Motif ID: Olig2_Olig3
Z-value: 1.017
Transcription factors associated with Olig2_Olig3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Olig2 | ENSMUSG00000039830.8 | Olig2 |
| Olig3 | ENSMUSG00000045591.5 | Olig3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Olig2 | mm10_v2_chr16_+_91225550_91225579 | -0.44 | 1.1e-02 | Click! |
| Olig3 | mm10_v2_chr10_+_19356558_19356565 | 0.22 | 2.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 6.8 | GO:0002159 | desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) |
| 2.1 | 10.5 | GO:0015671 | oxygen transport(GO:0015671) |
| 1.8 | 10.8 | GO:0032796 | uropod organization(GO:0032796) |
| 1.4 | 5.6 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 1.1 | 4.4 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 1.1 | 6.5 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 1.0 | 5.0 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.9 | 3.7 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
| 0.9 | 2.6 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.7 | 2.1 | GO:0048211 | Golgi vesicle docking(GO:0048211) |
| 0.6 | 1.9 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.6 | 1.7 | GO:0010911 | regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) |
| 0.5 | 2.7 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.5 | 1.6 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.5 | 2.0 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
| 0.5 | 4.8 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.5 | 1.4 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.4 | 1.3 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.4 | 1.3 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
| 0.4 | 4.3 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.4 | 3.8 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.4 | 1.7 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
| 0.4 | 1.2 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 0.4 | 1.5 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
| 0.4 | 2.3 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.4 | 1.5 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
| 0.4 | 4.7 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.3 | 7.1 | GO:0014823 | response to activity(GO:0014823) |
| 0.3 | 1.6 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.3 | 0.9 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 0.3 | 0.9 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
| 0.3 | 0.9 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) |
| 0.3 | 1.4 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.3 | 1.5 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.2 | 1.0 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.2 | 1.2 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.2 | 1.0 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
| 0.2 | 0.7 | GO:0032829 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of transforming growth factor beta1 production(GO:0032914) negative regulation of interleukin-2 biosynthetic process(GO:0045085) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.2 | 5.7 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 0.2 | 1.6 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.2 | 0.9 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
| 0.2 | 2.1 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.2 | 1.6 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.2 | 3.6 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.2 | 1.6 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.2 | 0.6 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) |
| 0.2 | 0.8 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.2 | 0.8 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.2 | 0.9 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
| 0.2 | 0.5 | GO:0051030 | snRNA transport(GO:0051030) |
| 0.2 | 0.5 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402) |
| 0.2 | 1.6 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
| 0.2 | 3.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.2 | 0.3 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.2 | 0.8 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.2 | 1.4 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.2 | 1.2 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.1 | 1.0 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.1 | 2.5 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.1 | 0.4 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 0.1 | 2.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.4 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.1 | 0.1 | GO:0072070 | loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236) |
| 0.1 | 0.8 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
| 0.1 | 4.7 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
| 0.1 | 0.6 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
| 0.1 | 1.8 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 1.8 | GO:0050667 | homocysteine metabolic process(GO:0050667) |
| 0.1 | 1.7 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.1 | 0.7 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
| 0.1 | 1.6 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.1 | 8.5 | GO:0032526 | response to retinoic acid(GO:0032526) |
| 0.1 | 3.0 | GO:0034724 | DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724) |
| 0.1 | 0.4 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.1 | 2.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 0.6 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.1 | 0.4 | GO:0043416 | regulation of skeletal muscle tissue regeneration(GO:0043416) |
| 0.1 | 0.4 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.1 | 0.5 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 0.1 | 1.2 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 0.8 | GO:2000193 | positive regulation of fatty acid transport(GO:2000193) |
| 0.1 | 5.2 | GO:0007405 | neuroblast proliferation(GO:0007405) |
| 0.1 | 1.8 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.1 | 0.6 | GO:0048385 | regulation of retinoic acid receptor signaling pathway(GO:0048385) |
| 0.1 | 0.3 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.1 | 0.4 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.1 | 5.5 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
| 0.1 | 0.7 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 0.1 | 0.3 | GO:0090164 | protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164) |
| 0.1 | 0.6 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 1.9 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.1 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 2.9 | GO:0002066 | columnar/cuboidal epithelial cell development(GO:0002066) |
| 0.1 | 0.3 | GO:1904690 | adenosine to inosine editing(GO:0006382) regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.1 | 0.4 | GO:0000022 | mitotic spindle elongation(GO:0000022) spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256) |
| 0.1 | 0.4 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 1.1 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 1.0 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 0.3 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.1 | 1.2 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.1 | 1.5 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.1 | 0.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.0 | 0.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.0 | 0.3 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.0 | 0.5 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.8 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 1.7 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.0 | 0.9 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.0 | 0.2 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.0 | 0.8 | GO:0016556 | mRNA modification(GO:0016556) |
