Motif ID: Pax8

Z-value: 0.277


Transcription factors associated with Pax8:

Gene SymbolEntrez IDGene Name
Pax8 ENSMUSG00000026976.9 Pax8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax8mm10_v2_chr2_-_24475596_244756050.125.2e-01Click!


Activity profile for motif Pax8.

activity profile for motif Pax8


Sorted Z-values histogram for motif Pax8

Sorted Z-values for motif Pax8



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax8

PNG image of the network

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Top targets:


Showing 1 to 20 of 36 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_6961160 0.902 ENSMUST00000054055.6
Usp29
ubiquitin specific peptidase 29
chr18_-_66860458 0.663 ENSMUST00000057942.2
Mc4r
melanocortin 4 receptor
chr11_-_69801716 0.524 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr13_-_66852017 0.423 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr13_-_62607499 0.376 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr7_+_112742025 0.346 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr12_+_71048338 0.321 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr18_-_12121460 0.312 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
Tmem241


transmembrane protein 241


chr1_+_65186727 0.248 ENSMUST00000097707.4
ENSMUST00000081154.7
Pikfyve

phosphoinositide kinase, FYVE finger containing

chr13_-_62777089 0.244 ENSMUST00000167516.2
Gm5141
predicted gene 5141
chr4_+_6191093 0.232 ENSMUST00000029907.5
Ubxn2b
UBX domain protein 2B
chr9_+_32116040 0.231 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr11_+_24080664 0.228 ENSMUST00000118955.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr2_+_128967383 0.220 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr4_+_103313806 0.190 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr9_+_109052828 0.185 ENSMUST00000124432.1
Shisa5
shisa homolog 5 (Xenopus laevis)
chr13_-_62520451 0.183 ENSMUST00000082203.6
ENSMUST00000101547.4
Zfp934

zinc finger protein 934

chr7_-_29906087 0.172 ENSMUST00000053521.8
Zfp27
zinc finger protein 27
chr1_+_6487231 0.157 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr3_+_135212557 0.154 ENSMUST00000062893.7
Cenpe
centromere protein E

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.9 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883) positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)

Gene overrepresentation in cellular_component category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular_function category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.7 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)