Motif ID: Pou4f3

Z-value: 0.463


Transcription factors associated with Pou4f3:

Gene SymbolEntrez IDGene Name
Pou4f3 ENSMUSG00000024497.3 Pou4f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f3mm10_v2_chr18_+_42394539_42394575-0.281.1e-01Click!


Activity profile for motif Pou4f3.

activity profile for motif Pou4f3


Sorted Z-values histogram for motif Pou4f3

Sorted Z-values for motif Pou4f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_194619815 1.333 ENSMUST00000027952.5
Plxna2
plexin A2
chr10_+_37139558 1.157 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr4_-_58499398 0.989 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr1_-_126830632 0.981 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr2_-_140671400 0.864 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr17_-_48432723 0.695 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr10_+_102158858 0.590 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr14_+_58893465 0.476 ENSMUST00000079960.1
Rpl13-ps3
ribosomal protein L13, pseudogene 3
chr9_+_123366921 0.464 ENSMUST00000038863.7
Lars2
leucyl-tRNA synthetase, mitochondrial
chr8_+_83666827 0.442 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr5_+_92809372 0.403 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr13_+_60601921 0.380 ENSMUST00000077453.5
Dapk1
death associated protein kinase 1
chr10_-_76110956 0.377 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr10_-_29144194 0.375 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr1_-_126830786 0.370 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr15_+_79690869 0.357 ENSMUST00000046463.8
Gtpbp1
GTP binding protein 1
chr11_+_114675431 0.348 ENSMUST00000045779.5
Ttyh2
tweety homolog 2 (Drosophila)
chr5_-_120612558 0.345 ENSMUST00000140554.1
ENSMUST00000031599.2
ENSMUST00000177800.1
1110008J03Rik


RIKEN cDNA 1110008J03 gene


chr17_+_21691860 0.319 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr2_-_160619971 0.315 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr7_+_35802593 0.293 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr13_-_58354862 0.292 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr5_-_118244861 0.268 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr1_+_109983737 0.264 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr7_-_138909492 0.250 ENSMUST00000106112.1
Bnip3
BCL2/adenovirus E1B interacting protein 3
chr3_-_33082004 0.219 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chrX_+_9885622 0.218 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr5_-_117287583 0.217 ENSMUST00000111973.1
ENSMUST00000036951.6
Pebp1

phosphatidylethanolamine binding protein 1

chr18_+_56562443 0.217 ENSMUST00000130163.1
ENSMUST00000132628.1
Phax

phosphorylated adaptor for RNA export

chr5_-_3647806 0.216 ENSMUST00000119783.1
ENSMUST00000007559.8
Gatad1

GATA zinc finger domain containing 1

chr5_+_13398688 0.208 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_82496537 0.190 ENSMUST00000179295.1
Gm5435
predicted gene 5435
chr4_+_63558748 0.182 ENSMUST00000077709.4
6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr10_-_37138863 0.172 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr3_+_32436151 0.172 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr8_-_83458386 0.167 ENSMUST00000081506.3
Scoc
short coiled-coil protein
chr9_+_110052016 0.166 ENSMUST00000164930.1
ENSMUST00000163979.1
Map4

microtubule-associated protein 4

chr16_+_11406618 0.151 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr17_+_34647128 0.138 ENSMUST00000015605.8
ENSMUST00000182587.1
Atf6b

activating transcription factor 6 beta

chr11_+_117809687 0.124 ENSMUST00000120928.1
ENSMUST00000175737.1
Syngr2

synaptogyrin 2

chr7_-_38019505 0.119 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr17_+_34647187 0.115 ENSMUST00000173984.1
Atf6b
activating transcription factor 6 beta
chr7_-_101837776 0.113 ENSMUST00000165052.1
Inppl1
inositol polyphosphate phosphatase-like 1
chr9_+_110132015 0.100 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr11_+_117809653 0.098 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr1_+_45795485 0.080 ENSMUST00000147308.1
Wdr75
WD repeat domain 75
chr7_-_46672537 0.078 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr10_+_29143996 0.078 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr18_+_23753708 0.065 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr2_+_132847719 0.060 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr2_+_36230426 0.048 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr17_-_33033367 0.046 ENSMUST00000087654.4
Zfp763
zinc finger protein 763
chr1_-_89933290 0.042 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr14_+_69347587 0.032 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr6_-_24528013 0.027 ENSMUST00000023851.5
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr2_-_73580288 0.025 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr18_+_55057557 0.016 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr10_-_63927434 0.010 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr12_+_72536342 0.008 ENSMUST00000044352.6
Pcnxl4
pecanex-like 4 (Drosophila)
chr2_+_4300462 0.001 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.2 1.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) response to cobalt ion(GO:0032025)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 0.4 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.7 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.2 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 0.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.0 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 1.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.7 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.0 0.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)