| 0.0 | 0.8 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.0 | 1.2 | GO:0060135 | maternal process involved in female pregnancy(GO:0060135) |
| 0.0 | 4.0 | GO:0048015 | phosphatidylinositol-mediated signaling(GO:0048015) |
| 0.0 | 0.5 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.0 | 0.9 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
| 0.0 | 0.4 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.0 | 1.1 | GO:0016445 | somatic diversification of immunoglobulins(GO:0016445) |
| 0.0 | 0.3 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
| 0.0 | 0.1 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
| 0.0 | 0.4 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.0 | 0.5 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.8 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 0.3 | GO:1903894 | regulation of IRE1-mediated unfolded protein response(GO:1903894) |
| 0.0 | 0.2 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 0.0 | 1.3 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.0 | 0.4 | GO:0035384 | thioester biosynthetic process(GO:0035384) acyl-CoA biosynthetic process(GO:0071616) |
| 0.0 | 1.2 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.3 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 0.2 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 1.9 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.0 | 0.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.0 | 1.0 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.2 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.0 | 0.1 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.0 | 0.1 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 0.0 | 1.6 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 0.9 | GO:0050868 | negative regulation of T cell activation(GO:0050868) |
| 0.0 | 1.6 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 1.0 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.0 | 0.3 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.1 | GO:0006517 | protein deglycosylation(GO:0006517) |
| 0.0 | 0.9 | GO:0090305 | nucleic acid phosphodiester bond hydrolysis(GO:0090305) |
| 0.0 | 0.2 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 0.4 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.0 | 0.1 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.0 | 0.8 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 6.9 | GO:0044299 | C-fiber(GO:0044299) |
| 1.4 | 8.6 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 1.3 | 10.5 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.7 | 8.0 | GO:0030057 | desmosome(GO:0030057) |
| 0.6 | 6.5 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.5 | 1.5 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.5 | 1.5 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.5 | 5.2 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.5 | 1.4 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.5 | 4.1 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.5 | 0.9 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.4 | 10.8 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.4 | 2.1 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.3 | 1.7 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.3 | 3.3 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.3 | 2.3 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.3 | 1.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.3 | 3.2 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.3 | 1.7 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.3 | 0.8 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.3 | 0.8 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.3 | 1.6 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.3 | 0.8 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.2 | 1.0 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.2 | 1.0 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.2 | 1.3 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.2 | 1.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.2 | 1.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.2 | 1.6 | GO:0071664 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
| 0.2 | 1.8 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.2 | 1.0 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.2 | 1.1 | GO:0030677 | nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) |
| 0.1 | 1.9 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 7.8 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 1.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.1 | 0.8 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 0.9 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.1 | 0.4 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.1 | 0.7 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.1 | 1.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.3 | GO:0031417 | NatC complex(GO:0031417) |
| 0.1 | 2.5 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.1 | 3.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 0.7 | GO:0005775 | vacuolar lumen(GO:0005775) |
| 0.1 | 1.1 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.1 | 0.4 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.1 | 7.0 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 1.0 | GO:0031105 | septin complex(GO:0031105) |
| 0.1 | 3.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 0.7 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 1.4 | GO:0030894 | replisome(GO:0030894) |
| 0.1 | 0.5 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 0.1 | 0.8 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 0.4 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.1 | 0.9 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 3.0 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.5 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.7 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 2.0 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.0 | 0.3 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.5 | GO:0043073 | germ cell nucleus(GO:0043073) |
| 0.0 | 1.6 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 3.6 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.4 | GO:0044453 | nuclear membrane part(GO:0044453) |
| 0.0 | 0.7 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.0 | 0.9 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.4 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 3.0 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 1.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.8 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 0.1 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.0 | 0.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.4 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 10.6 | GO:0070161 | adherens junction(GO:0005912) anchoring junction(GO:0070161) |
| 0.0 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.0 | 0.7 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 1.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.1 | GO:1990879 | CST complex(GO:1990879) |
