Motif ID: Pax3

Z-value: 0.513


Transcription factors associated with Pax3:

Gene SymbolEntrez IDGene Name
Pax3 ENSMUSG00000004872.9 Pax3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax3mm10_v2_chr1_-_78197112_78197134-0.373.2e-02Click!


Activity profile for motif Pax3.

activity profile for motif Pax3


Sorted Z-values histogram for motif Pax3

Sorted Z-values for motif Pax3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_127077374 2.078 ENSMUST00000046751.6
ENSMUST00000094713.3
Zmym6

zinc finger, MYM-type 6

chr9_-_40346290 2.070 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr10_+_82138253 1.711 ENSMUST00000105314.2
AU041133
expressed sequence AU041133
chr2_-_136387929 1.637 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr19_-_36736653 1.391 ENSMUST00000087321.2
Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr14_+_51893610 1.321 ENSMUST00000047726.5
ENSMUST00000161888.1
Slc39a2

solute carrier family 39 (zinc transporter), member 2

chrX_-_103623648 1.273 ENSMUST00000156211.1
Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr10_-_70592782 1.262 ENSMUST00000162251.1
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chrX_+_159840463 1.232 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr13_+_21716385 1.219 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr7_+_30121915 1.154 ENSMUST00000098596.3
ENSMUST00000153792.1
Zfp382

zinc finger protein 382

chr8_+_71887264 1.150 ENSMUST00000034259.7
Zfp709
zinc finger protein 709
chr2_+_168230597 1.128 ENSMUST00000099071.3
Mocs3
molybdenum cofactor synthesis 3
chr12_+_52699297 1.118 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr18_+_35562158 0.894 ENSMUST00000166793.1
Matr3
matrin 3
chr12_+_38780284 0.883 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr7_+_120843551 0.828 ENSMUST00000106489.1
ENSMUST00000143279.1
Eef2k

eukaryotic elongation factor-2 kinase

chr12_+_38780817 0.828 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr12_+_38781093 0.727 ENSMUST00000161513.1
Etv1
ets variant gene 1
chrX_-_103623704 0.708 ENSMUST00000130063.1
ENSMUST00000125419.1
Ftx

Ftx transcript, Xist regulator (non-protein coding)

chr2_+_102659213 0.701 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr8_-_71043040 0.695 ENSMUST00000170101.1
Gm17576
predicted gene, 17576
chr1_+_176814660 0.680 ENSMUST00000056773.8
ENSMUST00000027785.8
Sdccag8

serologically defined colon cancer antigen 8

chr3_+_36159522 0.599 ENSMUST00000165956.2
D3Ertd254e
DNA segment, Chr 3, ERATO Doi 254, expressed
chr11_-_58323113 0.597 ENSMUST00000108829.1
Zfp672
zinc finger protein 672
chr16_-_88056176 0.596 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
Grik1


glutamate receptor, ionotropic, kainate 1


chr16_+_32877775 0.498 ENSMUST00000023489.4
ENSMUST00000171325.1
Fyttd1

forty-two-three domain containing 1

chr17_+_21691860 0.484 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr3_+_79884496 0.463 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr16_-_32877723 0.409 ENSMUST00000119810.1
1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr17_+_87107621 0.354 ENSMUST00000041369.6
Socs5
suppressor of cytokine signaling 5
chr8_+_33428709 0.263 ENSMUST00000059351.7
5930422O12Rik
RIKEN cDNA 5930422O12 gene
chr3_+_108186332 0.237 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
Amigo1



adhesion molecule with Ig like domain 1



chr4_-_25281801 0.176 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr11_+_70970467 0.086 ENSMUST00000178822.1
ENSMUST00000108529.3
ENSMUST00000169965.1
ENSMUST00000167509.1
Rpain



RPA interacting protein



chr13_-_21716143 0.004 ENSMUST00000091756.1
Hist1h2bl
histone cluster 1, H2bl

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.3 1.1 GO:0018307 enzyme active site formation(GO:0018307)
0.3 1.1 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.6 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1 2.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.4 GO:0071638 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 1.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 1.6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.9 GO:0003281 ventricular septum development(GO:0003281)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0042587 glycogen granule(GO:0042587)
0.1 0.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.7 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.2 1.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.2 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.1 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)