Motif ID: Pbx1_Pbx3

Z-value: 1.227

Transcription factors associated with Pbx1_Pbx3:

Gene SymbolEntrez IDGene Name
Pbx1 ENSMUSG00000052534.9 Pbx1
Pbx3 ENSMUSG00000038718.9 Pbx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pbx1mm10_v2_chr1_-_168431896_168431905-0.832.3e-09Click!
Pbx3mm10_v2_chr2_-_34372004_343720440.392.5e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pbx1_Pbx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_85688252 15.049 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr9_-_63711969 11.729 ENSMUST00000154323.1
Smad3
SMAD family member 3
chr14_-_48667508 8.308 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr4_-_3938354 7.549 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr12_+_72939724 7.524 ENSMUST00000021519.5
Six6
sine oculis-related homeobox 6
chr17_-_70853482 6.881 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr19_+_55894508 6.066 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr17_+_85620816 5.792 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr4_-_43523388 5.557 ENSMUST00000107913.3
ENSMUST00000030184.5
Tpm2

tropomyosin 2, beta

chr19_+_55741810 5.513 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr3_+_37639985 5.509 ENSMUST00000108107.1
Spry1
sprouty homolog 1 (Drosophila)
chr13_+_15463837 5.384 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr4_-_43523746 5.359 ENSMUST00000150592.1
Tpm2
tropomyosin 2, beta
chr4_+_3938888 5.326 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr3_+_37639945 5.206 ENSMUST00000108109.1
ENSMUST00000038569.1
Spry1

sprouty homolog 1 (Drosophila)

chr17_+_47596061 5.195 ENSMUST00000182539.1
Ccnd3
cyclin D3
chr5_+_103425181 5.045 ENSMUST00000048957.9
Ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr4_-_43523595 4.843 ENSMUST00000107914.3
Tpm2
tropomyosin 2, beta
chr1_-_183147461 4.772 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr19_-_9899450 4.653 ENSMUST00000025562.7
Incenp
inner centromere protein
chr10_-_40302186 4.555 ENSMUST00000099945.4
Amd1
S-adenosylmethionine decarboxylase 1
chr19_-_12501996 4.551 ENSMUST00000045521.7
Dtx4
deltex 4 homolog (Drosophila)
chr5_-_67427794 4.355 ENSMUST00000169190.1
Bend4
BEN domain containing 4
chrX_-_52165252 4.330 ENSMUST00000033450.2
Gpc4
glypican 4
chrX_-_141474034 4.133 ENSMUST00000101205.2
Col4a6
collagen, type IV, alpha 6
chr7_-_127273919 4.052 ENSMUST00000082428.3
Sephs2
selenophosphate synthetase 2
chrX_+_58030622 3.925 ENSMUST00000088627.4
Zic3
zinc finger protein of the cerebellum 3
chr11_-_19018956 3.905 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr13_+_44730726 3.776 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr4_-_129189600 3.616 ENSMUST00000117497.1
ENSMUST00000117350.1
S100pbp

S100P binding protein

chr4_-_115939923 3.598 ENSMUST00000124071.2
ENSMUST00000084338.6
Dmbx1

diencephalon/mesencephalon homeobox 1

chr9_+_106281061 3.551 ENSMUST00000072206.6
Poc1a
POC1 centriolar protein homolog A (Chlamydomonas)
chr3_-_154328634 3.477 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr2_+_109917639 3.437 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr17_+_85621017 3.407 ENSMUST00000162695.2
Six3
sine oculis-related homeobox 3
chr8_-_116732991 3.316 ENSMUST00000109102.2
Cdyl2
chromodomain protein, Y chromosome-like 2
chr3_-_8667033 3.216 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr18_-_77047243 3.160 ENSMUST00000137354.1
ENSMUST00000137498.1
Katnal2

