Motif ID: Plagl1

Z-value: 0.513


Transcription factors associated with Plagl1:

Gene SymbolEntrez IDGene Name
Plagl1 ENSMUSG00000019817.12 Plagl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plagl1mm10_v2_chr10_+_13090788_13090843-0.354.7e-02Click!


Activity profile for motif Plagl1.

activity profile for motif Plagl1


Sorted Z-values histogram for motif Plagl1

Sorted Z-values for motif Plagl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plagl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 132 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_56535047 3.346 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr9_+_72806874 2.195 ENSMUST00000055535.8
 Prtg
protogenin homolog (Gallus gallus)
chr6_+_4504814 2.043 ENSMUST00000141483.1
 Col1a2
collagen, type I, alpha 2
chr17_-_84682932 1.554 ENSMUST00000066175.3
 Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr17_-_24644933 1.344 ENSMUST00000019684.5
 Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr10_+_80016901 1.313 ENSMUST00000105373.1
 Hmha1
histocompatibility (minor) HA-1
chr10_-_60831571 1.303 ENSMUST00000077925.5
 Unc5b
unc-5 homolog B (C. elegans)
chr7_-_4515959 1.285 ENSMUST00000163710.1
ENSMUST00000166268.1
ENSMUST00000071798.6
ENSMUST00000178163.1
ENSMUST00000108587.2
 Tnnt1




troponin T1, skeletal, slow




chr17_+_34593388 1.200 ENSMUST00000174532.1
 Pbx2
pre B cell leukemia homeobox 2
chr5_-_136883115 1.182 ENSMUST00000057497.6
ENSMUST00000111103.1
 Col26a1

collagen, type XXVI, alpha 1

chrX_+_99821021 1.101 ENSMUST00000096363.2
 Tmem28
transmembrane protein 28
chr6_-_128438673 1.016 ENSMUST00000032508.4
 Fkbp4
FK506 binding protein 4
chr4_+_47288057 1.004 ENSMUST00000140413.1
ENSMUST00000107731.2
 Col15a1

collagen, type XV, alpha 1

chr14_-_54864055 0.942 ENSMUST00000142283.2
 Homez
homeodomain leucine zipper-encoding gene
chr9_+_106453838 0.876 ENSMUST00000024260.6
 Pcbp4
poly(rC) binding protein 4
chr9_+_57998036 0.858 ENSMUST00000181289.1
 Gm17322
predicted gene, 17322
chr9_+_62342449 0.841 ENSMUST00000156461.1
 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr8_-_40634750 0.833 ENSMUST00000173957.1
 Mtmr7
myotubularin related protein 7
chr9_+_62342059 0.821 ENSMUST00000135395.1
 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr15_-_52478228 0.808 ENSMUST00000081993.1
 Gm10020
predicted pseudogene 10020

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.3 GO:0021759 globus pallidus development(GO:0021759)
0.2 2.0 GO:0043589 skin morphogenesis(GO:0043589)
0.1 1.7 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.5 1.6 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.1 1.6 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 1.6 GO:0051028 mRNA transport(GO:0051028)
0.0 1.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.2 1.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 1.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.1 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 1.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.9 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.8 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.8 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.0 2.5 GO:0016363 nuclear matrix(GO:0016363)
0.7 2.0 GO:0005584 collagen type I trimer(GO:0005584)
0.0 1.8 GO:0032420 stereocilium(GO:0032420)
0.2 1.6 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.3 1.3 GO:0005861 troponin complex(GO:0005861)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.5 GO:0008091 spectrin(GO:0008091)
0.1 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 2.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.1 1.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 1.6 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.3 1.3 GO:0031014 troponin T binding(GO:0031014)
0.2 1.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.2 1.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.6 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.6 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.1 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)