Motif ID: Pitx3

Z-value: 0.647


Transcription factors associated with Pitx3:

Gene SymbolEntrez IDGene Name
Pitx3 ENSMUSG00000025229.9 Pitx3



Activity profile for motif Pitx3.

activity profile for motif Pitx3


Sorted Z-values histogram for motif Pitx3

Sorted Z-values for motif Pitx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_7909542 1.747 ENSMUST00000086274.2
 Gm10490
predicted gene 10490
chr5_+_90759299 1.399 ENSMUST00000031318.4
 Cxcl5
chemokine (C-X-C motif) ligand 5
chr16_+_17276291 1.378 ENSMUST00000164950.1
ENSMUST00000159242.1
 Tmem191c

transmembrane protein 191C

chr11_-_79296906 1.281 ENSMUST00000068448.2
 Gm9964
predicted gene 9964
chr10_-_62899118 1.171 ENSMUST00000174189.1
 Tet1
tet methylcytosine dioxygenase 1
chr1_+_85575676 1.000 ENSMUST00000178024.1
 G530012D18Rik
RIKEN cDNA G530012D1 gene
chr17_-_32189457 0.983 ENSMUST00000087721.3
ENSMUST00000162117.1
 Ephx3

epoxide hydrolase 3

chr1_-_153408429 0.967 ENSMUST00000097535.4
 E330020D12Rik
Riken cDNA E330020D12 gene
chr10_+_81718919 0.920 ENSMUST00000085664.5
 Zfp433
RIKEN cDNA 1700123A16 gene
chr17_-_71460395 0.914 ENSMUST00000180522.1
 Gm4707
predicted gene 4707
chr17_-_35188427 0.906 ENSMUST00000097336.4
 Lst1
leukocyte specific transcript 1
chr7_+_18987518 0.883 ENSMUST00000063563.7
 Nanos2
nanos homolog 2 (Drosophila)
chrY_+_818646 0.867 ENSMUST00000115894.1
 Uba1y
ubiquitin-activating enzyme, Chr Y
chr17_+_94873986 0.863 ENSMUST00000108007.4
 Gm20939
predicted gene, 20939
chr1_-_133701881 0.848 ENSMUST00000167348.1
 Gm17678
predicted gene, 17678
chr11_+_102041509 0.839 ENSMUST00000123895.1
ENSMUST00000017453.5
ENSMUST00000107163.2
ENSMUST00000107164.2
 Cd300lg



CD300 antigen like family member G



chr5_+_138280538 0.838 ENSMUST00000162245.1
ENSMUST00000161691.1
 Stag3

stromal antigen 3

chr2_+_28506095 0.837 ENSMUST00000074761.4
 Gm10134
predicted gene 10134
chr13_-_67609617 0.835 ENSMUST00000138725.1
 AA987161
expressed sequence AA987161
chr7_-_81855794 0.825 ENSMUST00000085094.3
 Gm10160
predicted gene 10160

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0001824 blastocyst development(GO:0001824)
0.5 2.0 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.5 1.4 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 1.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 1.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 1.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 1.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 1.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 0.9 GO:0044838 cell quiescence(GO:0044838)
0.1 0.8 GO:0045056 transcytosis(GO:0045056)
0.1 0.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.7 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.7 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.6 GO:0001783 B cell apoptotic process(GO:0001783)
0.2 0.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 0.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.5 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.0 GO:0000802 transverse filament(GO:0000802)
0.1 0.7 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.4 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:1904949 ATPase complex(GO:1904949)
0.0 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.8 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.5 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)