katanin p60 subunit A-like 2

chr14_+_25694170 3.082 ENSMUST00000022419.6
Ppif
peptidylprolyl isomerase F (cyclophilin F)
chr11_-_22001605 3.080 ENSMUST00000006071.7
Otx1
orthodenticle homolog 1 (Drosophila)
chr10_-_78009737 3.036 ENSMUST00000020522.8
Pfkl
phosphofructokinase, liver, B-type
chr11_+_106084577 2.982 ENSMUST00000002044.9
Map3k3
mitogen-activated protein kinase kinase kinase 3
chr18_-_77047282 2.935 ENSMUST00000154665.1
ENSMUST00000026486.6
ENSMUST00000123650.1
ENSMUST00000126153.1
Katnal2



katanin p60 subunit A-like 2



chr11_-_19018714 2.773 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr7_+_139389072 2.736 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr9_-_37147257 2.694 ENSMUST00000039674.5
ENSMUST00000080754.5
Pknox2

Pbx/knotted 1 homeobox 2

chr14_-_61037937 2.673 ENSMUST00000111236.2
Tnfrsf19
tumor necrosis factor receptor superfamily, member 19
chr7_+_141475459 2.671 ENSMUST00000138092.1
ENSMUST00000146305.1
Tspan4

tetraspanin 4

chr4_-_129189512 2.646 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
S100pbp


S100P binding protein


chr2_+_27886416 2.608 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr10_-_119240006 2.574 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chr7_+_141475240 2.559 ENSMUST00000026585.7
Tspan4
tetraspanin 4
chr4_-_129189646 2.550 ENSMUST00000106059.1
S100pbp
S100P binding protein
chr19_-_14598031 2.531 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr14_+_99046406 2.507 ENSMUST00000022656.6
Bora
bora, aurora kinase A activator
chr14_-_122465677 2.501 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr13_-_106936907 2.461 ENSMUST00000080856.7
Ipo11
importin 11
chr17_-_30612613 2.444 ENSMUST00000167624.1
ENSMUST00000024823.6
Glo1

glyoxalase 1

chr4_-_137048695 2.388 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr3_-_53657339 2.338 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr16_+_17233560 2.303 ENSMUST00000090190.5
ENSMUST00000115698.2
Hic2

hypermethylated in cancer 2

chr16_+_30065333 2.285 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr9_-_109082372 2.279 ENSMUST00000167504.1
Tma7
translational machinery associated 7 homolog (S. cerevisiae)
chr6_-_49214954 2.270 ENSMUST00000031838.7
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr5_+_115011111 2.263 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chr11_-_80080928 2.210 ENSMUST00000103233.3
ENSMUST00000061283.8
Crlf3

cytokine receptor-like factor 3

chrX_-_60893430 2.204 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr8_+_105900421 2.200 ENSMUST00000049699.8
Pskh1
protein serine kinase H1
chr4_+_129820198 2.166 ENSMUST00000030578.7
Ptp4a2
protein tyrosine phosphatase 4a2
chrX_-_8074720 2.144 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr11_-_96005872 2.143 ENSMUST00000013559.2
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr18_+_82475133 2.113 ENSMUST00000091789.4
ENSMUST00000114676.1
ENSMUST00000047865.7
Mbp


myelin basic protein


chr3_+_88579602 2.090 ENSMUST00000035785.7
Ssr2
signal sequence receptor, beta
chr13_+_91461050 2.038 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2

single-stranded DNA binding protein 2

chr4_+_11579647 2.037 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr19_+_55742242 2.032 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr10_-_41809607 2.027 ENSMUST00000019951.9
Cep57l1
centrosomal protein 57-like 1
chrX_+_101429555 1.999 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chrX_-_134808984 1.983 ENSMUST00000035559.4
Armcx2
armadillo repeat containing, X-linked 2
chr10_-_42583628 1.955 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr9_-_21760275 1.933 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr17_-_56830916 1.854 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr8_+_106603351 1.851 ENSMUST00000000312.5
ENSMUST00000167688.1
Cdh1

