Motif ID: Pou2f2_Pou3f1

Z-value: 1.452

Transcription factors associated with Pou2f2_Pou3f1:

Gene SymbolEntrez IDGene Name
Pou2f2 ENSMUSG00000008496.12 Pou2f2
Pou3f1 ENSMUSG00000090125.2 Pou3f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f1mm10_v2_chr4_+_124657646_1246576560.345.6e-02Click!
Pou2f2mm10_v2_chr7_-_25132473_251325120.096.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 191 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_24507099 18.349 ENSMUST00000177228.1
Zfp428
zinc finger protein 428
chr7_+_24507006 11.862 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr13_-_22042949 11.720 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr13_+_23751069 10.191 ENSMUST00000078369.1
Hist1h2ab
histone cluster 1, H2ab
chr7_+_24507057 10.146 ENSMUST00000071361.6
Zfp428
zinc finger protein 428
chr11_+_58954675 10.005 ENSMUST00000047697.5
ENSMUST00000108817.3
Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr13_-_21833575 9.949 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr13_-_22035589 9.476 ENSMUST00000091742.4
Hist1h2ah
histone cluster 1, H2ah
chr13_-_23571151 9.277 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chr3_-_96240317 9.102 ENSMUST00000078756.5
Hist2h2aa2
histone cluster 2, H2aa2
chr7_+_24507122 8.938 ENSMUST00000177205.1
Zfp428
zinc finger protein 428
chr13_+_23574381 8.877 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr11_+_58948890 8.654 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr3_+_96245530 8.553 ENSMUST00000074976.6
Hist2h2aa1
histone cluster 2, H2aa1
chr7_+_126776939 7.086 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr13_-_23683941 6.878 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr4_+_97777606 6.841 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr13_+_23684192 5.741 ENSMUST00000018246.4
Hist1h2bc
histone cluster 1, H2bc
chr3_-_96220880 5.643 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr2_-_30474199 5.582 ENSMUST00000065134.2
Ier5l
immediate early response 5-like

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 108.9 GO:0006342 chromatin silencing(GO:0006342)
0.2 17.1 GO:0006334 nucleosome assembly(GO:0006334)
1.2 13.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 10.8 GO:0060074 synapse maturation(GO:0060074)
2.9 8.8 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 7.8 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
1.4 7.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.8 5.7 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.2 5.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 4.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 4.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.8 4.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 3.6 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.2 3.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 3.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 2.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 2.7 GO:0001541 ovarian follicle development(GO:0001541)
0.5 2.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 2.5 GO:0007612 learning(GO:0007612)
0.8 2.4 GO:0070269 pyroptosis(GO:0070269)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 73.0 GO:0000790 nuclear chromatin(GO:0000790)
1.2 41.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.6 25.6 GO:0000786 nucleosome(GO:0000786)
0.6 6.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 5.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 5.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 5.2 GO:0005776 autophagosome(GO:0005776)
0.1 4.5 GO:0042734 presynaptic membrane(GO:0042734)
0.1 3.5 GO:0044295 axonal growth cone(GO:0044295)
0.4 3.0 GO:0035102 PRC1 complex(GO:0035102)
0.2 2.5 GO:0042788 polysomal ribosome(GO:0042788)
0.6 2.4 GO:0061702 inflammasome complex(GO:0061702)
0.6 2.4 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.4 2.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 2.1 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.8 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.8 GO:0043195 terminal bouton(GO:0043195)
0.0 1.0 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 47.2 GO:0046872 metal ion binding(GO:0046872)
0.0 45.7 GO:0003677 DNA binding(GO:0003677)
0.1 29.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 10.8 GO:0030674 protein binding, bridging(GO:0030674)
2.9 8.8 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 7.7 GO:0005496 steroid binding(GO:0005496)
0.1 5.9 GO:0043130 ubiquitin binding(GO:0043130)
0.4 5.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.9 5.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 4.5 GO:0005262 calcium channel activity(GO:0005262)
0.1 3.8 GO:0070888 E-box binding(GO:0070888)
0.7 3.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 3.1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 2.9 GO:0042393 histone binding(GO:0042393)
0.1 2.7 GO:0003785 actin monomer binding(GO:0003785)
0.2 2.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.4 GO:0017091 AU-rich element binding(GO:0017091)
0.4 2.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 2.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.5 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)