Motif ID: Pou4f1_Pou6f1

Z-value: 0.839

Transcription factors associated with Pou4f1_Pou6f1:

Gene SymbolEntrez IDGene Name
Pou4f1 ENSMUSG00000048349.8 Pou4f1
Pou6f1 ENSMUSG00000009739.10 Pou6f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f1mm10_v2_chr15_-_100599983_1006000390.645.7e-05Click!
Pou4f1mm10_v2_chr14_-_104467984_104468041-0.441.1e-02Click!


Activity profile for motif Pou4f1_Pou6f1.

activity profile for motif Pou4f1_Pou6f1


Sorted Z-values histogram for motif Pou4f1_Pou6f1

Sorted Z-values for motif Pou4f1_Pou6f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f1_Pou6f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_92161343 5.239 ENSMUST00000068378.5
 Cntn1
contactin 1
chr15_-_100599983 2.902 ENSMUST00000073837.6
 Pou6f1
POU domain, class 6, transcription factor 1
chr15_-_100599864 2.567 ENSMUST00000177247.2
ENSMUST00000177505.2
 Pou6f1

POU domain, class 6, transcription factor 1

chr14_-_30353468 2.542 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr13_+_42681513 2.364 ENSMUST00000149235.1
 Phactr1
phosphatase and actin regulator 1
chr16_+_91269759 2.358 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr4_+_152338619 2.270 ENSMUST00000030775.5
ENSMUST00000164662.1
 Chd5

chromodomain helicase DNA binding protein 5

chr9_+_113812547 2.144 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
 Clasp2


CLIP associating protein 2


chr11_+_98348404 2.034 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr18_+_37504264 1.972 ENSMUST00000052179.6
 Pcdhb20
protocadherin beta 20
chr9_-_58202281 1.948 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_+_180101144 1.871 ENSMUST00000133890.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr5_-_70842617 1.868 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr18_+_69593361 1.850 ENSMUST00000114978.2
ENSMUST00000114977.1
 Tcf4

transcription factor 4

chr1_-_176807124 1.847 ENSMUST00000057037.7
 Cep170
centrosomal protein 170
chr13_+_104287855 1.830 ENSMUST00000065766.6
 Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr3_-_152982240 1.805 ENSMUST00000044278.5
 St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr10_-_64090241 1.764 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr9_-_58201705 1.719 ENSMUST00000163200.1
ENSMUST00000165276.1
 Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr4_+_102254993 1.702 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.6 4.9 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 4.5 GO:0007097 nuclear migration(GO:0007097)
0.3 4.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 3.7 GO:0045773 positive regulation of axon extension(GO:0045773)
1.1 3.3 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.2 3.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 2.8 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2 2.6 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.8 2.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 2.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 2.4 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.5 2.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 2.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.7 2.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 1.9 GO:0042118 endothelial cell activation(GO:0042118)
0.0 1.8 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 1.5 GO:0009414 response to water deprivation(GO:0009414)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 6.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.2 4.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 4.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 2.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.3 GO:0055037 recycling endosome(GO:0055037)
0.0 2.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.7 2.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 2.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.0 GO:0042641 actomyosin(GO:0042641)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 1.8 GO:0005769 early endosome(GO:0005769)
0.1 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.4 1.2 GO:0035061 interchromatin granule(GO:0035061)
0.4 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.2 GO:0001948 glycoprotein binding(GO:0001948)
0.4 4.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 3.4 GO:0030552 cAMP binding(GO:0030552)
0.4 3.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 2.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 2.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 2.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 2.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.5 GO:0000287 magnesium ion binding(GO:0000287)
0.1 2.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 2.3 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.7 2.0 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.5 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.8 GO:0017091 AU-rich element binding(GO:0017091)
0.3 1.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.5 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 1.5 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)