cadherin 1

chr6_+_34476207 1.823 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
Bpgm


2,3-bisphosphoglycerate mutase


chr19_+_55742056 1.800 ENSMUST00000111659.2
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr9_-_100546053 1.780 ENSMUST00000116522.1
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr17_-_56290499 1.722 ENSMUST00000019726.6
Plin3
perilipin 3
chr15_+_99702278 1.718 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr19_+_55741884 1.700 ENSMUST00000111658.3
ENSMUST00000111654.1
Tcf7l2

transcription factor 7 like 2, T cell specific, HMG box

chr5_+_92897981 1.700 ENSMUST00000113051.2
Shroom3
shroom family member 3
chr18_+_60925644 1.692 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr18_+_60925612 1.689 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr9_+_113930934 1.684 ENSMUST00000084885.5
ENSMUST00000009885.7
Ubp1

upstream binding protein 1

chr5_+_73491026 1.661 ENSMUST00000063882.5
ENSMUST00000113558.1
Dcun1d4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr15_-_83464570 1.659 ENSMUST00000056177.6
Pacsin2
protein kinase C and casein kinase substrate in neurons 2
chrX_+_106187100 1.659 ENSMUST00000081593.6
Pgk1
phosphoglycerate kinase 1
chr11_+_55469677 1.628 ENSMUST00000018727.3
G3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr11_+_64435315 1.628 ENSMUST00000058652.5
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr8_-_91801948 1.611 ENSMUST00000175795.1
Irx3
Iroquois related homeobox 3 (Drosophila)
chr2_-_125506385 1.602 ENSMUST00000028633.6
Fbn1
fibrillin 1
chr2_-_121271315 1.581 ENSMUST00000131245.1
Trp53bp1
transformation related protein 53 binding protein 1
chr2_+_157279065 1.580 ENSMUST00000029171.5
Rpn2
ribophorin II
chr2_+_157279026 1.570 ENSMUST00000116380.2
Rpn2
ribophorin II
chr2_+_121295437 1.548 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chr12_-_54986328 1.546 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr14_-_52104015 1.489 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr15_-_83464595 1.472 ENSMUST00000171436.1
Pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr8_+_23411490 1.470 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr11_-_106998483 1.469 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr15_-_8099182 1.460 ENSMUST00000045766.6
Wdr70
WD repeat domain 70
chr8_-_122611419 1.456 ENSMUST00000015171.9
Galns
galactosamine (N-acetyl)-6-sulfate sulfatase
chr12_-_54986363 1.447 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr14_-_104467984 1.446 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr5_-_138172383 1.440 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr10_+_20148457 1.393 ENSMUST00000020173.8
Map7
microtubule-associated protein 7
chr4_-_72200833 1.389 ENSMUST00000102848.2
ENSMUST00000072695.6
ENSMUST00000107337.1
ENSMUST00000074216.7
Tle1



transducin-like enhancer of split 1, homolog of Drosophila E(spl)



chr1_-_75506331 1.384 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr12_-_83921809 1.381 ENSMUST00000135962.1
ENSMUST00000155112.1
ENSMUST00000136848.1
ENSMUST00000126943.1
Numb



numb gene homolog (Drosophila)



chr13_+_72628802 1.376 ENSMUST00000074372.4
Irx2
Iroquois related homeobox 2 (Drosophila)
chr7_-_113347273 1.376 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr9_+_96258697 1.362 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr10_-_116549101 1.328 ENSMUST00000164088.1
Cnot2
CCR4-NOT transcription complex, subunit 2
chr17_-_24960620 1.320 ENSMUST00000024981.7
Hn1l
hematological and neurological expressed 1-like
chr11_-_89538556 1.313 ENSMUST00000169201.1
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr11_-_100441795 1.284 ENSMUST00000107398.1
Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr15_+_37233036 1.281 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
Grhl2


grainyhead-like 2 (Drosophila)


