Motif ID: Pax7

Z-value: 0.403


Transcription factors associated with Pax7:

Gene SymbolEntrez IDGene Name
Pax7 ENSMUSG00000028736.7 Pax7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax7mm10_v2_chr4_-_139833524_139833535-0.411.9e-02Click!


Activity profile for motif Pax7.

activity profile for motif Pax7


Sorted Z-values histogram for motif Pax7

Sorted Z-values for motif Pax7



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_62766153 2.195 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_9436028 1.900 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr1_-_55226768 1.468 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr11_-_102946688 1.409 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr4_+_102589687 1.373 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr15_-_37459327 1.313 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr13_+_23533869 1.207 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr9_-_96719404 1.136 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr15_-_67113909 1.110 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr13_-_22042949 1.088 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr6_-_57535422 1.054 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr6_+_145934113 1.001 ENSMUST00000032383.7
Sspn
sarcospan
chr4_-_14621805 0.949 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr9_-_96719549 0.948 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr3_+_96268654 0.702 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chr11_-_115276973 0.700 ENSMUST00000021078.2
Fdxr
ferredoxin reductase
chr5_+_26817357 0.685 ENSMUST00000071500.6
Dpp6
dipeptidylpeptidase 6
chr3_+_55461758 0.675 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr13_-_23934156 0.638 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr15_-_64922290 0.628 ENSMUST00000023007.5
Adcy8
adenylate cyclase 8
chr11_-_87359011 0.523 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr4_+_136286061 0.484 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr8_-_34965631 0.437 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr11_-_29247208 0.375 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr1_+_72284367 0.340 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr18_+_38993126 0.297 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chr2_-_37359274 0.296 ENSMUST00000009174.8
Pdcl
phosducin-like
chr7_-_45510400 0.294 ENSMUST00000033096.7
Nucb1
nucleobindin 1
chr4_+_108719649 0.283 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr2_-_150255591 0.262 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chrX_+_9885622 0.235 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr9_-_71163224 0.233 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr14_-_76110760 0.227 ENSMUST00000022585.3
Gpalpp1
GPALPP motifs containing 1
chr4_-_14621494 0.216 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr14_+_55560010 0.202 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr3_+_32436376 0.198 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr17_-_35516780 0.188 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr10_-_62379852 0.188 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr2_+_125068118 0.181 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr5_-_92348871 0.178 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr13_+_22043189 0.173 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr7_-_98656530 0.171 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chrX_+_16619698 0.109 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr7_-_137410717 0.100 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr12_+_72441852 0.094 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr11_+_116843278 0.082 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr13_+_75707484 0.056 ENSMUST00000001583.6
Ell2
elongation factor RNA polymerase II 2
chr17_+_35517100 0.049 ENSMUST00000164242.2
ENSMUST00000045956.7
Cchcr1

coiled-coil alpha-helical rod protein 1

chr2_-_116067391 0.043 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr14_+_55559993 0.022 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr13_+_76579670 0.021 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0061743 motor learning(GO:0061743)
0.2 1.5 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.1 0.4 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.1 0.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0015791 polyol transport(GO:0015791) urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0007616 long-term memory(GO:0007616)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.7 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 1.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 2.1 GO:0006275 regulation of DNA replication(GO:0006275)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0044301 climbing fiber(GO:0044301)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 1.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 2.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 1.4 GO:0043015 cAMP binding(GO:0030552) gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)