| 0.0 | 0.4 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 1.9 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.6 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.3 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 0.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 1.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.8 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 1.2 | GO:0000793 | condensed chromosome(GO:0000793) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 10.5 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 1.3 | 9.1 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 1.2 | 3.7 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
| 1.1 | 5.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 1.1 | 10.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 1.0 | 3.9 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.9 | 2.6 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.7 | 4.4 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.7 | 4.1 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.7 | 2.7 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.6 | 6.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.5 | 2.1 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 0.5 | 1.6 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.5 | 1.5 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139) |
| 0.5 | 3.6 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.5 | 5.0 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.5 | 6.5 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.5 | 1.5 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 0.5 | 1.8 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.4 | 6.5 | GO:0015106 | bicarbonate transmembrane transporter activity(GO:0015106) |
| 0.4 | 1.1 | GO:0051870 | methotrexate binding(GO:0051870) |
| 0.4 | 1.5 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.4 | 1.9 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.3 | 4.5 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.3 | 0.9 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.3 | 0.9 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 0.3 | 4.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.3 | 0.9 | GO:0043532 | angiostatin binding(GO:0043532) |
| 0.3 | 1.7 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.3 | 0.8 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
| 0.2 | 1.5 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.2 | 1.0 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 0.2 | 1.2 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.2 | 2.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.2 | 2.4 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.2 | 4.1 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.2 | 1.9 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.2 | 1.0 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.2 | 0.8 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.2 | 1.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.2 | 1.7 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.2 | 1.0 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
| 0.2 | 2.1 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.2 | 1.0 | GO:0052630 | CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630) |
| 0.1 | 0.9 | GO:0002135 | CTP binding(GO:0002135) |
| 0.1 | 1.5 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 0.4 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.1 | 1.1 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 0.4 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
| 0.1 | 1.2 | GO:0005167 | neurotrophin TRK receptor binding(GO:0005167) |
| 0.1 | 0.7 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 0.3 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
| 0.1 | 2.3 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
| 0.1 | 1.0 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
| 0.1 | 1.6 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 1.3 | GO:0070636 | purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701) single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.1 | 1.1 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 1.6 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 0.9 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 1.7 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 0.2 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.1 | 0.4 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 0.9 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 1.6 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.1 | 1.7 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 1.0 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 1.6 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 0.5 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.1 | 1.3 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 0.4 | GO:0035381 | purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381) purinergic receptor activity(GO:0035586) |
| 0.1 | 0.3 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.1 | 1.2 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 2.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 0.3 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.1 | 0.7 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.1 | 2.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 0.6 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.1 | 0.5 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) |
| 0.1 | 3.5 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.1 | 2.7 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 0.3 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.0 | 0.7 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 2.3 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
| 0.0 | 0.4 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.0 | 10.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.5 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 1.6 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.2 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.0 | 2.1 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 1.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.2 | GO:0034916 | 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760) |
| 0.0 | 0.2 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.4 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.3 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
| 0.0 | 0.1 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.1 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.0 | 0.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.0 | 0.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.2 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.0 | 0.8 | GO:0004521 | endoribonuclease activity(GO:0004521) |
| 0.0 | 0.8 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.7 | GO:0017069 | snRNA binding(GO:0017069) |
| 0.0 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.0 | 2.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 3.9 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 1.9 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 0.7 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.0 | 1.4 | GO:0004872 | receptor activity(GO:0004872) molecular transducer activity(GO:0060089) |
| 0.0 | 3.9 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.4 | GO:0000976 | transcription regulatory region sequence-specific DNA binding(GO:0000976) |
| 0.0 | 0.8 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 1.2 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 0.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.1 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
| 0.0 | 0.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
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