chr17_-_3557713 1.260 ENSMUST00000041003.6
Tfb1m
transcription factor B1, mitochondrial
chr5_-_115436508 1.258 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chrX_+_136270253 1.258 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr5_-_138171813 1.257 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr16_+_21204755 1.256 ENSMUST00000006112.6
Ephb3
Eph receptor B3
chr8_+_83972951 1.214 ENSMUST00000005606.6
Prkaca
protein kinase, cAMP dependent, catalytic, alpha
chrX_+_136270302 1.214 ENSMUST00000113112.1
Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_+_34772089 1.213 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr16_+_64851991 1.190 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr8_+_124231359 1.161 ENSMUST00000034458.8
Galnt2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2
chr7_-_141475131 1.158 ENSMUST00000043870.8
Polr2l
polymerase (RNA) II (DNA directed) polypeptide L
chr16_-_35363842 1.145 ENSMUST00000043521.4
Sec22a
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
chr10_+_79854658 1.140 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr5_+_21372642 1.132 ENSMUST00000035799.5
Fgl2
fibrinogen-like protein 2
chr14_+_46832127 1.127 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr6_-_52640303 1.126 ENSMUST00000031788.8
Hibadh
3-hydroxyisobutyrate dehydrogenase
chr11_-_96829904 1.114 ENSMUST00000107657.1
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr7_+_45434876 1.102 ENSMUST00000107766.1
Gys1
glycogen synthase 1, muscle
chr4_+_41760454 1.094 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr4_-_151057933 1.087 ENSMUST00000030797.3
Vamp3
vesicle-associated membrane protein 3
chr12_-_76709997 1.084 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr8_-_107403197 1.076 ENSMUST00000003947.8
Nqo1
NAD(P)H dehydrogenase, quinone 1
chr2_-_121271403 1.072 ENSMUST00000110648.1
Trp53bp1
transformation related protein 53 binding protein 1
chr3_+_133338936 1.068 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr8_+_75033673 1.067 ENSMUST00000078847.5
ENSMUST00000165630.1
Tom1

target of myb1 homolog (chicken)

chrX_-_73930751 1.064 ENSMUST00000155597.1
ENSMUST00000114379.1
Renbp

renin binding protein

chr11_-_87108656 1.052 ENSMUST00000051395.8
Prr11
proline rich 11
chr10_-_13324250 1.050 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr2_+_172549581 1.046 ENSMUST00000030391.2
Tfap2c
transcription factor AP-2, gamma
chr5_-_100500592 1.043 ENSMUST00000149714.1
ENSMUST00000046154.5
Lin54

lin-54 homolog (C. elegans)

chr17_+_25240166 1.042 ENSMUST00000063574.6
Tsr3
TSR3 20S rRNA accumulation
chr12_-_83921899 1.037 ENSMUST00000117217.1
Numb
numb gene homolog (Drosophila)
chrX_-_53370470 1.012 ENSMUST00000096447.2
ENSMUST00000023836.3
Mospd1

motile sperm domain containing 1

chr17_+_31564749 1.008 ENSMUST00000175806.1
ENSMUST00000097352.3
Pknox1

Pbx/knotted 1 homeobox

chrX_-_95444789 1.007 ENSMUST00000084535.5
Amer1
APC membrane recruitment 1
chr10_+_77978524 1.006 ENSMUST00000105397.3
ENSMUST00000105398.1
1810043G02Rik

RIKEN cDNA 1810043G02 gene

chr12_+_36314160 0.999 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr4_+_98395817 0.989 ENSMUST00000107033.1
ENSMUST00000107034.1
Inadl

