Motif ID: Pax6

Z-value: 0.601


Transcription factors associated with Pax6:

Gene SymbolEntrez IDGene Name
Pax6 ENSMUSG00000027168.15 Pax6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax6mm10_v2_chr2_+_105668935_1056689500.096.3e-01Click!


Activity profile for motif Pax6.

activity profile for motif Pax6


Sorted Z-values histogram for motif Pax6

Sorted Z-values for motif Pax6



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 78 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 3.870 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr17_+_43568096 2.514 ENSMUST00000167214.1
 Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr7_-_86775860 2.168 ENSMUST00000001824.5
 Folh1
folate hydrolase 1
chr7_-_86775808 2.035 ENSMUST00000107271.3
 Folh1
folate hydrolase 1
chr10_+_94550852 1.499 ENSMUST00000148910.1
ENSMUST00000117460.1
 Tmcc3

transmembrane and coiled coil domains 3

chr15_+_6299781 1.351 ENSMUST00000078019.6
 Dab2
disabled 2, mitogen-responsive phosphoprotein
chr11_-_67965631 1.209 ENSMUST00000021287.5
ENSMUST00000126766.1
 Wdr16

WD repeat domain 16

chr9_+_92250039 1.161 ENSMUST00000093801.3
 Plscr1
phospholipid scramblase 1
chr17_+_43016536 1.120 ENSMUST00000024708.4
 Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr5_-_74677792 1.073 ENSMUST00000117525.1
ENSMUST00000153543.1
ENSMUST00000039744.6
ENSMUST00000113531.2
ENSMUST00000121690.1
 Lnx1




ligand of numb-protein X 1




chr7_-_103843154 1.030 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr15_+_6299797 0.999 ENSMUST00000159046.1
ENSMUST00000161040.1
 Dab2

disabled 2, mitogen-responsive phosphoprotein

chr15_+_84669565 0.982 ENSMUST00000171460.1
 Prr5
proline rich 5 (renal)
chr17_-_43543639 0.941 ENSMUST00000178772.1
 Ankrd66
ankyrin repeat domain 66
chr5_-_38480131 0.878 ENSMUST00000143758.1
ENSMUST00000067886.5
 Slc2a9

solute carrier family 2 (facilitated glucose transporter), member 9

chr3_+_65109343 0.837 ENSMUST00000159525.1
ENSMUST00000049230.8
 Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr13_-_24937585 0.766 ENSMUST00000037615.6
 Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr13_-_113618549 0.739 ENSMUST00000109241.3
 Snx18
sorting nexin 18
chr3_+_98013503 0.733 ENSMUST00000079812.6
 Notch2
notch 2
chr11_+_78328415 0.725 ENSMUST00000048073.8
 Pigs
phosphatidylinositol glycan anchor biosynthesis, class S

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0006760 folic acid-containing compound metabolic process(GO:0006760)
0.5 2.5 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.5 2.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4 1.2 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.4 1.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.2 1.0 GO:0015671 oxygen transport(GO:0015671)
0.0 1.0 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 0.9 GO:0046415 urate metabolic process(GO:0046415)
0.3 0.8 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.2 0.7 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.2 0.7 GO:0061724 lipophagy(GO:0061724)
0.1 0.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.7 GO:0036089 cleavage furrow formation(GO:0036089)
0.2 0.6 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.2 0.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 0.5 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:1904355 positive regulation of telomere capping(GO:1904355)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.6 2.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.2 GO:0016805 dipeptidase activity(GO:0016805)
0.3 2.5 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.3 2.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 1.0 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.3 0.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.8 GO:0070402 NADPH binding(GO:0070402)
0.0 0.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.7 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.5 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294) delta-catenin binding(GO:0070097)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)