Motif ID: Pax2

Z-value: 0.814


Transcription factors associated with Pax2:

Gene SymbolEntrez IDGene Name
Pax2 ENSMUSG00000004231.9 Pax2



Activity profile for motif Pax2.

activity profile for motif Pax2


Sorted Z-values histogram for motif Pax2

Sorted Z-values for motif Pax2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_57008187 4.777 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr18_+_34861200 4.368 ENSMUST00000165033.1
 Egr1
early growth response 1
chrX_+_166344692 4.239 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr17_+_26715644 3.973 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
 Crebrf



CREB3 regulatory factor



chr16_-_45158566 3.295 ENSMUST00000181177.1
 Slc35a5
solute carrier family 35, member A5
chr16_-_45158624 3.285 ENSMUST00000180636.1
 Slc35a5
solute carrier family 35, member A5
chr7_+_44850393 3.137 ENSMUST00000136232.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr16_-_45158650 3.050 ENSMUST00000023344.3
 Slc35a5
solute carrier family 35, member A5
chr16_-_45158183 3.015 ENSMUST00000114600.1
 Slc35a5
solute carrier family 35, member A5
chr16_-_45158453 2.859 ENSMUST00000181750.1
 Slc35a5
solute carrier family 35, member A5
chr11_+_35769462 2.816 ENSMUST00000018990.7
 Pank3
pantothenate kinase 3
chr12_-_84450944 2.753 ENSMUST00000085192.5
 Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr10_+_111164794 2.543 ENSMUST00000105275.1
ENSMUST00000095310.1
 Osbpl8

oxysterol binding protein-like 8

chr14_-_18239053 2.504 ENSMUST00000090543.5
 Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr4_-_148038769 2.110 ENSMUST00000030879.5
ENSMUST00000137724.1
 Clcn6

chloride channel 6

chr9_+_64811313 2.105 ENSMUST00000038890.5
 Dennd4a
DENN/MADD domain containing 4A
chr9_-_42124276 2.051 ENSMUST00000060989.8
 Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr13_+_13590402 2.038 ENSMUST00000110559.1
 Lyst
lysosomal trafficking regulator
chr17_-_66077022 1.869 ENSMUST00000150766.1
ENSMUST00000038116.5
 Ankrd12

ankyrin repeat domain 12

chrX_+_68678541 1.766 ENSMUST00000088546.5
 Fmr1
fragile X mental retardation syndrome 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.6 GO:0008643 carbohydrate transport(GO:0008643)
1.7 5.2 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.2 4.8 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.3 4.6 GO:0045792 negative regulation of cell size(GO:0045792)
1.5 4.4 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.6 4.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.8 4.0 GO:1900170 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
1.3 3.8 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.9 2.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 2.8 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.6 2.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.2 2.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.5 2.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.5 2.1 GO:2001137 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137)
0.2 2.1 GO:0060746 parental behavior(GO:0060746)
0.2 2.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 2.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.7 2.0 GO:0033364 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.4 2.0 GO:0042117 monocyte activation(GO:0042117)
0.4 2.0 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 18.6 GO:0000139 Golgi membrane(GO:0000139)
1.7 5.2 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.4 4.6 GO:0031931 TORC1 complex(GO:0031931)
0.3 3.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.8 GO:0090544 BAF-type complex(GO:0090544)
0.5 2.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 2.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 2.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 1.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) mitotic spindle midzone(GO:1990023)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 1.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 16.9 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.4 4.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 4.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.9 4.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 4.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.6 2.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 2.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.4 2.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 2.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.5 2.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 2.3 GO:0042169 SH2 domain binding(GO:0042169)
0.2 2.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 2.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 2.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.7 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.2 1.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.6 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.4 1.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)