InaD-like (Drosophila)

chr5_-_36988922 0.983 ENSMUST00000166339.1
ENSMUST00000043964.6
Wfs1

Wolfram syndrome 1 homolog (human)

chr7_+_100495987 0.983 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chrY_-_6681243 0.980 ENSMUST00000115940.1
Gm21719
predicted gene, 21719
chr2_+_158794807 0.976 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr11_-_5803733 0.973 ENSMUST00000020768.3
Pgam2
phosphoglycerate mutase 2
chr7_+_27486910 0.969 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr10_+_79854618 0.966 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chr6_-_113419310 0.959 ENSMUST00000147726.1
ENSMUST00000151618.1
ENSMUST00000060634.7
ENSMUST00000129047.1
ENSMUST00000129560.1
ENSMUST00000113092.2
Rpusd3





RNA pseudouridylate synthase domain containing 3





chr8_-_22060305 0.953 ENSMUST00000006742.4
Atp7b
ATPase, Cu++ transporting, beta polypeptide
chr16_+_94570010 0.949 ENSMUST00000119878.1
Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr8_-_46152159 0.939 ENSMUST00000110378.2
Snx25
sorting nexin 25
chrX_-_73930834 0.933 ENSMUST00000116578.1
Renbp
renin binding protein
chr2_+_173737492 0.929 ENSMUST00000067530.4
Vapb
vesicle-associated membrane protein, associated protein B and C
chr7_+_45434833 0.926 ENSMUST00000003964.8
Gys1
glycogen synthase 1, muscle
chr17_+_35841668 0.909 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr3_-_90433603 0.907 ENSMUST00000029542.5
ENSMUST00000071488.3
Ints3

integrator complex subunit 3

chr7_+_142533012 0.899 ENSMUST00000038675.6
Mrpl23
mitochondrial ribosomal protein L23
chr7_-_45434590 0.885 ENSMUST00000107771.3
ENSMUST00000141761.1
Ruvbl2

RuvB-like protein 2

chr2_-_126618655 0.882 ENSMUST00000028838.4
Hdc
histidine decarboxylase
chr11_+_60537978 0.866 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr5_+_34761734 0.857 ENSMUST00000080036.2
Htt
huntingtin
chr13_-_64153194 0.852 ENSMUST00000059817.4
ENSMUST00000117241.1
Zfp367

zinc finger protein 367

chr4_+_129189760 0.845 ENSMUST00000106054.2
ENSMUST00000001365.2
Yars

tyrosyl-tRNA synthetase

chr13_-_71963713 0.829 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr6_-_54593139 0.827 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr14_-_65425453 0.816 ENSMUST00000059339.5
Pnoc
prepronociceptin
chr7_+_28810886 0.815 ENSMUST00000038572.8
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr2_+_91257323 0.802 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr13_-_119408985 0.797 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr17_-_14694223 0.796 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr2_-_18048347 0.787 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr17_-_50094277 0.780 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr11_+_103774150 0.770 ENSMUST00000000127.5
Wnt3
wingless-related MMTV integration site 3
chr11_-_96829959 0.766 ENSMUST00000081775.5
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr3_-_96905294 0.733 ENSMUST00000029738.7
Gpr89
G protein-coupled receptor 89
chr17_-_34959232 0.731 ENSMUST00000165202.1
ENSMUST00000172753.1
Hspa1b

