Motif ID: Pax5

Z-value: 1.529


Transcription factors associated with Pax5:

Gene SymbolEntrez IDGene Name
Pax5 ENSMUSG00000014030.9 Pax5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5mm10_v2_chr4_-_44710408_44710418-0.309.3e-02Click!


Activity profile for motif Pax5.

activity profile for motif Pax5


Sorted Z-values histogram for motif Pax5

Sorted Z-values for motif Pax5



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_79386943 11.761 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr16_+_45094036 9.711 ENSMUST00000061050.5
 Ccdc80
coiled-coil domain containing 80
chr16_+_45093611 9.497 ENSMUST00000099498.2
 Ccdc80
coiled-coil domain containing 80
chr3_-_152982240 9.409 ENSMUST00000044278.5
 St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr11_-_102897123 9.406 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr1_-_172297989 9.282 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
 Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr4_-_64046925 8.547 ENSMUST00000107377.3
 Tnc
tenascin C
chr9_+_37367354 7.793 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr15_-_79164477 7.529 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr11_-_102897146 6.954 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr5_+_89027959 6.707 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr14_+_54936456 6.693 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr3_+_89520152 6.548 ENSMUST00000000811.7
 Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr19_-_57008187 6.503 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr11_+_78324200 6.067 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr12_+_16653470 5.923 ENSMUST00000111064.1
 Ntsr2
neurotensin receptor 2
chr10_+_127725392 5.877 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr7_-_79149042 5.795 ENSMUST00000032825.8
ENSMUST00000107409.3
 Mfge8

milk fat globule-EGF factor 8 protein

chr6_-_18514802 5.768 ENSMUST00000090601.5
 Cttnbp2
cortactin binding protein 2
chr16_-_36784784 5.672 ENSMUST00000165531.1
 Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 352 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 16.5 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.7 14.9 GO:0015701 bicarbonate transport(GO:0015701)
1.1 13.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 12.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.4 11.2 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.8 10.4 GO:0070842 aggresome assembly(GO:0070842)
3.1 9.3 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.6 8.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
2.8 8.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.8 8.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 8.5 GO:0006813 potassium ion transport(GO:0006813)
0.6 7.5 GO:0048484 enteric nervous system development(GO:0048484)
0.1 7.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 7.0 GO:0007601 visual perception(GO:0007601)
0.0 6.5 GO:0008360 regulation of cell shape(GO:0008360)
0.6 6.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 6.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
1.0 5.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.5 5.8 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 5.8 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 142 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 56.4 GO:0045211 postsynaptic membrane(GO:0045211)
1.7 27.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 18.5 GO:0005887 integral component of plasma membrane(GO:0005887)
4.1 16.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 15.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 12.7 GO:0005901 caveola(GO:0005901)
0.2 10.1 GO:0031594 neuromuscular junction(GO:0031594)
1.3 9.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 8.8 GO:0005581 collagen trimer(GO:0005581)
0.0 8.1 GO:0030027 lamellipodium(GO:0030027)
0.8 6.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 6.1 GO:0043204 perikaryon(GO:0043204)
0.1 5.7 GO:0005871 kinesin complex(GO:0005871)
0.0 5.3 GO:0030424 axon(GO:0030424)
0.0 4.6 GO:0060076 excitatory synapse(GO:0060076)
1.5 4.5 GO:0071953 elastic fiber(GO:0071953)
0.2 4.0 GO:0033268 node of Ranvier(GO:0033268)
0.4 3.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.3 3.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 220 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 25.6 GO:0005178 integrin binding(GO:0005178)
0.7 19.2 GO:0001968 fibronectin binding(GO:0001968)
3.9 11.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
2.0 11.8 GO:0019841 retinol binding(GO:0019841)
0.2 11.6 GO:0046875 ephrin receptor binding(GO:0046875)
1.2 10.0 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.9 9.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8 9.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.3 8.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.4 8.5 GO:0045545 syndecan binding(GO:0045545)
1.1 7.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.9 7.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 7.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
1.3 6.6 GO:0042895 antibiotic transporter activity(GO:0042895)
0.2 6.4 GO:0050840 extracellular matrix binding(GO:0050840)
1.0 6.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.7 5.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 5.6 GO:0070097 delta-catenin binding(GO:0070097)
0.9 5.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 5.5 GO:0003777 microtubule motor activity(GO:0003777)