Motif ID: Pax8

Z-value: 0.277


Transcription factors associated with Pax8:

Gene SymbolEntrez IDGene Name
Pax8 ENSMUSG00000026976.9 Pax8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax8mm10_v2_chr2_-_24475596_244756050.125.2e-01Click!


Activity profile for motif Pax8.

activity profile for motif Pax8


Sorted Z-values histogram for motif Pax8

Sorted Z-values for motif Pax8



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_6961160 0.902 ENSMUST00000054055.6
 Usp29
ubiquitin specific peptidase 29
chr18_-_66860458 0.663 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr11_-_69801716 0.524 ENSMUST00000011285.4
ENSMUST00000102585.1
 Fgf11

fibroblast growth factor 11

chr13_-_66852017 0.423 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr13_-_62607499 0.376 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr7_+_112742025 0.346 ENSMUST00000164363.1
 Tead1
TEA domain family member 1
chr12_+_71048338 0.321 ENSMUST00000135709.1
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr18_-_12121460 0.312 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
 Tmem241


transmembrane protein 241


chr1_+_65186727 0.248 ENSMUST00000097707.4
ENSMUST00000081154.7
 Pikfyve

phosphoinositide kinase, FYVE finger containing

chr13_-_62777089 0.244 ENSMUST00000167516.2
 Gm5141
predicted gene 5141
chr4_+_6191093 0.232 ENSMUST00000029907.5
 Ubxn2b
UBX domain protein 2B
chr9_+_32116040 0.231 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr11_+_24080664 0.228 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr2_+_128967383 0.220 ENSMUST00000110320.2
ENSMUST00000110319.2
 Zc3h6

zinc finger CCCH type containing 6

chr4_+_103313806 0.190 ENSMUST00000035780.3
 Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr9_+_109052828 0.185 ENSMUST00000124432.1
 Shisa5
shisa homolog 5 (Xenopus laevis)
chr13_-_62520451 0.183 ENSMUST00000082203.6
ENSMUST00000101547.4
 Zfp934

zinc finger protein 934

chr7_-_29906087 0.172 ENSMUST00000053521.8
 Zfp27
zinc finger protein 27
chr1_+_6487231 0.157 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr3_+_135212557 0.154 ENSMUST00000062893.7
 Cenpe
centromere protein E
chr7_-_42578588 0.153 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr9_-_103230415 0.144 ENSMUST00000035158.9
 Trf
transferrin
chr4_+_156215920 0.136 ENSMUST00000105572.1
 2310042D19Rik
RIKEN cDNA 2310042D19 gene
chrX_-_105391726 0.135 ENSMUST00000142109.1
 5330434G04Rik
RIKEN cDNA 5330434G04 gene
chr17_+_45555693 0.098 ENSMUST00000024742.7
 Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr8_-_64849818 0.092 ENSMUST00000034017.7
 Klhl2
kelch-like 2, Mayven
chrX_-_105391770 0.090 ENSMUST00000136406.1
ENSMUST00000150604.1
 5330434G04Rik

RIKEN cDNA 5330434G04 gene

chr2_+_177508570 0.085 ENSMUST00000108940.2
 Gm14403
predicted gene 14403
chr4_+_59805829 0.080 ENSMUST00000030080.6
 Snx30
sorting nexin family member 30
chr13_-_25270076 0.069 ENSMUST00000057866.6
 Nrsn1
neurensin 1
chr1_+_74542881 0.065 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
 Plcd4




phospholipase C, delta 4




chr12_-_20900867 0.062 ENSMUST00000079237.5
 Zfp125
zinc finger protein 125
chrX_+_82948861 0.062 ENSMUST00000114000.1
 Dmd
dystrophin, muscular dystrophy
chr17_+_21691860 0.019 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chrX_-_7572843 0.003 ENSMUST00000132788.1
 Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr7_-_42706369 0.003 ENSMUST00000180131.1
 Gm17067
predicted gene 17067

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883) positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)