heat shock protein 1B


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.7 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
3.8 15.0 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
3.1 9.2 GO:0097402 neuroblast migration(GO:0097402)
2.1 10.7 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
2.1 17.1 GO:0048625 myoblast fate commitment(GO:0048625)
2.1 8.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.8 5.4 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.5 4.6 GO:0006597 spermine biosynthetic process(GO:0006597)
1.1 3.4 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.0 3.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
1.0 4.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.9 2.8 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.9 2.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.8 2.4 GO:0030862 neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.8 2.3 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.7 3.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.6 3.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.6 3.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.5 1.6 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.5 1.5 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.5 1.4 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.5 7.5 GO:0060736 prostate gland growth(GO:0060736)
0.4 3.6 GO:0008343 adult feeding behavior(GO:0008343)
0.4 1.8 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.4 4.8 GO:0060539 diaphragm development(GO:0060539)
0.4 2.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 2.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.4 1.3 GO:0060672 negative regulation of keratinocyte differentiation(GO:0045617) epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 1.2 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.4 2.0 GO:0021764 amygdala development(GO:0021764)
0.4 6.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 3.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 1.5 GO:0090365 regulation of mRNA modification(GO:0090365)
0.4 1.9 GO:0060066 oviduct development(GO:0060066) response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.3 1.0 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.3 3.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.3 0.3 GO:0061074 regulation of neural retina development(GO:0061074)
0.3 1.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.3 1.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.3 1.0 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 3.0 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 4.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.3 0.9 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3 6.7 GO:0035855 megakaryocyte development(GO:0035855)
0.3 1.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 5.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 0.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 2.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.3 3.1 GO:0070836 caveola assembly(GO:0070836)
0.3 1.7 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.3 2.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 0.8 GO:0060174 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) limb bud formation(GO:0060174)
0.3 2.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 1.2 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.2 2.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.2 2.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.2 0.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 2.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 2.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.9 GO:0006547 histidine metabolic process(GO:0006547)
0.2 0.9 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2 0.6 GO:0070543 response to linoleic acid(GO:0070543)
0.2 0.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 1.0 GO:0001778 plasma membrane repair(GO:0001778)
0.2 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.2 1.4 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.2 2.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 1.3 GO:0050957 equilibrioception(GO:0050957)
0.2 1.9 GO:0001675 acrosome assembly(GO:0001675)
0.2 0.5 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2 0.7 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 1.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2 0.6 GO:1903998 regulation of eating behavior(GO:1903998)
0.2 2.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 2.2 GO:0007530 sex determination(GO:0007530)
0.2 0.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 0.6 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.2 2.7 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 0.7 GO:0060346 bone trabecula formation(GO:0060346)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 1.0 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 1.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.4 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 2.3 GO:0045116 protein neddylation(GO:0045116)
0.1 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 2.0 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.3 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 6.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 1.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:0015862 uridine transport(GO:0015862)
0.1 1.1 GO:0046697 decidualization(GO:0046697)
0.1 2.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.1 GO:0006573 valine metabolic process(GO:0006573)
0.1 0.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.3 GO:0007413 axonal fasciculation(GO:0007413)
0.1 1.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 3.5 GO:0021884 forebrain neuron development(GO:0021884)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.4 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.1 1.0 GO:0015677 copper ion import(GO:0015677)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.3 GO:0097298 regulation of nucleus size(GO:0097298)
0.1 0.9 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 2.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.1 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 0.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 5.0 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1 0.4 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.4 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 2.2 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 1.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 1.0 GO:0019835 cytolysis(GO:0019835)
0.1 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.3 GO:0000154 rRNA modification(GO:0000154)
0.0 0.4 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.9 GO:0016180 snRNA processing(GO:0016180)
0.0 2.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 2.7 GO:0001942 hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405) skin epidermis development(GO:0098773)
0.0 4.7 GO:0000910 cytokinesis(GO:0000910)
0.0 1.2 GO:0051693 actin filament capping(GO:0051693)
0.0 1.7 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.4 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 1.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 7.6 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 1.4 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 2.9 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 2.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.5 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.8 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.2 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 1.6 GO:0007498 mesoderm development(GO:0007498)
