Motif ID: Pou5f1

Z-value: 2.179


Transcription factors associated with Pou5f1:

Gene SymbolEntrez IDGene Name
Pou5f1 ENSMUSG00000024406.10 Pou5f1



Activity profile for motif Pou5f1.

activity profile for motif Pou5f1


Sorted Z-values histogram for motif Pou5f1

Sorted Z-values for motif Pou5f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou5f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 42.480 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr6_-_55681257 24.952 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr4_+_97772734 23.276 ENSMUST00000152023.1
 Nfia
nuclear factor I/A
chr3_-_80802789 23.006 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr8_+_54954728 22.976 ENSMUST00000033915.7
 Gpm6a
glycoprotein m6a
chr4_-_64046925 20.905 ENSMUST00000107377.3
 Tnc
tenascin C
chr7_+_24507099 19.178 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr11_-_69605829 18.104 ENSMUST00000047889.6
 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_+_124610573 16.131 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr18_-_42899470 16.114 ENSMUST00000120632.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_-_42899294 15.994 ENSMUST00000117687.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr12_+_29528382 15.018 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr11_+_98741805 13.302 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr12_+_89812467 12.859 ENSMUST00000110133.2
ENSMUST00000110130.2
 Nrxn3

neurexin III

chr18_+_69344503 12.636 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr3_+_76075583 12.568 ENSMUST00000160261.1
 Fstl5
follistatin-like 5
chr8_-_33747724 12.451 ENSMUST00000179364.1
 Smim18
small integral membrane protein 18
chr17_-_91092715 12.354 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chrX_+_166344692 12.318 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr17_-_90455872 12.222 ENSMUST00000174337.1
ENSMUST00000172466.1
 Nrxn1

neurexin I


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 123 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 77.8 GO:0006342 chromatin silencing(GO:0006342)
1.4 47.1 GO:0060074 synapse maturation(GO:0060074)
3.2 44.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
4.3 42.5 GO:0042118 endothelial cell activation(GO:0042118)
4.6 32.1 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.4 28.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 28.1 GO:0031032 actomyosin structure organization(GO:0031032)
1.3 27.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.7 26.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
4.9 24.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.6 23.3 GO:0021542 dentate gyrus development(GO:0021542)
7.7 23.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.7 22.4 GO:0007616 long-term memory(GO:0007616)
5.2 20.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.6 18.7 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
4.5 18.1 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
1.1 14.9 GO:0045161 neuronal ion channel clustering(GO:0045161)
1.2 14.4 GO:0002227 innate immune response in mucosa(GO:0002227)
1.8 12.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.0 11.9 GO:0070914 UV-damage excision repair(GO:0070914)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 71.4 GO:0000790 nuclear chromatin(GO:0000790)
0.6 41.7 GO:0042734 presynaptic membrane(GO:0042734)
1.7 32.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.5 25.6 GO:0044295 axonal growth cone(GO:0044295)
0.7 23.7 GO:0000788 nuclear nucleosome(GO:0000788)
1.4 23.6 GO:0032279 asymmetric synapse(GO:0032279)
0.6 23.4 GO:0000786 nucleosome(GO:0000786)
0.1 23.0 GO:0015629 actin cytoskeleton(GO:0015629)
1.3 20.9 GO:0005614 interstitial matrix(GO:0005614)
3.4 20.4 GO:0044308 axonal spine(GO:0044308)
2.6 18.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 16.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.7 14.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 11.5 GO:0045171 intercellular bridge(GO:0045171)
0.9 11.3 GO:0097449 astrocyte projection(GO:0097449)
0.8 10.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 10.0 GO:0005776 autophagosome(GO:0005776)
0.2 9.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 9.4 GO:0030315 T-tubule(GO:0030315)
0.9 9.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.2 43.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
10.6 42.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.3 32.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.4 31.8 GO:0005262 calcium channel activity(GO:0005262)
2.0 24.6 GO:0097109 neuroligin family protein binding(GO:0097109)
7.7 23.1 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
3.5 20.9 GO:0045545 syndecan binding(GO:0045545)
0.6 20.3 GO:0030215 semaphorin receptor binding(GO:0030215)
1.8 18.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
1.1 14.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 14.8 GO:0003779 actin binding(GO:0003779)
0.3 12.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 11.9 GO:0030674 protein binding, bridging(GO:0030674)
3.8 11.3 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.3 11.3 GO:0017022 myosin binding(GO:0017022)
0.2 10.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 10.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.4 9.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
3.2 9.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 9.5 GO:0005496 steroid binding(GO:0005496)