Motif ID: Onecut2_Onecut3

Z-value: 0.561

Transcription factors associated with Onecut2_Onecut3:

Gene SymbolEntrez IDGene Name
Onecut2 ENSMUSG00000045991.12 Onecut2
Onecut3 ENSMUSG00000045518.8 Onecut3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Onecut3mm10_v2_chr10_+_80494835_80494873-0.125.2e-01Click!
Onecut2mm10_v2_chr18_+_64340225_64340364-0.077.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Onecut2_Onecut3

PNG image of the network

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Top targets:


Showing 1 to 20 of 191 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 4.751 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_49636847 2.553 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr12_+_109544498 2.177 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr3_+_102010138 1.737 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chrY_+_897782 1.698 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr12_+_109545390 1.664 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr6_+_5390387 1.365 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr10_-_45470201 1.319 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr17_+_24720063 1.147 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
Rps2


ribosomal protein S2


chr6_-_127769427 1.066 ENSMUST00000032500.8
Prmt8
protein arginine N-methyltransferase 8
chr7_-_142661858 0.949 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr16_-_23890805 0.940 ENSMUST00000004480.3
Sst
somatostatin
chr19_+_60144682 0.882 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr10_+_69533761 0.804 ENSMUST00000182884.1
Ank3
ankyrin 3, epithelial
chr9_+_55326913 0.801 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078

expressed sequence AI118078

chr3_+_130068390 0.783 ENSMUST00000076703.6
Gm9396
predicted gene 9396
chr10_-_61979073 0.769 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr5_-_129623655 0.739 ENSMUST00000076842.5
Gm6139
predicted gene 6139
chr18_-_61259987 0.666 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr7_-_34655500 0.645 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 3.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 2.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 2.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.7 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 1.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.3 1.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.7 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.6 GO:0097421 liver regeneration(GO:0097421)
0.2 0.5 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.2 0.5 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 0.5 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 0.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.4 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)