0.0 0.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.6 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.3 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.7 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 2.0 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 3.1 GO:0001654 eye development(GO:0001654)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.4 GO:0006220 pyrimidine nucleotide metabolic process(GO:0006220)
0.0 0.1 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 1.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.8 GO:1901343 negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 0.0 GO:0070973 vesicle coating(GO:0006901) COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 4.9 GO:0006281 DNA repair(GO:0006281)
0.0 1.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.8 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.5 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.9 GO:0006338 chromatin remodeling(GO:0006338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
1.9 17.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
1.8 15.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.6 4.7 GO:0000801 central element(GO:0000801)
0.9 2.6 GO:0005588 collagen type V trimer(GO:0005588)
0.9 1.7 GO:0071564 npBAF complex(GO:0071564)
0.8 4.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.8 3.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 3.0 GO:0008623 CHRAC(GO:0008623)
0.6 3.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.5 2.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.4 2.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.4 2.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 0.7 GO:0030315 T-tubule(GO:0030315)
0.3 1.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 1.9 GO:0031262 Ndc80 complex(GO:0031262)
0.3 2.5 GO:0072687 meiotic spindle(GO:0072687)
0.3 3.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 2.1 GO:0033269 internode region of axon(GO:0033269)
0.3 2.0 GO:0042382 paraspeckles(GO:0042382)
0.2 1.9 GO:0043219 lateral loop(GO:0043219)
0.2 2.8 GO:0046930 pore complex(GO:0046930)
0.2 1.2 GO:0005796 Golgi lumen(GO:0005796)
0.2 0.9 GO:0070876 SOSS complex(GO:0070876)
0.2 1.1 GO:0008091 spectrin(GO:0008091)
0.2 2.7 GO:0042555 MCM complex(GO:0042555)
0.2 1.0 GO:0097513 myosin II filament(GO:0097513)
0.2 3.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.9 GO:0045120 pronucleus(GO:0045120)
0.1 1.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.8 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.1 1.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 5.4 GO:0016592 mediator complex(GO:0016592)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.1 1.6 GO:0001527 microfibril(GO:0001527)
0.1 5.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.5 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 3.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 3.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.8 GO:0031091 platelet alpha granule(GO:0031091)
0.1 1.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 3.2 GO:1990391 DNA repair complex(GO:1990391)
0.1 1.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 5.0 GO:0030496 midbody(GO:0030496)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.6 GO:0000922 spindle pole(GO:0000922)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0016234 inclusion body(GO:0016234)
0.0 14.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.4 GO:0030426 growth cone(GO:0030426)
0.0 8.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.1 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0043235 receptor complex(GO:0043235)
0.0 1.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 4.3 GO:0005829 cytosol(GO:0005829)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 5.6 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.9 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.7 GO:0005769 early endosome(GO:0005769)
0.0 4.8 GO:0005912 adherens junction(GO:0005912)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
1.1 4.6 GO:0019808 polyamine binding(GO:0019808)
1.1 3.2 GO:0035939 microsatellite binding(GO:0035939)
0.9 2.8 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.8 19.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.8 3.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.8 3.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.7 2.7 GO:0042731 PH domain binding(GO:0042731)
0.6 6.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.6 10.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 2.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 3.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 1.7 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4 6.9 GO:0070410 co-SMAD binding(GO:0070410)
0.4 1.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 4.8 GO:0015197 peptide transporter activity(GO:0015197)
0.3 1.0 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3 2.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 3.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.3 4.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 1.1 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 1.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 2.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 1.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 2.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 9.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 0.9 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 16.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 3.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.6 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 3.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 1.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 1.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 1.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.2 2.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 3.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 0.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.4 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 2.5 GO:0005123 death receptor binding(GO:0005123)
0.1 2.0 GO:0005536 glucose binding(GO:0005536)
0.1 0.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 10.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.9 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 10.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.0 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.8 GO:0001515 opioid peptide activity(GO:0001515)
0.1 3.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 2.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 5.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 38.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 3.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 8.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 2.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 6.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 3.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 3.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.7 GO:0030332 cyclin binding(GO:0030332)
0.1 6.5 GO:0005178 integrin binding(GO:0005178)
0.1 2.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.2 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 2.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.9 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 1.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 2.5 GO:0002020 protease binding(GO:0002020)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.6 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.8 GO:0050661 NADP binding(GO:0050661)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 1.4 GO:0001047 core promoter binding(GO:0001047)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 1.7 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889) acetylcholine binding(GO:0042166)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)