8_+_124793061 3.142 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr18_+_45268876 3.047 ENSMUST00000183850.1
ENSMUST00000066890.7
 Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr11_+_58948890 2.965 ENSMUST00000078267.3
 Hist3h2ba
histone cluster 3, H2ba
chr12_+_102554966 2.918 ENSMUST00000021610.5
 Chga
chromogranin A
chr2_+_178119166 2.906 ENSMUST00000108916.1
 Phactr3
phosphatase and actin regulator 3
chr4_-_82505749 2.865 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr11_+_98741805 2.795 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr1_+_136131382 2.785 ENSMUST00000075164.4
 Kif21b
kinesin family member 21B
chr18_+_77185815 2.717 ENSMUST00000079618.4
 St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr2_+_178118975 2.676 ENSMUST00000108917.1
 Phactr3
phosphatase and actin regulator 3
chr10_+_80264942 2.614 ENSMUST00000105362.1
ENSMUST00000105361.3
 Dazap1

DAZ associated protein 1

chr4_+_13751297 2.594 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_32588192 2.580 ENSMUST00000115096.2
 Plxna4
plexin A4
chr19_-_46327121 2.534 ENSMUST00000041391.4
ENSMUST00000096029.5
 Psd

pleckstrin and Sec7 domain containing


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 17.4 GO:0006342 chromatin silencing(GO:0006342)
2.1 8.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 7.1 GO:0006334 nucleosome assembly(GO:0006334)
0.3 6.5 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
1.5 4.6 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.0 4.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.7 3.5 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 3.5 GO:0010043 response to zinc ion(GO:0010043)
0.0 3.0 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
1.0 2.9 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.1 2.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.9 2.8 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 2.7 GO:0007018 microtubule-based movement(GO:0007018)
0.6 2.6 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.0 2.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 2.6 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 2.5 GO:0051017 actin filament bundle assembly(GO:0051017)
0.5 2.4 GO:0030242 pexophagy(GO:0030242)
0.0 2.3 GO:0032091 negative regulation of protein binding(GO:0032091)
0.4 2.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.4 GO:0000790 nuclear chromatin(GO:0000790)
0.4 8.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 6.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.6 GO:0000786 nucleosome(GO:0000786)
0.4 4.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 3.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 3.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 3.0 GO:0005604 basement membrane(GO:0005604)
0.6 2.9 GO:0042583 chromaffin granule(GO:0042583)
0.0 2.8 GO:0005871 kinesin complex(GO:0005871)
0.2 2.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 2.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.9 GO:0005844 polysome(GO:0005844)
0.2 1.7 GO:0001520 outer dense fiber(GO:0001520)
0.0 1.7 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.2 1.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.6 GO:0005721 pericentric heterochromatin(GO:0005721)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.5 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 6.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 4.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 4.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.8 GO:0019905 syntaxin binding(GO:0019905)
0.1 3.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.8 3.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 3.0 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.9 2.8 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.5 2.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 2.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.6 2.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 2.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 2.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.5 2.0 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.3 1.6 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)