Motif ID: Pou3f2

Z-value: 0.711


Transcription factors associated with Pou3f2:

Gene SymbolEntrez IDGene Name
Pou3f2 ENSMUSG00000095139.1 Pou3f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f2mm10_v2_chr4_-_22488296_224883660.755.4e-07Click!


Activity profile for motif Pou3f2.

activity profile for motif Pou3f2


Sorted Z-values histogram for motif Pou3f2

Sorted Z-values for motif Pou3f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_103843685 4.419 ENSMUST00000172237.1
 Ednrb
endothelin receptor type B
chr6_+_90465287 4.109 ENSMUST00000113530.1
 Klf15
Kruppel-like factor 15
chr14_-_103844173 4.096 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr16_-_36784924 3.643 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
 Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr18_+_5593566 3.448 ENSMUST00000160910.1
 Zeb1
zinc finger E-box binding homeobox 1
chr10_+_57794335 3.361 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr16_-_36784784 3.130 ENSMUST00000165531.1
 Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr4_-_109665249 2.743 ENSMUST00000063531.4
 Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr12_+_52699297 2.275 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6
chr14_-_88471396 2.154 ENSMUST00000061628.5
 Pcdh20
protocadherin 20
chr4_-_110286581 2.152 ENSMUST00000138972.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_+_88965812 1.952 ENSMUST00000090933.4
 Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_-_150392719 1.924 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr5_+_14025305 1.908 ENSMUST00000073957.6
 Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr14_+_84443553 1.756 ENSMUST00000071370.5
 Pcdh17
protocadherin 17
chr13_-_110280103 1.706 ENSMUST00000167824.1
 Rab3c
RAB3C, member RAS oncogene family
chr7_+_51621830 1.637 ENSMUST00000032710.5
 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chrX_-_95166307 1.600 ENSMUST00000113873.2
ENSMUST00000113876.2
ENSMUST00000113885.1
ENSMUST00000113883.1
ENSMUST00000182001.1
ENSMUST00000113882.1
ENSMUST00000113878.1
ENSMUST00000182562.1
 Arhgef9







CDC42 guanine nucleotide exchange factor (GEF) 9







chr11_+_23256566 1.578 ENSMUST00000136235.1
 Xpo1
exportin 1, CRM1 homolog (yeast)
chr3_+_27984145 1.560 ENSMUST00000067757.4
 Pld1
phospholipase D1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 8.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
1.7 6.8 GO:0042938 dipeptide transport(GO:0042938)
0.3 4.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.5 3.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 3.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 2.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.6 2.3 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 2.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.3 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 2.0 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 1.9 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.2 1.8 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 1.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.6 1.7 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.0 1.7 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 1.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.6 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 1.6 GO:0043113 receptor clustering(GO:0043113)
0.5 1.5 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.8 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 2.2 GO:0042788 polysomal ribosome(GO:0042788)
0.2 2.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.0 1.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.6 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.2 0.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.6 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.5 GO:0042581 specific granule(GO:0042581)
0.1 0.4 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 8.5 GO:0004962 endothelin receptor activity(GO:0004962)
1.4 6.8 GO:0042895 antibiotic transporter activity(GO:0042895)
0.4 3.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 3.4 GO:0070888 E-box binding(GO:0070888)
0.2 2.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 2.3 GO:0043495 protein anchor(GO:0043495)
0.1 2.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.3 2.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.6 1.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.2 1.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.6 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 1.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 1.1 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.2 0.7 GO:0043532 angiostatin binding(GO:0043532)